NGR 6172 Male GU with 100%
correct answers (latest update)
What is the benefit provided by 5 alpha reductase inhibitors in treating
BPH? - answer 5 alpha dihydro-testosterone (DHT) is needed for prostate
growth, 5 alpha reductase metabolizes testosterone to its active form in
the prostate gland, liver, and skin; 5 alpha reductase inhibitor reduces this
conversion and reduces actual prostate growth/size (6-12 months to see
effect)
Warning: can increase risk of high-grade prostate cancer while taking
these
Saw palmetto also acts as 5a-reductase inhibitor
Which male GU agent includes warnings against pregnant women touching
the medication? - answer 5 alpha reductase inhibitors ( finasteride,
dutasteride) are Pregnacy X, bc they block testosterone, and can cause
abnormalities in male fetuses.
Which BPH medicines are the most selective for the prostate and which
are better for managing hypertension PLUS prostatic hypertrophy? -
answer Selective agents:flomax, uroxatrol, specific to alpha 1 adrenergic
receptor of the prostate and do not effect BP as much
HTN + BPH meds: 2nd-generation alpha1-receptor inhibitors include
doxazosin and terazosin. Because they reduce blood pressure, they are
FDA-approved for both hypertension and BPH
Describe the mechanism of action of the alpha-1 adrenergic antagonists. -
answer Receptor blockers; reduce sympathetic tone, relaxes urethral
stricture, lowers BP, blocks a-1 adrengeric receptors from the arterial;
helps to urinate easier; quicker symptom release, few days to week
correct answers (latest update)
What is the benefit provided by 5 alpha reductase inhibitors in treating
BPH? - answer 5 alpha dihydro-testosterone (DHT) is needed for prostate
growth, 5 alpha reductase metabolizes testosterone to its active form in
the prostate gland, liver, and skin; 5 alpha reductase inhibitor reduces this
conversion and reduces actual prostate growth/size (6-12 months to see
effect)
Warning: can increase risk of high-grade prostate cancer while taking
these
Saw palmetto also acts as 5a-reductase inhibitor
Which male GU agent includes warnings against pregnant women touching
the medication? - answer 5 alpha reductase inhibitors ( finasteride,
dutasteride) are Pregnacy X, bc they block testosterone, and can cause
abnormalities in male fetuses.
Which BPH medicines are the most selective for the prostate and which
are better for managing hypertension PLUS prostatic hypertrophy? -
answer Selective agents:flomax, uroxatrol, specific to alpha 1 adrenergic
receptor of the prostate and do not effect BP as much
HTN + BPH meds: 2nd-generation alpha1-receptor inhibitors include
doxazosin and terazosin. Because they reduce blood pressure, they are
FDA-approved for both hypertension and BPH
Describe the mechanism of action of the alpha-1 adrenergic antagonists. -
answer Receptor blockers; reduce sympathetic tone, relaxes urethral
stricture, lowers BP, blocks a-1 adrengeric receptors from the arterial;
helps to urinate easier; quicker symptom release, few days to week
