WGU D115 Advanced Pathophysiology Exam Study Guide with complete solutions | Latest 2025/2026 Update.

WGU D115 Advanced Pathophysiology i,- i,- i,- i,-




Exam Study Guide with complete i,- i,- i,- i,- i,-




solutions | Latest 2025/2026 Update. i,- i,- i,- i,-




What causes Marfan's syndrome?
i,- Defects or deletions
i,- i,- i,-i,- i,- i,- i,- i,-



(pathogenic variants) of the fibrillin-1 (FBN1) gene have been
i,- i,- i,- i,- i,- i,- i,- i,- i,-



shown to cause Marfans syndrome
i,- i,- i,- i,-




at least 25% of Marfan syndrome cases result from a new
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



mutation in the FBN1 gene i,- i,- i,- i,-




spina bifida i,-a congenital defect that occurs during early
i,-i,- i,- i,- i,- i,- i,- i,- i,- i,-



pregnancy when the spinal canal fails to close completely around
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



the spinal cord to protect it
i,- i,- i,- i,- i,-




What can cause Spina Bifida
i,- i,- i,- i,- i,-i,- i,- Decreased folic acid or maternal i,- i,- i,- i,- i,-



use of valproic acid
i,- i,- i,-




Turner syndrome characteristics
i,- i,- i,-i,- i,- Underdeveloped ovaries i,- i,-



(sterile)
Short stature (~ 4'7")
i,- i,- i,-




Webbing of the neck i,- i,- i,-

,Edema
Underdeveloped breasts; wide nipples i,- i,- i,- i,-




High number of aborted fetuses
i,- i,- i,- i,-




Diagnostic testing for Turner's syndrome genetic testing ,
i,- i,- i,- i,- i,-i,- i,- i,- i,- i,-



echo, bone density, and bone age testing are necessary.
i,- i,- i,- i,- i,- i,- i,- i,-




Treatment of Turners syndrome Treatment involves estrogen
i,- i,- i,- i,-i,- i,- i,- i,- i,-



therapy and growth hormone administration. Treat
i,- i,- i,- i,- i,- i,-



symptomatically for all other effects of the dz. i,- i,- i,- i,- i,- i,- i,-




Cushing's Syndrome a condition caused by prolonged
i,- i,-i,- i,- i,- i,- i,- i,- i,-



exposure to high levels of cortisol i,- i,- i,- i,- i,-




Cushing syndrome symptoms i,- fatty hump between shoulders, i,- i,-i,- i,- i,- i,- i,- i,-



a rounded face(moon faced), and pink or purple stretch marks on
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



skin, thinning fragile skin, slow healing of cuts, insect bites and
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



infections, acne, decreased libido, decreased fertility, irregular or
i,- i,- i,- i,- i,- i,- i,- i,-



absent menstrual periods, fatigue, muscle weakness, cognitive
i,- i,- i,- i,- i,- i,- i,-



difficulties, and headaches. i,- i,-




Turner Syndrome A chromosomal disorder in females in
i,- i,-i,- i,- i,- i,- i,- i,- i,- i,-



which either an X chromosome is missing, making the person XO
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



instead of XX, or part of one X chromosome is deleted.
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-

,Tay-Sachs disease A human genetic disease caused by a
i,- i,-i,- i,- i,- i,- i,- i,- i,- i,- i,-



recessive allele that leads to the accumulation of certain lipids in
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



the brain. Seizures, blindness, and degeneration of motor and
i,- i,- i,- i,- i,- i,- i,- i,- i,-



mental performance usually become manifest a few months after
i,- i,- i,- i,- i,- i,- i,- i,- i,-



birth.


Down Syndrome i,- a condition of mild to severe intellectual i,-i,- i,- i,- i,- i,- i,- i,- i,- i,-



disability and associated physical disorders caused by an extra
i,- i,- i,- i,- i,- i,- i,- i,- i,-



copy of chromosome 21
i,- i,- i,-




Marfan Syndrome i,- i,-i,- i,- autosomal dominant trait.. i,- i,- i,-




a genetic disorder that changes the proteins that help make
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



healthy connective tissue. This leads to problems with the
i,- i,- i,- i,- i,- i,- i,- i,- i,-



development of connective tissue, which supports the bones, i,- i,- i,- i,- i,- i,- i,- i,-



muscles, organs, and tissues in your body.
i,- i,- i,- i,- i,- i,-




Marfans syndrome genetic trait type
i,- Autosomal dominant. i,- i,- i,- i,-i,- i,- i,- i,-



inherited in an autosomal pattern which means one copy of the
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



altered gene in each cell is sufficient to cause the disorder.
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-

, Viral hemorragic fevers
i,- spread by contact with infected i,- i,-i,- i,- i,- i,- i,- i,- i,-



animals or insects. Most common hosts are mosquitos, ticks,
i,- i,- i,- i,- i,- i,- i,- i,- i,-



rodents, or bats. i,- i,-




MRSA (methicillin-resistant Staphylococcus aureus)
i,- an i,- i,- i,-i,- i,- i,-



infection caused by specific bacteria that has become resistant to
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



many antibiotics i,-




B12 anemia
i,- cobalamin deficiency, is a condition that i,-i,- i,- i,- i,- i,- i,- i,- i,-



develops when your body can't make enough healthy red blood
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



cells because it doesn't have enough vitamin B12. Your body
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



needs vitamin B12 to make healthy red blood cells, white blood
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



cells, and platelets. (pernicious anemia)
i,- i,- i,- i,-




Pernicious Anemia a type of vitamin B12 anemia. An
i,- i,-i,- i,- i,- i,- i,- i,- i,- i,- i,-



autoimmune condition in which the body's immune system i,- i,- i,- i,- i,- i,- i,- i,-



attacks the actual intrinsic factor (IF) protein or the cells in the
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



lining of your stomach that make it.
i,- i,- i,- i,- i,- i,-




Folate (folic acid) deficiency anemia
i,- - Folate is an essential i,- i,- i,- i,-i,- i,- i,- i,- i,- i,- i,-



vitamin for RNA and DNA synthesis within maturing RBC
i,- i,- i,- i,- i,- i,- i,- i,-




- Absorption of folate occurs in the upper small intestine
i,- i,- i,- i,- i,- i,- i,- i,- i,-