Murphy Biochem Rutgers Exam 2
Questions and Answers 100% Pass
Place the following reaction intermediates of the CAC in chronological order
i. malate ii. fumarate iii. succinyl CoA iv. citrate v. a-ketoglutarate - ✔✔iv, v, iii, ii, i
Oxalosuccinate is a transient intermediate formed during which of the following
reactions? - ✔✔isocitrate to a-ketoglutarate
FADH2 is a product of which of the following reactions? - ✔✔succinate to fumarate
NADH is produced in which of the following reactions? - ✔✔a-ketoglutarate to succinyl
CoA
Which of the following reactions can be described as anaplerotic? - ✔✔pyruvate + co2
to oxaloacetate
The enzymes that are unique to the glyoxylate cycle include ____________ -
✔✔isocitrate lyase
The regulated enzyme of the CAC include _________ - ✔✔a-ketoglutarate
dehydrogenase
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,The enzymes involved in citrate metabolism include all of the following except
________ - ✔✔malate synthase
Redox potential is best defined as - ✔✔the tendency of a species to gain or lose electrons
In order to determine the standard voltage of a reaction - ✔✔the standard cells must be
written as they occur in the reaction and the voltages are added
Which of the following reactions is an oxidation reaction?
a. NaOH + HCl -> NaCl + H2O
b. CH3COOH -> CH3COO- + H+
c. CH3CHO -> CH3CH2OH
d. CH3CH2OH -> CH3CHO
e. CH2=CH2 + H2O -> CH3CH2OH - ✔✔CH3CH2OH -> CH3CHO
Which of the following reactions has an oxidized product?
a. carboxylic acid -> aldehyde
b. R-SH + R-SH -> R-S-S-R
c. alcohol -> ketone
d. glutamate -> a-ketoglutarate
e. none of the above - ✔✔none of the above
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,In any redox reaction, an electron donor is - ✔✔the reducing agent
In an redox reaction, an electron acceptor is - ✔✔converted to an electron donor with
the gain of one or more electrons
Each turn of the CAC produces how many moles of CO2? - ✔✔2
Acetyl CoA that is consumed by the CAC is produced from which of the following
biochemical pathways?
a. glycolysis
b. fatty acid oxidation
c. purine catabolism
d. urea cycle
e. both A and B are correct - ✔✔both A and B are correct
Which of the following is the strongest reducing agent?
a. FADH2 (+ 0.22 V)
b. H2 (+ 0.424 V)
c. cytochrome a * Fe 2+ (-0.29 V)
d. lactate (+0.19 V)
e. H2O (-0.82 V) - ✔✔H2
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, Which of the following reacts with the acetyl-CoA to form citrate? - ✔✔oxaloacetate
The redox reaction in which succinate is converted to fumarate uses FAD rather than
NAD+ because? - ✔✔FAD is a stronger oxidizing agent than NAD+
Which of the following CAC enzymes are closely regulated?
a. citrate synthase
b. isocitrate dehydrogenase
c. a-ketoglutarate dehydrogenase
d. both A and B are correct
e. A, B, and C are all correct - ✔✔A, B, and C are all correct
Which of the following requires GDP? - ✔✔succinyl-CoA to succinate
How many oxidation steps are there in the CAC? - ✔✔4
Which of the following is a cofactor for the conversion of succinate to fumarate? -
✔✔FAD
Which of the following reactions involves a substrate level phosphorylation? -
✔✔succinyl-CoA to succinate
The carbon skeletons of which of the following can be incorporated directly into the
protein?
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Questions and Answers 100% Pass
Place the following reaction intermediates of the CAC in chronological order
i. malate ii. fumarate iii. succinyl CoA iv. citrate v. a-ketoglutarate - ✔✔iv, v, iii, ii, i
Oxalosuccinate is a transient intermediate formed during which of the following
reactions? - ✔✔isocitrate to a-ketoglutarate
FADH2 is a product of which of the following reactions? - ✔✔succinate to fumarate
NADH is produced in which of the following reactions? - ✔✔a-ketoglutarate to succinyl
CoA
Which of the following reactions can be described as anaplerotic? - ✔✔pyruvate + co2
to oxaloacetate
The enzymes that are unique to the glyoxylate cycle include ____________ -
✔✔isocitrate lyase
The regulated enzyme of the CAC include _________ - ✔✔a-ketoglutarate
dehydrogenase
Katelyn Whitman, All Rights Reserved © 2025 1
,The enzymes involved in citrate metabolism include all of the following except
________ - ✔✔malate synthase
Redox potential is best defined as - ✔✔the tendency of a species to gain or lose electrons
In order to determine the standard voltage of a reaction - ✔✔the standard cells must be
written as they occur in the reaction and the voltages are added
Which of the following reactions is an oxidation reaction?
a. NaOH + HCl -> NaCl + H2O
b. CH3COOH -> CH3COO- + H+
c. CH3CHO -> CH3CH2OH
d. CH3CH2OH -> CH3CHO
e. CH2=CH2 + H2O -> CH3CH2OH - ✔✔CH3CH2OH -> CH3CHO
Which of the following reactions has an oxidized product?
a. carboxylic acid -> aldehyde
b. R-SH + R-SH -> R-S-S-R
c. alcohol -> ketone
d. glutamate -> a-ketoglutarate
e. none of the above - ✔✔none of the above
Katelyn Whitman, All Rights Reserved © 2025 2
,In any redox reaction, an electron donor is - ✔✔the reducing agent
In an redox reaction, an electron acceptor is - ✔✔converted to an electron donor with
the gain of one or more electrons
Each turn of the CAC produces how many moles of CO2? - ✔✔2
Acetyl CoA that is consumed by the CAC is produced from which of the following
biochemical pathways?
a. glycolysis
b. fatty acid oxidation
c. purine catabolism
d. urea cycle
e. both A and B are correct - ✔✔both A and B are correct
Which of the following is the strongest reducing agent?
a. FADH2 (+ 0.22 V)
b. H2 (+ 0.424 V)
c. cytochrome a * Fe 2+ (-0.29 V)
d. lactate (+0.19 V)
e. H2O (-0.82 V) - ✔✔H2
Katelyn Whitman, All Rights Reserved © 2025 3
, Which of the following reacts with the acetyl-CoA to form citrate? - ✔✔oxaloacetate
The redox reaction in which succinate is converted to fumarate uses FAD rather than
NAD+ because? - ✔✔FAD is a stronger oxidizing agent than NAD+
Which of the following CAC enzymes are closely regulated?
a. citrate synthase
b. isocitrate dehydrogenase
c. a-ketoglutarate dehydrogenase
d. both A and B are correct
e. A, B, and C are all correct - ✔✔A, B, and C are all correct
Which of the following requires GDP? - ✔✔succinyl-CoA to succinate
How many oxidation steps are there in the CAC? - ✔✔4
Which of the following is a cofactor for the conversion of succinate to fumarate? -
✔✔FAD
Which of the following reactions involves a substrate level phosphorylation? -
✔✔succinyl-CoA to succinate
The carbon skeletons of which of the following can be incorporated directly into the
protein?
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