A patient is currently taking cyclosporine and has a new order for fluconazole. The
nurse anticipates which of the following?
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Fluconazole may increase cyclosporine blood levels; therefore the dose
may need to be reduced
,when shoulda quality of life assessment in a patient with chronic gvhd occur?
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at least every three months and whenever steroids are tapered
preferred treatment for GVHD
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high dose of steroids
BCNU (carmustine)
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causes DNA cross-links and strands break
inhibits DNA repair and causes carbamylation of cellular proteins to
destroy cells
crosses the blood-brain barrier (because of lipid solubility)
requires pre and post hydration
Which of the following cell types play an important role in the movement of
hematopoietic stem cells from the marrow to the peripheral circulation?
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, Bone marrow stromal cells provide the required microenvironment for the
release of hemopoietic cells to the circulation.
A patient who received an allogeneic HSCT twelve years ago has been diagnosed
with non squamous cell carcinoma. Which of the following does the nurse suspect
increased the risk of developing this secondary malignancy?
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History of radiation-containing conditioning regimen
Cyclosporine mechanism of action
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prevents IL-2 gene expression, therefore impairing IL-2 and activation of T
lymphocytes.
begin cyclosporine 2 days before to ensure therapeutic serum levels when
the graft is infused.
matched sibiling/related
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, human leukocyte antigen(HLA) identical relative
a: no potential stem cell contamination, access to cells because the donor
is related
d: only 25 % of the population has a sibling match, risk of GVHD
Gut GVHD stage 3
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diarrhea >1500 or 90 ml/kg
stem sources that decrease the incidence of GVHD
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umbilical cord blood and bone marrow
How should the healthcare team address the psychosocial needs of transplant
patients and caregivers?
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Members of the team must work together to educate the patient, family,
and caregiver through each step of the transplant.
xerostomia te oat is higher to develop
nurse anticipates which of the following?
Give this one a try later!
Fluconazole may increase cyclosporine blood levels; therefore the dose
may need to be reduced
,when shoulda quality of life assessment in a patient with chronic gvhd occur?
Give this one a try later!
at least every three months and whenever steroids are tapered
preferred treatment for GVHD
Give this one a try later!
high dose of steroids
BCNU (carmustine)
Give this one a try later!
causes DNA cross-links and strands break
inhibits DNA repair and causes carbamylation of cellular proteins to
destroy cells
crosses the blood-brain barrier (because of lipid solubility)
requires pre and post hydration
Which of the following cell types play an important role in the movement of
hematopoietic stem cells from the marrow to the peripheral circulation?
Give this one a try later!
, Bone marrow stromal cells provide the required microenvironment for the
release of hemopoietic cells to the circulation.
A patient who received an allogeneic HSCT twelve years ago has been diagnosed
with non squamous cell carcinoma. Which of the following does the nurse suspect
increased the risk of developing this secondary malignancy?
Give this one a try later!
History of radiation-containing conditioning regimen
Cyclosporine mechanism of action
Give this one a try later!
prevents IL-2 gene expression, therefore impairing IL-2 and activation of T
lymphocytes.
begin cyclosporine 2 days before to ensure therapeutic serum levels when
the graft is infused.
matched sibiling/related
Give this one a try later!
, human leukocyte antigen(HLA) identical relative
a: no potential stem cell contamination, access to cells because the donor
is related
d: only 25 % of the population has a sibling match, risk of GVHD
Gut GVHD stage 3
Give this one a try later!
diarrhea >1500 or 90 ml/kg
stem sources that decrease the incidence of GVHD
Give this one a try later!
umbilical cord blood and bone marrow
How should the healthcare team address the psychosocial needs of transplant
patients and caregivers?
Give this one a try later!
Members of the team must work together to educate the patient, family,
and caregiver through each step of the transplant.
xerostomia te oat is higher to develop
