Multiple Sclerosis Part 1 Exam 1 with
verified solutions
What is Multiple Sclerosis?
| | |
A. A disease in which the immune system eats away at the protective
| | | | | | | | | | | |
covering of nerves.
| | |
B. A Chronic, inflammatory, demyelinating Disease of the CNS (brain +
| | | | | | | | | |
Spinal Cord), that leads to axonal and neuronal loss.
| | | | | | | | | |
C. Axonal damage that accumulates w/ disease progression and
| | | | | | | |
results in delay and conduction blocks of electrical potential along
| | | | | | | | | |
CNS pathways.
| |
D All of the above - correct answer -D
| | | | | | | |
T/F Men is twice as likely to be diagnosed with MS compared to
| | | | | | | | | | | |
women - correct answer -F
| | | | |
T/F Onset of MS is usually between 15 and 50yrs with a peak onset at
| | | | | | | | | | | | | |
30yrs old - correct answer -T
| | | | | |
,T/F MS affects predominately African Americans. There's a 50% lower
| | | | | | | | |
risk factor amongst Caucasions, Asians, and and all the -sians - correct
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answer -F
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Medium Frequency areas that has MS includes:
| | | | | |
A. Asia
|
B. African
|
C. Northern US & Europe
| | | |
D. Southern US & Europe
| | | |
E. South America - correct answer -D
| | | | | |
High Frequency areas that has MS includes all of the following except:
| | | | | | | | | | |
A. Southern Canada and Australia
| | | |
B. Scandinavian countries and New Zealand
| | | | |
C. Northern US & Europe
| | | |
D. Southern US & Europe
| | | |
E. Both A and D - correct answer -D
| | | | | | | |
,It is hypothesized that MS is related to be a autoimmune condition
| | | | | | | | | | |
|that is induced by a viral or other infectious agent. Which of the
| | | | | | | | | | | |
|following are linked to MS? | | | |
A All of the below
| | | |
B Herpes
|
C Chlamydial Pneumonia
| |
D Measles
|
E Epstein-Barr
|
F Only B, C, D - correct answer -A
| | | | | | | |
T/F Most pt with MS may become stable and not have any sx. But
| | | | | | | | | | | | |
Flare up can occur. These relapses are often precipitated by Viral
| | | | | | | | | | |
infections up to 33% of the time. - correct answer -T
| | | | | | | | | | |
T/F Although not inherited, there may be a genetic susceptibility to
| | | | | | | | | |
immune system dysfunction - correct answer -T
| | | | | | |
Put these in the correct order for the pathophysiology of MS.
| | | | | | | | | |
A. Demyelination occurs + local inflammation
| | | | |
B. Immune response is triggered (T-lymphocytes, macrophages,
| | | | | |
immunoglobulins)
|
C. Glial Scars results from Gliosis (proliferation of neuroglial tissue)
| | | | | | | | |
, D. loss of normal nerve conduction = loss of function
| | | | | | | | | |
E. Axons get interrupted = under goes degeneration
| | | | | | |
F. BBB fails (T-lymphocytes infiltrates and attack myelin sheath)
| | | | | | | |
A) ABC DEF
| |
B) BAC DEF
| |
C) B FACED
| |
D) DEAF BC - correct answer -B FACED
| | | | | | |
T/F It is very hard to diagnosis MS, due to no specific tests to diagnose
| | | | | | | | | | | | | |
MS and most pts have intermittent sx and some do not. - correct
| | | | | | | | | | | | |
answer -T
| |
T/F Lumbar puncturing is a method used to examine pt's with MS.
| | | | | | | | | | |
They take the pt's CSF to look for specific markers such as
| | | | | | | | | | | |
oligoclocal/IgG bands. - correct answer -T
| | | | | |
T/F MDs can use contrast dye to look at MRI changes. The dye is used
| | | | | | | | | | | | | |
to identify plaques in the CNS of pt's with MS which is typically found
| | | | | | | | | | | | | |
in 95% of cases - correct answer -T
| | | | | | | |
The Three recommended clinical Dx for MS includes:
| | | | | | |
verified solutions
What is Multiple Sclerosis?
