Exam 2: NURS 615/ NURS615 (New 2024/ 2025 Update) Advanced Pharmacotherapeutics Complete Review with Qs & As| 100% Correct| Grade A (Verified Answers) - Maryville

ExamI2:INURSI615/INURS615I(New
Update)IAdvancedI
PharmacotherapeuticsICompleteIReviewI
withIQsI&IAs|I100%ICorrect|IGradeIAI
(VerifiedIAnswers)-IMaryville

QUESTION
WhichImedicationsIinteractIwithIlinezolid?


Answer:
AndrenergicIdrugsI(sympathomimetic—dopamineIandIepinephrine)

Effect:IincreasedIactionIofItheIinteractingIdrug

ReduceIandItitrateIinitialIdosesIofIinteractingIdrug,ImonitorIbloodIpressure
---------------------------------------------
MAOIs

IncreasedIriskIofIserotoninIsyndrome

DiscontinueIinteractingIdrugI2IweeksIbeforeIstartingIlinezolid
I--------------------------------------------
SerotonergicsI(e.g.,ISSRIs)
DevelopmentIofIserotoninIsyndromeI

WatchIforIserotoninIsyndromeIindications.IAvoidIconcurrentIuseIunlessInoIappropriateIalternat
ive.
I-----------------------------------------
TyramineIrichIfoodsIandIdrinks
SignificantlyIincreasedIbloodIpressure

NoIneedItoIdeleteIentirelyIfromIdiet,IbutIquantitiesIofItyramineIeatenIshouldInotIexceedI100m
g/meal

,QUESTION
WhatIisItheIcourseIofItreatmentIwithIdoxycyclineIforItheItreatmentIofILymeIDisease?


Answer:
Doxycycline,I100mgItwiceIdailyIisItheIfirstIlineIdrugIofIchoiceIforIearlyItreatmentIofILymeIdi
sease,IaItickIborneIinfectionIcausedIbyIB.Iburgdorferi.




QUESTION
WhatIareItheImainIsideIeffectsIofIdoxycycline?


Answer:
CanIcauseIphototoxicity,IsoIsunlightIandItanningIlightsIshouldIbeIavoided.IWearIsunscreen,Ihat
s,IandIprotectiveIclothingIifInecessaryItoIbeIinItheIsunIforImoreIthanIaIfewIminutes.IDifferenti
ateIbetweenIoralIandIparenteralIvancomycin




QUESTION
DifferentiateIbetweenIoralIandIparenteralIvancomycin.


Answer:
AbsorptionIofIvancomycinIformItheIGIItractIisIpoor,IalthoughIclinicallyIsignificantIserumIcon
centrationsIhaveIoccurred.IWhenIadministeredIintravenously,IonsetIofIactionIisIrapid,IwithIpea
kIconcentrationsIinI1IhourIandIaIdurationIofIeffectIofIapproximatelyI12Ihours,IdependingIonIr
enalIclearance.IItIisI52%ItoI56%IproteinIboundIandIhasIlessIthanI1%IbioavailabilityIbyItheIor
alIroute.IItsIhalf-
lifeIisI4ItoI6IhoursIinIadultsIandI2ItoI3IhoursIinIchildren.IDistributionIisIwide,IwithI20%ItoI30
%IpenetrationIofItheICSF.ITheIdrugIcrossesItheIplacenta.




QUESTION
WhatIisItheImechanismIofIactionIofIazithromycin?

, Answer:
BindsItoItheIPIsiteIofItheI50SIribosomeIsubunitIofIsusceptibleIorganismsIandImayIinhibitIRN
A-dependentIsynthesisIbyIstimulatingItheIdisassociationIofIpeptidyl-
tRNAIfromIribosomes.ITheseIdrugsIareItypicallyIbacteriostaticIbutImayIbeIbactericidalIdepend
ingIonIdrugIconcentrationsIandItheIbacterialIspeciesItested.IMacrolidesIareIweakIbases,IandIth
eirIactivityIincreasesIinIalkalineImedia.




QUESTION
WhichIantibioticsIblockIbacterialIproteinIproduction?


Answer:
TetracyclinesIinhibitIproteinIsynthesisIbyIreversiblyIbindingItoItheI30SIsubunitIofItheIbacterial
IribosomeIandIpreventingItheIadditionIofIaminoIacidsItoIgrowingIpeptides.




QUESTION
WhatIvitaminIwillIdecreaseIperipheralIneuropathy?


Answer:
VitaminIB12IorIfolateIvitaminIsupplementationIwillIdecreaseIperipheralIneuropathy.




QUESTION
WhatIlabIvaluesIshouldIbeIassessedIwhenIadministeringIvalacyclovir?


Answer:
BUNIandIserumIcreatinineImayIbeIassessedIpriorItoItherapyIinIthoseIwithIriskIfactorsIforIrena
lIimpairmentIandIperiodicallyIduringIprolongedItherapyItoIdetectIchangesIinIrenalIfunction.




QUESTION
WhenIshouldIoseltamivirIphosphateIbeIprescribed?