STUDY Guide For Lehne's Pharmacology For Nursing Care
12th Edition
By Jacqueline Rosenjack Burchum Latest Update.
, Table Of Contents
Chapter 01: Orientation To Pharmacology.......................................................................................................................... 5
Chapter 02: Application Of Pharmacology In Nursing Practice.......................................................................................... 6
Chapter 03: Drug Regulation, Development, Names, And Information............................................................................ 11
Chapter 04: Pharmacokinetics........................................................................................................................................... 14
Chapter 05: Pharmacodynamics........................................................................................................................................ 19
Chapter 06: Drug Interactions ........................................................................................................................................... 21
Chapter 07: Adverse Drug Reactions And Medication Errors .......................................................................................... 26
Chapter 08: Individual Variation To Drug Responses....................................................................................................... 31
Chapter 09: Genetic And Genomic Considerations........................................................................................................... 35
Chapter 10: Introduction To Immunomodulators .............................................................................................................. 38
Chapter 11: Drug Therapy During Pregnancy And Breast-Feeding.................................................................................. 41
Chapter 12: Drug Therapy In Pediatric Patients ................................................................................................................ 44
Chapter 13: Drug Therapy In Older Adults....................................................................................................................... 48
Chapter 14: Basic Principles Of Neuropharmacology....................................................................................................... 53
Chapter 15: Physiology Of The Peripheral Nervous System............................................................................................. 56
Chapter 16: Muscarinic Agonists ...................................................................................................................................... 59
Chapter 17: Muscarinic Antagonists ................................................................................................................................. 62
Chapter 18: Cholinesterase Inhibitors And Their Use In Myasthenia Gravis.................................................................... 65
Chapter 19: Drugs That Block Nicotinic Cholinergic Transmission ................................................................................. 68
Chapter 20: Adrenergic Agonists ...................................................................................................................................... 72
Chapter 21: Adrenergic Antagonists ................................................................................................................................. 76
Chapter 22: Indirect-Acting Antiadrenergic Agents.......................................................................................................... 83
Chapter 23: Introduction To Central Nervous System Pharmacology .............................................................................. 87
Chapter 24: Drugs For Parkinson Disease......................................................................................................................... 90
Chapter 25: Drugs For Alzheimer Disease........................................................................................................................ 95
Chapter 26: Drugs For Multiple Sclerosis ......................................................................................................................... 99
Chapter 27: Drugs For Seizure Disorders ....................................................................................................................... 104
Chapter 28: Drugs For Muscle Spasm And Spasticity .................................................................................................... 111
Chapter 29: Local Anesthetics ........................................................................................................................................ 114
Chapter 30: General Anesthetics..................................................................................................................................... 118
Chapter 31: Opioid Analgesics, Opioid Antagonists, And Nonopioid Centrally Actinganalgesics ................................. 124
Chapter 32: Pain Management In Patients With Cancer ................................................................................................. 129
Chapter 33: Drugs For Headache .................................................................................................................................... 136
Chapter 34: Antipsychotic Agents And Their Use In Schizophrenia .............................................................................. 140
Chapter 35: Antidepressants ........................................................................................................................................... 146
Chapter 36: Drugs For Bipolar Disorder ......................................................................................................................... 152
Chapter 37: Sedative-Hypnotic Drugs............................................................................................................................. 157
Chapter 38: Management Of Anxiety Disorders ............................................................................................................. 162
Chapter 39: Central Nervous System Stimulants And Attention-Deficit/Hyperactivitydisorder ..................................... 166
Chapter 40: Substance Use Disorders I: Basic Considerations........................................................................................ 170
Chapter 41: Substance Use Disorders Ii: Alcohol ........................................................................................................... 174
,Chapter 42: Substance Use Disorders Iii: Nicotine ......................................................................................................... 180
Chapter 43: Substance Use Disorders Iv: Major Drugs Of Abuse Other Than Alcohol Andnicotine ............................. 184
Chapter 44: Diuretics ...................................................................................................................................................... 190
