CHAPTER 26: ANTIBACTERIALS MCCUISTION:
PHARMACOLOGY: A PATIENT-CENTERED NURSING
PROCESS APPROACH, 10TH EDITION QUESTIONS |
TESTED AND PROVEN ANSWERS | LATEST UPDATE
2024/2025 100% (GRADE A+)
1. The nurse is caring for a patient who is receiving an intravenous antibiotic. The nurse notes that
the provider has ordered serum drug peak and trough levels. The nurse understands that these
tests are necessary for which type of drugs?
a. Drugs with a broad spectrum
b. Drugs with a narrow spectrum
c. Drugs with a broad therapeutic index
d. Drugs with a narrow therapeutic index
Ans>> ANS: D
Medications with a narrow therapeutic index have a limited range between the therapeutic dose
and a toxic dose. It is important to monitor these medications closely by evaluating regular serum
peak and trough levels.
1
,2. The nurse is caring for a patient who is receiving an intravenous antibiotic. The patient has a
serum drug trough of 1.5 mcg/mL. The normal trough for this drug is 1.7 to 2.2 mcg/mL.
What will the nurse expect the patient to experience?
a. Inadequate therapeutic effects
b. Increased risk for superinfection
c. Excessive adverse effects
d. Signs of drug toxicity
Ans>> ANS: A
Low peak levels indicate that the medication is below the therapeutic level. They do not indicate
altered risk for superinfection. Because drug levels are lower than indicated it would not be
expected to see excessive adverse effects or signs of drug toxicity.
3. The nurse is teaching a nursing student about the minimal effective concentration (MEC) of
antibiotics. Which statement by the nursing student indicates understanding of this concept?
a. "A serum drug level greater than the MEC ensures that the drug is bacteriostatic.
2
,b. "A serum drug level greater than the MEC broadens the spectrum of the drug."
c. "A serum drug level greater than the MEC is sufficient to halt the growth of the microorganism."
d. "A serum drug level greater than the MEC increases the therapeutic index."
Ans>> ANS: C
4. The nurse is caring for a patient who has recurrent urinary tract infections. The patient's current
infection is not responding to an antibiotic that has been used successfully several times in the
past. The nurse understands that this is most likely due to:
a. acquired bacterial resistance.
b.cross-resistance.
c. inherent bacterial resistance.
d. transferred resistance.
Ans>> ANS: A
Acquired resistance occurs when an organism has been exposed to the antibacterial drug and
becomes resistant over time. Cross-resistance occurs when an organism that is resistant to one drug
is also resistant to another. Inherent resistance occurs without previous exposure to the drug.
3
, Transferred resistance occurs when the resistant genes of one organism are passed to another
organism.
5. The nurse is preparing to administer amoxicillin (Amoxil) to a patient and learns that the
patient previously experienced a rash when taking penicillin. Which action will the nurse take?
a. Administer the amoxicillin and have epinephrine available.
b. Ask the provider to order an antihistamine.
c. Contact the provider to discuss using a different antibiotic.
d. Request an order for a beta-lactamase resistant drug.
Ans>> ANS: C
Patients who have previously experienced manifestations of allergy to a penicillin should not use
penicillins again unless necessary. The nurse should contact the provider to discuss using another
antibiotic from a different class. Epinephrine and antihistamines are useful when patients are
experiencing allergic reactions, depending on severity.
4
PHARMACOLOGY: A PATIENT-CENTERED NURSING
PROCESS APPROACH, 10TH EDITION QUESTIONS |
TESTED AND PROVEN ANSWERS | LATEST UPDATE
2024/2025 100% (GRADE A+)
1. The nurse is caring for a patient who is receiving an intravenous antibiotic. The nurse notes that
the provider has ordered serum drug peak and trough levels. The nurse understands that these
tests are necessary for which type of drugs?
a. Drugs with a broad spectrum
b. Drugs with a narrow spectrum
c. Drugs with a broad therapeutic index
d. Drugs with a narrow therapeutic index
Ans>> ANS: D
Medications with a narrow therapeutic index have a limited range between the therapeutic dose
and a toxic dose. It is important to monitor these medications closely by evaluating regular serum
peak and trough levels.
1
,2. The nurse is caring for a patient who is receiving an intravenous antibiotic. The patient has a
serum drug trough of 1.5 mcg/mL. The normal trough for this drug is 1.7 to 2.2 mcg/mL.
What will the nurse expect the patient to experience?
a. Inadequate therapeutic effects
b. Increased risk for superinfection
c. Excessive adverse effects
d. Signs of drug toxicity
Ans>> ANS: A
Low peak levels indicate that the medication is below the therapeutic level. They do not indicate
altered risk for superinfection. Because drug levels are lower than indicated it would not be
expected to see excessive adverse effects or signs of drug toxicity.
3. The nurse is teaching a nursing student about the minimal effective concentration (MEC) of
antibiotics. Which statement by the nursing student indicates understanding of this concept?
a. "A serum drug level greater than the MEC ensures that the drug is bacteriostatic.
2
,b. "A serum drug level greater than the MEC broadens the spectrum of the drug."
c. "A serum drug level greater than the MEC is sufficient to halt the growth of the microorganism."
d. "A serum drug level greater than the MEC increases the therapeutic index."
Ans>> ANS: C
4. The nurse is caring for a patient who has recurrent urinary tract infections. The patient's current
infection is not responding to an antibiotic that has been used successfully several times in the
past. The nurse understands that this is most likely due to:
a. acquired bacterial resistance.
b.cross-resistance.
c. inherent bacterial resistance.
d. transferred resistance.
Ans>> ANS: A
Acquired resistance occurs when an organism has been exposed to the antibacterial drug and
becomes resistant over time. Cross-resistance occurs when an organism that is resistant to one drug
is also resistant to another. Inherent resistance occurs without previous exposure to the drug.
3
, Transferred resistance occurs when the resistant genes of one organism are passed to another
organism.
5. The nurse is preparing to administer amoxicillin (Amoxil) to a patient and learns that the
patient previously experienced a rash when taking penicillin. Which action will the nurse take?
a. Administer the amoxicillin and have epinephrine available.
b. Ask the provider to order an antihistamine.
c. Contact the provider to discuss using a different antibiotic.
d. Request an order for a beta-lactamase resistant drug.
Ans>> ANS: C
Patients who have previously experienced manifestations of allergy to a penicillin should not use
penicillins again unless necessary. The nurse should contact the provider to discuss using another
antibiotic from a different class. Epinephrine and antihistamines are useful when patients are
experiencing allergic reactions, depending on severity.
4
