RTPP 07 Study Guide With
Complete Solution
Recognize the other terms often used to identify interstitial lung disease ILD
- ANSWER diffuse interstitial lung disease,
fibrotic interstitial lung disease,
pulmonary fibrosis
list major pathological or structural changes associated with interstitial or
fibrosing lung disease - ANSWER Inflammation,
airway changes and secretions,
lymphocyte activity,
scar formation
be able to classify and identify the casual agent for the common interstitial
lung disorders (inorganic) - ANSWER *asbestosis*- crystal like fibers,
*coal workers pneumoconiosis* - silica found in coal is the true inflammatory
agent not the coal it's self. *silicosis* - crystalline, free silica, or silicon dioxide
particles.
be able to classify and identify the casual agent for the common interstitial
,lung disorders (Organic-Hypersensitivity Pneumonitis) - ANSWER The lung
inflammation develops after repeated/prolonged exposure to allergen
Examples-
*Bagassosis* - moldy sugarcane,
*Farmer's Lung* - moldy hay and silage,
*Bird Breeder's Lung* - bird droppings and feathers (Pigeon breeder's lung,
Bird fancier's lung)
be able to classify and identify the casual agent for the common interstitial
lung disorders (therapeutic exposures and illicit drugs) - ANSWER
chemotherapy agents,
prescription drugs,
radiation,
Gold and penicillamine for rheumatoid arthritis also cause ILD,
Oxygen toxicity (long term excessive oxygen administration) is also a cause.
list and briefly describe the most common collagen vascular connective tissue
diseases that frequently cause pulmonary fibrosis - ANSWER *scleroderma* -
chronic hardening and thickening of skin, rare autoimmune disorder, causes
significant scarring in lungs, most common in women of 30-50 years of age
*Rheumatoid Arthritis* - inflammatory joint disease, pleurisy is most
common pulmonary complication, ILD most common in male patients
, *Systemic Lupus Erythematosus (SLE)* - multi-system disorder of joints and
skin, can affect kidneys, lungs, nervous system & heart, pleurisy and
pulmonary infections are common
*Sarcoidosis* - chronic, unknown cause, tubercles in eyes, lungs (almost
always), spleen, liver, skin & lymph glands, known by an increase in all 3
immunoglobulins (IgM, IgG, and IgA). Most common in 10-40 year old
African-American women
.Explain idiopathic interstitial pneumonitis and the two most common types
*(Idiopathic Pulmonary Fibrosis)* - ANSWER *Idiopathic Pulmonary Fibrosis*
- also called: HammanRich syndrome, honeycomb lung, interstitial fibrosis,
interstitial pneumonitis • Pt that does not have a readily identified exposure,
disorder, or genetic cause fall into this category. • Most common in men of
40-70 years of age • Diagnosed by open lung biopsy • Can lead to death in
4-10 years
Explain idiopathic interstitial pneumonitis and the two most common types
*(Cryptogenic Organizing Pneumonia (COP)* - ANSWER *Cryptogenic
Organizing Pneumonia (COP)* - also called bronchiolitis obliterans
organizing pneumonia (BOOP). • connective tissue plugs appear in the small
airways & monocytes invade the surrounding area (organizing), no cause but
associated with connective tissue disease, toxic gas inhalation, & infection.
Describe the basic pathophysiology of the disorders known as pulmonary
vasculatides and Identify wegeners granulomatosis as one - ANSWER Aka
Complete Solution
Recognize the other terms often used to identify interstitial lung disease ILD
- ANSWER diffuse interstitial lung disease,
fibrotic interstitial lung disease,
pulmonary fibrosis
list major pathological or structural changes associated with interstitial or
fibrosing lung disease - ANSWER Inflammation,
airway changes and secretions,
lymphocyte activity,
scar formation
be able to classify and identify the casual agent for the common interstitial
lung disorders (inorganic) - ANSWER *asbestosis*- crystal like fibers,
*coal workers pneumoconiosis* - silica found in coal is the true inflammatory
agent not the coal it's self. *silicosis* - crystalline, free silica, or silicon dioxide
particles.
be able to classify and identify the casual agent for the common interstitial
,lung disorders (Organic-Hypersensitivity Pneumonitis) - ANSWER The lung
inflammation develops after repeated/prolonged exposure to allergen
Examples-
*Bagassosis* - moldy sugarcane,
*Farmer's Lung* - moldy hay and silage,
*Bird Breeder's Lung* - bird droppings and feathers (Pigeon breeder's lung,
Bird fancier's lung)
be able to classify and identify the casual agent for the common interstitial
lung disorders (therapeutic exposures and illicit drugs) - ANSWER
chemotherapy agents,
prescription drugs,
radiation,
Gold and penicillamine for rheumatoid arthritis also cause ILD,
Oxygen toxicity (long term excessive oxygen administration) is also a cause.
list and briefly describe the most common collagen vascular connective tissue
diseases that frequently cause pulmonary fibrosis - ANSWER *scleroderma* -
chronic hardening and thickening of skin, rare autoimmune disorder, causes
significant scarring in lungs, most common in women of 30-50 years of age
*Rheumatoid Arthritis* - inflammatory joint disease, pleurisy is most
common pulmonary complication, ILD most common in male patients
, *Systemic Lupus Erythematosus (SLE)* - multi-system disorder of joints and
skin, can affect kidneys, lungs, nervous system & heart, pleurisy and
pulmonary infections are common
*Sarcoidosis* - chronic, unknown cause, tubercles in eyes, lungs (almost
always), spleen, liver, skin & lymph glands, known by an increase in all 3
immunoglobulins (IgM, IgG, and IgA). Most common in 10-40 year old
African-American women
.Explain idiopathic interstitial pneumonitis and the two most common types
*(Idiopathic Pulmonary Fibrosis)* - ANSWER *Idiopathic Pulmonary Fibrosis*
- also called: HammanRich syndrome, honeycomb lung, interstitial fibrosis,
interstitial pneumonitis • Pt that does not have a readily identified exposure,
disorder, or genetic cause fall into this category. • Most common in men of
40-70 years of age • Diagnosed by open lung biopsy • Can lead to death in
4-10 years
Explain idiopathic interstitial pneumonitis and the two most common types
*(Cryptogenic Organizing Pneumonia (COP)* - ANSWER *Cryptogenic
Organizing Pneumonia (COP)* - also called bronchiolitis obliterans
organizing pneumonia (BOOP). • connective tissue plugs appear in the small
airways & monocytes invade the surrounding area (organizing), no cause but
associated with connective tissue disease, toxic gas inhalation, & infection.
Describe the basic pathophysiology of the disorders known as pulmonary
vasculatides and Identify wegeners granulomatosis as one - ANSWER Aka
