NURS 660: PSYCHOPHARM QUESTIONS | TESTED
AND PROVEN ANSWERS | LATEST UPDATE
2024/2025 100% (GRADE A+)
Minimum ANC level to prescribe Clozapine, general population:
Ans>> 1,500 μL
Severe Neutropenia
Ans>> < 500μL
Moderate Neutropenia
Ans>> 500-999μL
Mild Neutropenia
Ans>> 1000-1499μL
BEN patients: Normal ANC range for Clozaril
Ans>> ≥1,000 μL
1
,Clozaril BEN patient: severe neutropenia
Ans>> <500 μL
BEN neutropenia
Ans>> 500-999 μL
Lower ANC threshold for starting clozapine: General population
Ans>> ≥1,500/μL
Lower ANC threshold for starting clozapine: Benign ethnic neutropenia (BEN)
Ans>> 1,000/μL
Medical emergencies when prescribing anti-psychotics
Ans>> - NMS
- Agranulocytosis
2
,- Serotonin Syndrome
Clinical findings in agranulocytosis
Ans>>
Clozaril: most likely side effect if pt develops fever within 6 weeks
Ans>> Myocarditis
Clozaril: if pt develops fever within 6 weeks order a ______, _________ and _______.
Ans>> EKG, CRP, Troponin, as this is likely due to myocarditis
Common complaints in patients with neutropenia:
F,P, U, P
Ans>> - Fever (low grade)
- painful swallowing (odynophagia)
- URI (sinusitis, otitis, cough)
- Perirectal pain/irritation
3
, Symptoms of neuroleptic malignant syndrome (NMS):
Ans>> - High fever
- Tachycardia/irregular pulse
- Increased respiratory rate
- Muscle Rigidity
- altered mental status
Off label TX for NMS
Ans>> Amantadine (SYMMETREL)
Serotonin Syndrome onset:
Ans>> -24 hours of combining antidepressants
Serotonin Syndrome Cardinal features
Ans>> - Myoclonic jerks
- Hyperreflexia
4
AND PROVEN ANSWERS | LATEST UPDATE
2024/2025 100% (GRADE A+)
Minimum ANC level to prescribe Clozapine, general population:
Ans>> 1,500 μL
Severe Neutropenia
Ans>> < 500μL
Moderate Neutropenia
Ans>> 500-999μL
Mild Neutropenia
Ans>> 1000-1499μL
BEN patients: Normal ANC range for Clozaril
Ans>> ≥1,000 μL
1
,Clozaril BEN patient: severe neutropenia
Ans>> <500 μL
BEN neutropenia
Ans>> 500-999 μL
Lower ANC threshold for starting clozapine: General population
Ans>> ≥1,500/μL
Lower ANC threshold for starting clozapine: Benign ethnic neutropenia (BEN)
Ans>> 1,000/μL
Medical emergencies when prescribing anti-psychotics
Ans>> - NMS
- Agranulocytosis
2
,- Serotonin Syndrome
Clinical findings in agranulocytosis
Ans>>
Clozaril: most likely side effect if pt develops fever within 6 weeks
Ans>> Myocarditis
Clozaril: if pt develops fever within 6 weeks order a ______, _________ and _______.
Ans>> EKG, CRP, Troponin, as this is likely due to myocarditis
Common complaints in patients with neutropenia:
F,P, U, P
Ans>> - Fever (low grade)
- painful swallowing (odynophagia)
- URI (sinusitis, otitis, cough)
- Perirectal pain/irritation
3
, Symptoms of neuroleptic malignant syndrome (NMS):
Ans>> - High fever
- Tachycardia/irregular pulse
- Increased respiratory rate
- Muscle Rigidity
- altered mental status
Off label TX for NMS
Ans>> Amantadine (SYMMETREL)
Serotonin Syndrome onset:
Ans>> -24 hours of combining antidepressants
Serotonin Syndrome Cardinal features
Ans>> - Myoclonic jerks
- Hyperreflexia
4