Chapter 45: Agents Affecting The Volume And Ion Content Of Body Fluids................................................................ 194
Chapter 46: Review Of Hemodynamics.......................................................................................................................... 199
Chapter 47: Drugs Acting On The Renin-Angiotensin-Aldosterone System .................................................................. 201
Chapter 48: Calcium Channel Blockers .......................................................................................................................... 206
Chapter 49: Vasodilators................................................................................................................................................. 208
Chapter 50: Drugs For Hypertension .............................................................................................................................. 212
Chapter 51: Drugs For Heart Failure............................................................................................................................... 219
Chapter 52: Antidysrhythmic Drugs ............................................................................................................................... 226
Chapter 53: Drugs That Help Normalize Cholesterol And Triglyceride Levels.............................................................. 233
Chapter 54: Drugs For Angina Pectoris .......................................................................................................................... 239
Chapter 55: Anticoagulant, Antiplatelet, And Thrombolytic Drugs................................................................................ 245
Chapter 56: Management Of St-Elevation Myocardial Infarction................................................................................... 252
Chapter 57: Drugs For Hemophilia ................................................................................................................................. 256
Chapter 58: Drugs For Deficiency Anemias ................................................................................................................... 260
Chapter 59: Hematopoietic Agents ................................................................................................................................. 266
Chapter 60: Drugs For Diabetes Mellitus........................................................................................................................ 270
Chapter 61: Drugs For Thyroid Disorders ...................................................................................................................... 276
Chapter 62: Drugs Related To Hypothalamic And Pituitary Function ............................................................................ 281
Chapter 63: Drugs For Disorders Of The Adrenal Cortex ............................................................................................... 285
Chapter 64: Estrogens And Progestins: Basic Pharmacology And Noncontraceptiveapplications.................................. 289
Chapter 65: Birth Control ............................................................................................................................................... 293
Chapter 66: Drug Therapy For Infertility ........................................................................................................................ 298
Chapter 67: Drugs That Affect Uterine Function ............................................................................................................ 302
Chapter 68: Androgens ................................................................................................................................................... 307
Chapter 69: Drugs For Erectile Dysfunction And Benign Prostatic Hyperplasia ............................................................ 311
Chapter 70: Review Of The Immune System ................................................................................................................. 315
Chapter 71: Childhood Immunization ............................................................................................................................. 319
Chapter 72: Immunosuppressants ................................................................................................................................... 324
Chapter 73: Antihistamines............................................................................................................................................. 328
Chapter 74: Cyclooxygenase Inhibitors, Nonsteroidal Anti-Inflammatory Drugs Andacetaminophen ........................... 333
Chapter 75: Glucocorticoids In Nonendocrine Disorders................................................................................................ 338
Chapter 76: Drug Therapy For Rheumatoid Arthritis ..................................................................................................... 344
Chapter 77: Drug Therapy For Gout ............................................................................................................................... 347
Chapter 78: Drugs Affecting Calcium Levels And Bone Mineralization ........................................................................ 350
Chapter 79: Drugs For Asthma And Chronic Obstructive Pulmonary Disease ............................................................... 356
Chapter 80: Drugs For Allergic Rhinitis, Cough, And Colds .......................................................................................... 363
Chapter 81: Drugs For Peptic Ulcer Disease................................................................................................................... 368
Chapter 82: Laxatives ..................................................................................................................................................... 373
Chapter 83: Other Gastrointestinal Drugs ....................................................................................................................... 378
Chapter 84: Vitamins ...................................................................................................................................................... 385
, Chapter 85: Drugs For Weight Loss................................................................................................................................ 391
Chapter 86: Complementary And Alternative Therapy ................................................................................................... 396
Chapter 87: Basic Principles Of Antimicrobial Therapy ................................................................................................. 399
Chapter 88: Drugs That Weaken The Bacterial Cell Wall I: Penicillins ......................................................................... 404
Chapter 89: Drugs That Weaken The Bacterial Cell Wall Ii: Other Drugs ..................................................................... 409
