Benign Prostatic Hypertension
(BPH) Latest Exam Fully Solved.
Which medication used for the treatment of BPH is contraindicated with isosorbide dinitrate? - Answer
Tadalafil - PDE-5 inhibitor is C/I with nitrates and riociguat (drug used for PAH)
Patients with BPH should be counseled to avoid which of the following products that can worsen
symptoms? SATA - Answer Testosteron
Diphenhydramine
Pseudoephedrine
Caffeine
NOT: Ibuprofen
* Meds/supplements that cause urinary retention (ie. antihistamines), vasoconstriction due to alpha-
agonist activity (ie. decongestants), diuresis or stimulation of prostate growth can worsen BPH symptoms
A male patient with prostate enlargement was prescribed Cardura. What counseling points should be
provided? SATA - Answer It is important to stand up slowly after sitting
Take the medication at bedtime
The dose should be slowly increased
* Non-selective alpha-1 blockers should be taken at bedtime and titrated slowly to reduce orthostasis
* Cardura XL can leave a ghost tablet that is seen in the stool but not Cardura (IR)
Which best describes the mechanism of action of Proscar? - Answer Inhibits 5 alpha-reductase
JB takes tadalafil for erectile dysfunction and metformin and sitagliptin for type 2 diabetes. Which side
effect is he most at risk for if tamsulosin is added for BPH? - Answer Hypotension
* Selective alpha-1A blockers cause less dizziness and BP changes than the non-selective agents but
additive effects can occur, which warrants caution
* If tadalafil is being used for BPH, then an alpha-1 blocker is not recommended
(BPH) Latest Exam Fully Solved.
Which medication used for the treatment of BPH is contraindicated with isosorbide dinitrate? - Answer
Tadalafil - PDE-5 inhibitor is C/I with nitrates and riociguat (drug used for PAH)
Patients with BPH should be counseled to avoid which of the following products that can worsen
symptoms? SATA - Answer Testosteron
Diphenhydramine
Pseudoephedrine
Caffeine
NOT: Ibuprofen
* Meds/supplements that cause urinary retention (ie. antihistamines), vasoconstriction due to alpha-
agonist activity (ie. decongestants), diuresis or stimulation of prostate growth can worsen BPH symptoms
A male patient with prostate enlargement was prescribed Cardura. What counseling points should be
provided? SATA - Answer It is important to stand up slowly after sitting
Take the medication at bedtime
The dose should be slowly increased
* Non-selective alpha-1 blockers should be taken at bedtime and titrated slowly to reduce orthostasis
* Cardura XL can leave a ghost tablet that is seen in the stool but not Cardura (IR)
Which best describes the mechanism of action of Proscar? - Answer Inhibits 5 alpha-reductase
JB takes tadalafil for erectile dysfunction and metformin and sitagliptin for type 2 diabetes. Which side
effect is he most at risk for if tamsulosin is added for BPH? - Answer Hypotension
* Selective alpha-1A blockers cause less dizziness and BP changes than the non-selective agents but
additive effects can occur, which warrants caution
* If tadalafil is being used for BPH, then an alpha-1 blocker is not recommended
