TEST BANK for Psychopharmacology Drugs the Brain and Behavior 24th Edition by Meyer Nursing, All Chapters 1-20

Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing T
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,Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing T
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Chapter 1: Principles of Pharmacology
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MultiplegChoice

1. g
refer(s)gtogspecificgmoleculargchangesgthatgoccurgwhengagdruggbindsgtogagparticulargtarg
etgsitegorgreceptor,gwhile
aregthegresultinggwidespreadgalterationsgingfunction.
a. Druggaction;gtherapeuticgeffects
b. Sidegeffects;gdruggeffects
c. Therapeuticgeffects;gsidegeffects
d. Druggaction;gdruggeffects
Answer:gd
TextbookgReference:gPharmacology:gThegSciencegofgDruggAction

2. Aftergdruggadministrationghasgoccurred,gthegamountgofgdruggingthegbloodgthatgisgfreegtogb
indgatgspecificgtargetgsitesgisgreferredgtogas
a. thegtherapeuticgdose.
b. first-passgeffects.
c. bioavailability.
d. ED50.
Answer:gc
TextbookgReference:gPharmacokineticgFactorsgDetermininggDruggAction

3. Thegspecificgmoleculargchangesgthatgoccurgwhengagdruggbindsgtogagparticulargtargetgsitego
rgreceptorgaregreferredgtogas
a. druggeffects.
b. druggaction.
c. sidegeffects.
d. placebogeffects.
Answer:gb
TextbookgReference:gPharmacology:gThegSciencegofgDruggAction

4. Whichgofgthegfollowinggisgnotgagpossiblegexplanationgforgplacebogeffects?
a. Pavloviangconditioning
b. Geneticgvariation
c. Druggcompetition
d. Expectationgofgoutcome
Answer:gc
TextbookgReference:gPharmacology:gThegSciencegofgDruggAction

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,Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing T
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5. The administrationgofgoxytocinghasgbeengproposedgasgagtreatmentgforgautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:gc
TextbookgReference:gPharmacokineticgFactorsgDetermininggDruggAction

6. Whichgfactorgdoesgnotgaffectgthegpharmacokineticsgofgagdrug?
a. Routegofgadministration
b. Lipidgsolubility
c. Depotgbinding
d. Druggaction
Answer:gd
TextbookgReference:gPharmacokineticgFactorsgDetermininggDruggAction

7. First-passgmetabolismgoccursgwhengdrugsgaregtaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:ga
TextbookgReference:gPharmacokineticgFactorsgDetermininggDruggAction

8. Thegareagpostremagisgonegareagingthegbraingwheregthe isgnotgcomplete.
a. cerebrospinalgfluid
b. blood–braingbarrier
c. choroidgplexus
d. phospholipidgmembrane
Answer:gb
TextbookgReference:gPharmacokineticgFactorsgDetermininggDruggAction

9. First-passgmetabolismgoccursgwithgorallygadministeredgdrugsgbecause
a. theirgabsorptiongisgslowedgbygfood.
b. drugsgabsorbedgintogthegbloodstreamgfromgthegstomachggogtogtheglivergongthegwaygtogg
eneralgcirculation.
c. drugsgmustgfirstgsurvivegthegacidicgenvironmentgofgthegstomach.
d. salivarygenzymesgingthegmouthgbegingthegprocessgofgmetabolism.
Answer:gb
TextbookgReference:gPharmacokineticgFactorsgDetermininggDruggAction

10. Toxicgsubstancesgingthegbloodgtriggergagvomitinggresponsegbygactivatinggthe
a. blood–braingbarrier.
b. choroidgplexus.
c. areagpostrema.
d. mediangeminence.



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, Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing T
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Answer:gc
TextbookgReference:gPharmacokineticgFactorsgDetermininggDruggAction

11. Drugsgadministeredg_ havegthegmostgrapidgonsetgofgaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:gd
TextbookgReference:gPharmacokineticgFactorsgDetermininggDruggAction

12. Ionizationgofgagdruggdependsgongthe ofgthegsolutiongandgthe
ofgthegdrug.
a. pH;gpKa
b. pKa;gpH
c. concentration;glipidgsolubility
d. pH;gconcentration
Answer:ga
TextbookgReference:gPharmacokineticgFactorsgDetermininggDruggAction

13. Thegabsorptiongofgagdruggdependsgongallgofgthegfollowinggexcept
a. lipidgsolubility.
b. ionization.
c. bodygtemperature.
d. thegconcentrationgofgthegdrug.
Answer:gc
TextbookgReference:gPharmacokineticgFactorsgDetermininggDruggAction

14. Drugsgthatgare shouldgbegavoidedgbygwomengofgchildbearinggage.
a. teratogenic
b. ablegtogcrossgthegplacentalgbarrier
c. psychoactive
d. highlyglipid-soluble
Answer:ga
TextbookgReference:gPharmacokineticgFactorsgDetermininggDruggAction

15. Agentsgthatginducegdevelopmentalgabnormalitiesgingagfetusgaregknowngas
a. psychoactivegdrugs.
b. illicitgdrugs.
c. teratogens.
d. placentalgdrugs.
Answer:gc
TextbookgReference:gPharmacokineticgFactorsgDetermininggDruggAction

16. Depotgbindinggisgsaidgtogoccurgwhengdrugs
a. bindgtogtheirgtargetgsites.



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