Chapter 90: Bacteriostatic Inhibitors Of Protein Synthesis: Tetracyclines, Macrolides, Andothers ................................ 413
Chapter 91: Aminoglycosides: Bactericidal Inhibitors Of Protein Synthesis .................................................................. 421
Chapter 92: Sulfonamides And Trimethoprim ................................................................................................................ 427
Chapter 93: Drug Therapy For Urinary Tract Infections ................................................................................................. 431
Chapter 94: Antimycobacterial Agents ........................................................................................................................... 437
Chapter 95: Miscellaneous Antibacterial Drugs .............................................................................................................. 444
Chapter 96: Antifungal Agents ....................................................................................................................................... 448
Chapter 97: Antiviral Agents I: Drugs For Non-Hiv Viral Infections ............................................................................. 455
Chapter 98: Antiviral Agents Ii: Drugs For Hiv Infection And Related Opportunisticinfections .................................... 460
Chapter 99: Drug Therapy For Sexually Transmitted Diseases ...................................................................................... 465
Chapter 100: Antiseptics And Disinfectants.................................................................................................................... 469
Chapter 101: Anthelmintics ............................................................................................................................................ 473
Chapter 102: Antiprotozoal Drugs I: Antimalarial Agents .............................................................................................. 476
Chapter 103: Antiprotozoal Drugs Ii: Miscellaneous Agents .......................................................................................... 481
Chapter 104: Ectoparasiticides ........................................................................................................................................ 483
Chapter 105: Basic Principles Of Cancer Chemotherapy................................................................................................ 487
Chapter 106: Anticancer Drugs I: Cytotoxic Agents ....................................................................................................... 493
Chapter 107: Anticancer Drugs Ii: Noncytotoxic Agents................................................................................................ 498
Chapter 108: Drugs For The Eye .................................................................................................................................... 502
Chapter 109: Drugs For The Skin ................................................................................................................................... 507
Chapter 110: Drugs For The Ear ..................................................................................................................................... 514
Chapter 111: Management Of Poisoning ........................................................................................................................ 519
Chapter 112: Potential Weapons Of Biologic, Radiologic, And Chemical Terrorism ..................................................... 523
12th Edition
By Jacqueline Rosenjack Burchum Latest Update.
, Table Of Contents
Chapter 01: Orientation To Pharmacology.......................................................................................................................... 5
Chapter 02: Application Of Pharmacology In Nursing Practice.......................................................................................... 6
Chapter 03: Drug Regulation, Development, Names, And Information............................................................................ 11
Chapter 04: Pharmacokinetics........................................................................................................................................... 14
Chapter 05: Pharmacodynamics........................................................................................................................................ 19
Chapter 06: Drug Interactions ........................................................................................................................................... 21
Chapter 07: Adverse Drug Reactions And Medication Errors .......................................................................................... 26
Chapter 08: Individual Variation To Drug Responses....................................................................................................... 31
Chapter 09: Genetic And Genomic Considerations........................................................................................................... 35
Chapter 10: Introduction To Immunomodulators .............................................................................................................. 38
Chapter 11: Drug Therapy During Pregnancy And Breast-Feeding.................................................................................. 41
Chapter 12: Drug Therapy In Pediatric Patients ................................................................................................................ 44
Chapter 13: Drug Therapy In Older Adults....................................................................................................................... 48
Chapter 14: Basic Principles Of Neuropharmacology....................................................................................................... 53
Chapter 15: Physiology Of The Peripheral Nervous System............................................................................................. 56
Chapter 16: Muscarinic Agonists ...................................................................................................................................... 59
Chapter 17: Muscarinic Antagonists ................................................................................................................................. 62
Chapter 18: Cholinesterase Inhibitors And Their Use In Myasthenia Gravis.................................................................... 65
Chapter 19: Drugs That Block Nicotinic Cholinergic Transmission ................................................................................. 68
Chapter 20: Adrenergic Agonists ...................................................................................................................................... 72
Chapter 21: Adrenergic Antagonists ................................................................................................................................. 76
Chapter 22: Indirect-Acting Antiadrenergic Agents.......................................................................................................... 83
