CPHON CANCERS TEST LATEST VERSION
Four types of non-Hodgkins lymphoma - ANSWER Lymphoblastic lymphoma
Burkitt's lymphoma
Diffuse large B cell lymphoma
Anaplastic large cell lymphoma
Lymphoblastic lymphoma - ANSWER Mostly T cell
All ages
70% medical mass
Burkitt's lymphoma - ANSWER 5-10 y.o
B cell
Abdomen and pelvis
Rapidly enlarging mass
Endemic BL in Africa (EBV and jaw)
Diffuse large cell lymphoma (DLCL) - ANSWER Mass is favorable
2/3 present with advanced diagnosis (abdomen)
Lymph nodes more common than BL
ALCL-
ANSWER Older children
Kidney shaped
T cell antigen
Anaplastic lymphoma kinase (ALK) in 90%
, Non- hodgkins S/S-
ANSWER 2/3 present with advanced mets
CNS rare
Diagnosis-
ANSWER Burkitt's lymphoma fastest growing
BMA 25% blasts= ALL
Non Hodgkins staging-
ANSWER I- 1 tumor or node
II- 2+ on same side of diaphragm
III- 2+ on both sides of diaphragm
IV- BM or CNS
Non Hodgkins Lymphoma treatment - ANSWER Surgery- biopsy for staging
Chemo and CNS prophylactically
Rituximab CD20
Recurrent- HSCT (not for anaplastic large cell lymphoma)
Hodgkin's lymphoma - ANSWER Lymphatic system
Reed sternberg cells (owl eyes)
80% painless adenopathy- firm and rubbery
2/3 with medistanial mass and tracheal/bronchial compression
Subtypes of HL - ANSWER Classic HL (reed sternberg cells)
Nodular lymphocyte predominant HL
Four types of non-Hodgkins lymphoma - ANSWER Lymphoblastic lymphoma
Burkitt's lymphoma
Diffuse large B cell lymphoma
Anaplastic large cell lymphoma
Lymphoblastic lymphoma - ANSWER Mostly T cell
All ages
70% medical mass
Burkitt's lymphoma - ANSWER 5-10 y.o
B cell
Abdomen and pelvis
Rapidly enlarging mass
Endemic BL in Africa (EBV and jaw)
Diffuse large cell lymphoma (DLCL) - ANSWER Mass is favorable
2/3 present with advanced diagnosis (abdomen)
Lymph nodes more common than BL
ALCL-
ANSWER Older children
Kidney shaped
T cell antigen
Anaplastic lymphoma kinase (ALK) in 90%
, Non- hodgkins S/S-
ANSWER 2/3 present with advanced mets
CNS rare
Diagnosis-
ANSWER Burkitt's lymphoma fastest growing
BMA 25% blasts= ALL
Non Hodgkins staging-
ANSWER I- 1 tumor or node
II- 2+ on same side of diaphragm
III- 2+ on both sides of diaphragm
IV- BM or CNS
Non Hodgkins Lymphoma treatment - ANSWER Surgery- biopsy for staging
Chemo and CNS prophylactically
Rituximab CD20
Recurrent- HSCT (not for anaplastic large cell lymphoma)
Hodgkin's lymphoma - ANSWER Lymphatic system
Reed sternberg cells (owl eyes)
80% painless adenopathy- firm and rubbery
2/3 with medistanial mass and tracheal/bronchial compression
Subtypes of HL - ANSWER Classic HL (reed sternberg cells)
Nodular lymphocyte predominant HL
