PH 346 Bacterial Pathogens Test With
Correct Solution
staph aureus - ANSWER - gram positive cocci in clusters, catalase +, coagulase +, gold
colonies on blood agar
- MSSA, MRSA, CA-MRSA, HA-MRSA, VISA, VRSA
- skin, mucous membrane, respiratory tract, air
- Skin and soft tissue infections (impetigo, folliculitis, erysipelas, cellulitis),
toxin-mediated diseases (scalded skin syndrome, toxic shock syndrome)
- resistant to nearly all b lactams via b lactamase/PBP
- cloxacillin works against MSSA only
staph epidermidis - ANSWER - gram positive cocci in clusters, catalase +, coagulase -,
white colonies on blood agar
- skin, mucous, respiratory tract, air
- prosthetic material infections (IV, catheter, sepsis, endocarditis)
- resistant to nearly all b lactams
- cloxacillin works against MSSE only
Staphylococcus saprophyticus - ANSWER - gram positive cocci in clusters, catalase +,
coagulase -, white colonies on blood agar
- genitourinary mucus membranes of childbearing women
- UTI
Streptococcus pyogenes - ANSWER - Group A, gram pos cocci in chains, catalase -,
beta hemolytic, reacts with Anti-A antibodies, PYR +,
- 250 M protein types
- ubiquitous, skin, mucus, throats of asymp carriers
- skin and soft tissue infections (abscesses, erysipelas, cellulitis), Pharyngitis, tonsillitis,
immune-mediated diseases, toxin-mediated (scarlet fever, necrotizing fasciitis, toxic
shock syndrome)
, - susceptible to b lactams a
Streptococcus agalactiae - ANSWER - gram pos cocci in chains, catalase -, Group B
beta hemolytic
- 10 capsular subtypes
- vagina, cervix, GI tract
- Postpartum sepsis
Neonatal pneumonia
Neonatal sepsis
Neonatal meningitis
- susceptible to b lactams
Streptococcus pneumonia - ANSWER - gram pos diplococci, catalase -, alpha hemolytic,
- 100 capsular types (protect from phagocytosis)
- URT, asymp carriers mostly in children
- Pneumonia, Otitis media, Sinusitis, Sepsis, Meningitis
- resistant to b lactams via PBP
viridans group streptococci - ANSWER - gram pos cocci in chains, catalase -, alpha or
gamma hemolytic
- mouth, GI tract, resp tract, unogenital tract, environment
- dental caries, brain, oropharnyx, GI tract abscesses, sepsis, endocarditis
- resistant to b lactams via b lactamase/PBP
Enterococcus faecalis and faecium - ANSWER - gram pos cocci chains, alpha or
gamma-hemolytic, bile esculin +, react with group D antiserum, grow in high salt, 10C
and 40C, high pH, survive 60C for 30 mins,
- group D, VRE
- skin, mouth, GI tract, urogenital tract, environment
- post surgical wound infections, intra abdominal infections and abscesses, sepsis,
endocarditis
- faecalis susceptible to amp/amox
- faecium less susceptible to b lactams via b lactamase, PBP
Correct Solution
staph aureus - ANSWER - gram positive cocci in clusters, catalase +, coagulase +, gold
colonies on blood agar
- MSSA, MRSA, CA-MRSA, HA-MRSA, VISA, VRSA
- skin, mucous membrane, respiratory tract, air
- Skin and soft tissue infections (impetigo, folliculitis, erysipelas, cellulitis),
toxin-mediated diseases (scalded skin syndrome, toxic shock syndrome)
- resistant to nearly all b lactams via b lactamase/PBP
- cloxacillin works against MSSA only
staph epidermidis - ANSWER - gram positive cocci in clusters, catalase +, coagulase -,
white colonies on blood agar
- skin, mucous, respiratory tract, air
- prosthetic material infections (IV, catheter, sepsis, endocarditis)
- resistant to nearly all b lactams
- cloxacillin works against MSSE only
Staphylococcus saprophyticus - ANSWER - gram positive cocci in clusters, catalase +,
coagulase -, white colonies on blood agar
- genitourinary mucus membranes of childbearing women
- UTI
Streptococcus pyogenes - ANSWER - Group A, gram pos cocci in chains, catalase -,
beta hemolytic, reacts with Anti-A antibodies, PYR +,
- 250 M protein types
- ubiquitous, skin, mucus, throats of asymp carriers
- skin and soft tissue infections (abscesses, erysipelas, cellulitis), Pharyngitis, tonsillitis,
immune-mediated diseases, toxin-mediated (scarlet fever, necrotizing fasciitis, toxic
shock syndrome)
, - susceptible to b lactams a
Streptococcus agalactiae - ANSWER - gram pos cocci in chains, catalase -, Group B
beta hemolytic
- 10 capsular subtypes
- vagina, cervix, GI tract
- Postpartum sepsis
Neonatal pneumonia
Neonatal sepsis
Neonatal meningitis
- susceptible to b lactams
Streptococcus pneumonia - ANSWER - gram pos diplococci, catalase -, alpha hemolytic,
- 100 capsular types (protect from phagocytosis)
- URT, asymp carriers mostly in children
- Pneumonia, Otitis media, Sinusitis, Sepsis, Meningitis
- resistant to b lactams via PBP
viridans group streptococci - ANSWER - gram pos cocci in chains, catalase -, alpha or
gamma hemolytic
- mouth, GI tract, resp tract, unogenital tract, environment
- dental caries, brain, oropharnyx, GI tract abscesses, sepsis, endocarditis
- resistant to b lactams via b lactamase/PBP
Enterococcus faecalis and faecium - ANSWER - gram pos cocci chains, alpha or
gamma-hemolytic, bile esculin +, react with group D antiserum, grow in high salt, 10C
and 40C, high pH, survive 60C for 30 mins,
- group D, VRE
- skin, mouth, GI tract, urogenital tract, environment
- post surgical wound infections, intra abdominal infections and abscesses, sepsis,
endocarditis
- faecalis susceptible to amp/amox
- faecium less susceptible to b lactams via b lactamase, PBP