Chapter 23: Introduction To Central Nervous System Pharmacology .............................................................................. 87
Chapter 24: Drugs For Parkinson Disease......................................................................................................................... 90
Chapter 25: Drugs For Alzheimer Disease........................................................................................................................ 95
Chapter 26: Drugs For Multiple Sclerosis ......................................................................................................................... 99
Chapter 27: Drugs For Seizure Disorders ....................................................................................................................... 104
Chapter 28: Drugs For Muscle Spasm And Spasticity .................................................................................................... 111
Chapter 29: Local Anesthetics ........................................................................................................................................ 114
Chapter 30: General Anesthetics..................................................................................................................................... 118
Chapter 31: Opioid Analgesics, Opioid Antagonists, And Nonopioid Centrally Actinganalgesics ................................. 124
Chapter 32: Pain Management In Patients With Cancer ................................................................................................. 129
Chapter 33: Drugs For Headache .................................................................................................................................... 136
Chapter 34: Antipsychotic Agents And Their Use In Schizophrenia .............................................................................. 140
Chapter 35: Antidepressants ........................................................................................................................................... 146
Chapter 36: Drugs For Bipolar Disorder ......................................................................................................................... 152
Chapter 37: Sedative-Hypnotic Drugs............................................................................................................................. 157
Chapter 38: Management Of Anxiety Disorders ............................................................................................................. 162
Chapter 39: Central Nervous System Stimulants And Attention-Deficit/Hyperactivitydisorder ..................................... 166
Chapter 40: Substance Use Disorders I: Basic Considerations........................................................................................ 170
Chapter 41: Substance Use Disorders Ii: Alcohol ........................................................................................................... 174
,Chapter 42: Substance Use Disorders Iii: Nicotine ......................................................................................................... 180
Chapter 43: Substance Use Disorders Iv: Major Drugs Of Abuse Other Than Alcohol Andnicotine ............................. 184
Chapter 44: Diuretics ...................................................................................................................................................... 190
Chapter 45: Agents Affecting The Volume And Ion Content Of Body Fluids................................................................ 194
Chapter 46: Review Of Hemodynamics.......................................................................................................................... 199
Chapter 47: Drugs Acting On The Renin-Angiotensin-Aldosterone System .................................................................. 201
Chapter 48: Calcium Channel Blockers .......................................................................................................................... 206
Chapter 49: Vasodilators................................................................................................................................................. 208
Chapter 50: Drugs For Hypertension .............................................................................................................................. 212
Chapter 51: Drugs For Heart Failure............................................................................................................................... 219
Chapter 52: Antidysrhythmic Drugs ............................................................................................................................... 226
Chapter 53: Drugs That Help Normalize Cholesterol And Triglyceride Levels.............................................................. 233
Chapter 54: Drugs For Angina Pectoris .......................................................................................................................... 239
Chapter 55: Anticoagulant, Antiplatelet, And Thrombolytic Drugs................................................................................ 245
Chapter 56: Management Of St-Elevation Myocardial Infarction................................................................................... 252
Chapter 57: Drugs For Hemophilia ................................................................................................................................. 256
Chapter 58: Drugs For Deficiency Anemias ................................................................................................................... 260
Chapter 59: Hematopoietic Agents ................................................................................................................................. 266
Chapter 60: Drugs For Diabetes Mellitus........................................................................................................................ 270
Chapter 61: Drugs For Thyroid Disorders ...................................................................................................................... 276
Chapter 62: Drugs Related To Hypothalamic And Pituitary Function ............................................................................ 281
Chapter 63: Drugs For Disorders Of The Adrenal Cortex ............................................................................................... 285
Chapter 64: Estrogens And Progestins: Basic Pharmacology And Noncontraceptiveapplications.................................. 289
Chapter 65: Birth Control ............................................................................................................................................... 293
Chapter 66: Drug Therapy For Infertility ........................................................................................................................ 298
Chapter 67: Drugs That Affect Uterine Function ............................................................................................................ 302