| | |
A. A disease in which the immune system eats away at the protective
| | | | | | | | | | | |
covering of nerves.
| | |
B. A Chronic, inflammatory, demyelinating Disease of the CNS (brain +
| | | | | | | | | |
Spinal Cord), that leads to axonal and neuronal loss.
| | | | | | | | | |
C. Axonal damage that accumulates w/ disease progression and
| | | | | | | |
results in delay and conduction blocks of electrical potential along
| | | | | | | | | |
CNS pathways.
| |
D All of the above - correct answer -D
| | | | | | | |
T/F Men is twice as likely to be diagnosed with MS compared to
| | | | | | | | | | | |
women - correct answer -F
| | | | |
T/F Onset of MS is usually between 15 and 50yrs with a peak onset at
| | | | | | | | | | | | | |
30yrs old - correct answer -T
| | | | | |
,T/F MS affects predominately African Americans. There's a 50% lower
| | | | | | | | |
risk factor amongst Caucasions, Asians, and and all the -sians - correct
| | | | | | | | | | | |
answer -F
| |
Medium Frequency areas that has MS includes:
| | | | | |
A. Asia
|
B. African
|
C. Northern US & Europe
| | | |
D. Southern US & Europe
| | | |
E. South America - correct answer -D
| | | | | |
High Frequency areas that has MS includes all of the following except:
| | | | | | | | | | |
A. Southern Canada and Australia
| | | |
B. Scandinavian countries and New Zealand
| | | | |
C. Northern US & Europe
| | | |
D. Southern US & Europe
| | | |
E. Both A and D - correct answer -D
| | | | | | | |
,It is hypothesized that MS is related to be a autoimmune condition
| | | | | | | | | | |
|that is induced by a viral or other infectious agent. Which of the
| | | | | | | | | | | |
|following are linked to MS? | | | |
A All of the below
| | | |
B Herpes
|
C Chlamydial Pneumonia
| |
D Measles
|
E Epstein-Barr
|
F Only B, C, D - correct answer -A
| | | | | | | |
T/F Most pt with MS may become stable and not have any sx. But
| | | | | | | | | | | | |
Flare up can occur. These relapses are often precipitated by Viral
| | | | | | | | | | |
infections up to 33% of the time. - correct answer -T
| | | | | | | | | | |
T/F Although not inherited, there may be a genetic susceptibility to
| | | | | | | | | |
immune system dysfunction - correct answer -T
| | | | | | |
Put these in the correct order for the pathophysiology of MS.
| | | | | | | | | |
A. Demyelination occurs + local inflammation
| | | | |
B. Immune response is triggered (T-lymphocytes, macrophages,
| | | | | |
immunoglobulins)
|
C. Glial Scars results from Gliosis (proliferation of neuroglial tissue)
| | | | | | | | |
, D. loss of normal nerve conduction = loss of function
| | | | | | | | | |
E. Axons get interrupted = under goes degeneration
| | | | | | |
F. BBB fails (T-lymphocytes infiltrates and attack myelin sheath)
| | | | | | | |
A) ABC DEF
| |
B) BAC DEF
| |
C) B FACED
| |
D) DEAF BC - correct answer -B FACED
| | | | | | |
T/F It is very hard to diagnosis MS, due to no specific tests to diagnose
| | | | | | | | | | | | | |
MS and most pts have intermittent sx and some do not. - correct
| | | | | | | | | | | | |
answer -T
| |
T/F Lumbar puncturing is a method used to examine pt's with MS.
| | | | | | | | | | |
They take the pt's CSF to look for specific markers such as
| | | | | | | | | | | |
oligoclocal/IgG bands. - correct answer -T
| | | | | |
T/F MDs can use contrast dye to look at MRI changes. The dye is used
| | | | | | | | | | | | | |
to identify plaques in the CNS of pt's with MS which is typically found
| | | | | | | | | | | | | |
in 95% of cases - correct answer -T
| | | | | | | |
The Three recommended clinical Dx for MS includes:
| | | | | | |
