FUNDAMENTAL QUESTION BANK LATEST
2025/2026 EXAM COMPLETE QUESTIONS AND
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Terms in this set (244)
During what trimester is a 1st trimester (fetus most at risk d/t rapid growth)
pregnant woman most at
risk for adverse drug
reactions with potential
long term consequences?
Recommendations of medications inappropriate for
What is BEERS criteria?
elderly (65 and older), prescriber ultimately decides
liver enzyme system where medications are
What is the CYP450
metabolized, can either be inducers or inhibitors and
(cytochrome P450)
create drug-drug interactions
Speed up metabolism of drugs (drug is cleared
CYP450 inducers faster), drug has lesser effect (decrease blood levels
of drug), elevate CYP450 enzymes
CYP450 inducers "Bullshit Crap GPS INDUCES rage"
pneumonic
Barbituates, St John wort, Carbamazepine, rifampin,
CYP450 inducer drug
alcohol, phenytoin, griseofulvin, phenobarbital,
names
sulfonylureas
, inhibit metabolism, increase blood levels of
CYP450 inhibitors
medications
"VISA credit card debt INHIBITS spending on
CYP450 pneumonic
designers like CK to look GQ"
Valproate, isoniazid, sulfonamides, amiodarone,
CYP450 inhibitors drug
chloramphenicol, ketoconazole, grapefruit juice,
names
quinidine
Physiological changes increase glomerular filtration rate leads to increase
during pregnancy that durg excretion
impact increase hepatic metabolism
pharmacodynamics and decrease tone and motility of bowel
pharmacokinetic increase drug absorption
properties of drugs?
Antiepileptic drugs, antimicrobials such as
Examples of medications tetracyclines and fluoroquinolones, vitamin A in large
that can be teratogenic doses, some anticoagulants, and hormonal
medications such as diethylstilbestrol (DES).
How is absorption of slow and erratic due to low blood flow in muscles first
intramuscular medications few days of life
different in neonates?
Why is absorption of delayed gastric emptying
medication in the stomach
increased in infancy?
glucocorticoids, discoloration of developing teeth
Some medications that
with tetracyclines, and kernicterus with sulfonamides,
should be avoided in the
levofloxacin (antibiotics)
pediatric patient?
aspirin (Severe intoxication from acute overdose)
, dosage size and timing
route and technique of administration
what should be included
duration of treatment
in medication
drug storage
administration patient
nature and time course of desired responses
education?
nature and time course of adverse responses
finish taking antibiotic
reduced renal function
polypharmacy (the use of five or more medications
daily)
greater severity of illness
What are some things that
presence of comorbidities
put the elderly patient at
use of drugs that have a low therapeutic index (e.g.,
higher risk for adverse
digoxin)
drug reactions?
increased individual variation secondary to altered
pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence
obtaining a thorough drug history that includes over-
the-counter medications
considering pharmacokinetic and pharmacodynamics
changes due to age
monitoring the patient's clinical response and plasma
How can healthcare drug levels
providers decrease using the simplest regimen possible
likelihood of an elderly monitoring for drug-drug interactions and iatrogenic
patient experiencing an illness
adverse drug reaction? periodically reviewing the need for continued drug
therapy
encouraging the patient to dispose of old
medications
taking steps to promote adherence and to avoid
drugs on the Beers list
, simplifying drug regimens
providing clear and concise verbal and written
instructions
using an appropriate dosage form
How can we promote
clearly labeling and dispensing easy-to-open
medication adherence
containers
with elderly patients?
developing daily reminders
monitoring frequently
affordability of drugs
support systems
Why do nitrates need to Need nitrate free interval so tolerance doesn't
be taken no later than 4 develop
PM?
Gender and race
Genetics and pharmacogenomics
Variability in absorption
Nine factors that impact placebo effect
outcome of medication? Tolerance
patho
age
bodyweight
Do you need informed yes
consent for genetic
testing?
What is the purpose of the Protects patients from discrimination by employers
Genetic Information Non- and insurance providers based on genetic information
Discriminatory Act?
Practice authority refers to the nurse practitioner's
Difference between ability to practice without physician oversight,
practice authority and whereas prescriptive authority refers to the nurse
prescriptive authority? practitioner's authority to prescribe medications
independently and without limitations.