Chapter 68: Androgens ................................................................................................................................................... 307
Chapter 69: Drugs For Erectile Dysfunction And Benign Prostatic Hyperplasia ............................................................ 311
Chapter 70: Review Of The Immune System ................................................................................................................. 315
Chapter 71: Childhood Immunization ............................................................................................................................. 319
Chapter 72: Immunosuppressants ................................................................................................................................... 324
Chapter 73: Antihistamines............................................................................................................................................. 328
Chapter 74: Cyclooxygenase Inhibitors, Nonsteroidal Anti-Inflammatory Drugs Andacetaminophen ........................... 333
Chapter 75: Glucocorticoids In Nonendocrine Disorders................................................................................................ 338
Chapter 76: Drug Therapy For Rheumatoid Arthritis ..................................................................................................... 344
Chapter 77: Drug Therapy For Gout ............................................................................................................................... 347
Chapter 78: Drugs Affecting Calcium Levels And Bone Mineralization ........................................................................ 350
Chapter 79: Drugs For Asthma And Chronic Obstructive Pulmonary Disease ............................................................... 356
Chapter 80: Drugs For Allergic Rhinitis, Cough, And Colds .......................................................................................... 363
Chapter 81: Drugs For Peptic Ulcer Disease................................................................................................................... 368
Chapter 82: Laxatives ..................................................................................................................................................... 373
Chapter 83: Other Gastrointestinal Drugs ....................................................................................................................... 378
Chapter 84: Vitamins ...................................................................................................................................................... 385
, Chapter 85: Drugs For Weight Loss................................................................................................................................ 391
Chapter 86: Complementary And Alternative Therapy ................................................................................................... 396
Chapter 87: Basic Principles Of Antimicrobial Therapy ................................................................................................. 399
Chapter 88: Drugs That Weaken The Bacterial Cell Wall I: Penicillins ......................................................................... 404
Chapter 89: Drugs That Weaken The Bacterial Cell Wall Ii: Other Drugs ..................................................................... 409
Chapter 90: Bacteriostatic Inhibitors Of Protein Synthesis: Tetracyclines, Macrolides, Andothers ................................ 413
Chapter 91: Aminoglycosides: Bactericidal Inhibitors Of Protein Synthesis .................................................................. 421
Chapter 92: Sulfonamides And Trimethoprim ................................................................................................................ 427
Chapter 93: Drug Therapy For Urinary Tract Infections ................................................................................................. 431
Chapter 94: Antimycobacterial Agents ........................................................................................................................... 437
Chapter 95: Miscellaneous Antibacterial Drugs .............................................................................................................. 444
Chapter 96: Antifungal Agents ....................................................................................................................................... 448
Chapter 97: Antiviral Agents I: Drugs For Non-Hiv Viral Infections ............................................................................. 455
Chapter 98: Antiviral Agents Ii: Drugs For Hiv Infection And Related Opportunisticinfections .................................... 460
Chapter 99: Drug Therapy For Sexually Transmitted Diseases ...................................................................................... 465
Chapter 100: Antiseptics And Disinfectants.................................................................................................................... 469
Chapter 101: Anthelmintics ............................................................................................................................................ 473
Chapter 102: Antiprotozoal Drugs I: Antimalarial Agents .............................................................................................. 476
Chapter 103: Antiprotozoal Drugs Ii: Miscellaneous Agents .......................................................................................... 481
Chapter 104: Ectoparasiticides ........................................................................................................................................ 483
Chapter 105: Basic Principles Of Cancer Chemotherapy................................................................................................ 487
Chapter 106: Anticancer Drugs I: Cytotoxic Agents ....................................................................................................... 493
Chapter 107: Anticancer Drugs Ii: Noncytotoxic Agents................................................................................................ 498
Chapter 108: Drugs For The Eye .................................................................................................................................... 502
Chapter 109: Drugs For The Skin ................................................................................................................................... 507
Chapter 110: Drugs For The Ear ..................................................................................................................................... 514
Chapter 111: Management Of Poisoning ........................................................................................................................ 519
Chapter 112: Potential Weapons Of Biologic, Radiologic, And Chemical Terrorism ..................................................... 523