Chemotherapy Biotherapy Certification
Resources - ANSnccn.Org
cancer.Org
LESSON 1: Cell cycle - ANSg1- increase in size
s- dna replicated
g2- cellular extend and ready to divide
m phase- 2 hours
mitosis - ANS4 tiers, prophase, metaphase, anaphase, telophase
-chemo goals sure factors in the manner
apoptosis - ANSprogrammed mobile death
hematopoiesis - ANSformation of blood cells & how cells differentiate
-myeloid: pre cells mature into RBCs, platelets and WBCs
-lymphoid: pre cells- mature into WBCS
Principles of Biotherapy: p51-95 immunology - ANS-defense against overseas organisms,
homeostasis (spoil aged cells), surveillance
immune responses - ANSinnate: number one line of protection, non particular, no memory
adaptive: secondary line of defence with precise memry
cytokines - ANS-effect boom and differentiation of WBC
-interferons, tumor necrosis elements, growth factos and interleukins
-small protein molecules released by way of cells at some stage in body supplying comunication
among cells of the immune gadget
-ordinary antiboddy manufacturing and characteristic of b cells
vaccines for cancer prevention - ANS-hep B prevents hepatitis and hepatocellular carcinoma
-hpv vaccine
filgrastim aka neupogen - ANSSC or IV to derease contamination in patients with neutropenic
fever associated with myelosuppressive anticancer treatments for nonmyeloid malignancies
tbo-filgramstim/ pegfilgrastim - ANSreduce period of neutroenia in sufferers with non myeloid
malignancies
, palifermin - ANSIV to dec prevalence of oral mucositis in patients with hem malignanies before
BMT
sargramostim - ANSaka leukine - sufferers with AML following chemo to shorten neutrophil
recovery and reduce prevalence of infection
IFN gamma - ANSreduce frequency and severity o infections associated with granulomatous
sickness
aldeleukin - ANStreat renal mobile carcinoma and metastatic cancer
oprevelkin - ANSprevent excessive thrombocytopenia and refuce need for platelet transfusions
in sufferers with nonmyeloid malig
plerixafor - ANSwith filgrastim to mobilize hematopoeitc stem cells for collection from peripheral
blood of sufferers
sipuleucel - ANScastrate resistant prostate most cancers
rituximab - ANSrituxan- remedy of relapsed or refractory low grade follicular b cell NHL_ first line
traetment in combination with chemo in sufferers with response
-can deal with severe rheumatoid arthritis
-may have severe reactions (hypotension, urticaria, angiodema, hypoxia, rigors, dyspnea, chills,
fever, nausea, rash, renal tox)
-premed with tylenol and benadryl
-sluggish infusion to remedy some side effects, side effects reduce with every infusion
immune device - ANS1st line: skin , ucous membrane, intestine plant life
2nd line: phagocytes:
3rd line antibodies, t and b cells
malignant tumor (most cancers) - ANScell strcuture special from figure tissue, mobile division
uncontrolled, loosely adherent, invade neighboring tissue, set up blood vessels
Approaches to remedy - ANScure: prolonged absence of sickness
manage: no in addition increase
and palliation : comfort
neoadjuvant - ANStherapy inside the first step to cut back a tumor before the primary treatment)
surgical procedure is given
-chemo, radiation, hormone therapy
adjuvant - ANStherapy given afer number one treatment to lower danger of cancer coming back
-chemo, radiation, hormone, targeted and biologic remedy
Resources - ANSnccn.Org
cancer.Org
LESSON 1: Cell cycle - ANSg1- increase in size
s- dna replicated
g2- cellular extend and ready to divide
m phase- 2 hours
mitosis - ANS4 tiers, prophase, metaphase, anaphase, telophase
-chemo goals sure factors in the manner
apoptosis - ANSprogrammed mobile death
hematopoiesis - ANSformation of blood cells & how cells differentiate
-myeloid: pre cells mature into RBCs, platelets and WBCs
-lymphoid: pre cells- mature into WBCS
Principles of Biotherapy: p51-95 immunology - ANS-defense against overseas organisms,
homeostasis (spoil aged cells), surveillance
immune responses - ANSinnate: number one line of protection, non particular, no memory
adaptive: secondary line of defence with precise memry
cytokines - ANS-effect boom and differentiation of WBC
-interferons, tumor necrosis elements, growth factos and interleukins
-small protein molecules released by way of cells at some stage in body supplying comunication
among cells of the immune gadget
-ordinary antiboddy manufacturing and characteristic of b cells
vaccines for cancer prevention - ANS-hep B prevents hepatitis and hepatocellular carcinoma
-hpv vaccine
filgrastim aka neupogen - ANSSC or IV to derease contamination in patients with neutropenic
fever associated with myelosuppressive anticancer treatments for nonmyeloid malignancies
tbo-filgramstim/ pegfilgrastim - ANSreduce period of neutroenia in sufferers with non myeloid
malignancies
, palifermin - ANSIV to dec prevalence of oral mucositis in patients with hem malignanies before
BMT
sargramostim - ANSaka leukine - sufferers with AML following chemo to shorten neutrophil
recovery and reduce prevalence of infection
IFN gamma - ANSreduce frequency and severity o infections associated with granulomatous
sickness
aldeleukin - ANStreat renal mobile carcinoma and metastatic cancer
oprevelkin - ANSprevent excessive thrombocytopenia and refuce need for platelet transfusions
in sufferers with nonmyeloid malig
plerixafor - ANSwith filgrastim to mobilize hematopoeitc stem cells for collection from peripheral
blood of sufferers
sipuleucel - ANScastrate resistant prostate most cancers
rituximab - ANSrituxan- remedy of relapsed or refractory low grade follicular b cell NHL_ first line
traetment in combination with chemo in sufferers with response
-can deal with severe rheumatoid arthritis
-may have severe reactions (hypotension, urticaria, angiodema, hypoxia, rigors, dyspnea, chills,
fever, nausea, rash, renal tox)
-premed with tylenol and benadryl
-sluggish infusion to remedy some side effects, side effects reduce with every infusion
immune device - ANS1st line: skin , ucous membrane, intestine plant life
2nd line: phagocytes:
3rd line antibodies, t and b cells
malignant tumor (most cancers) - ANScell strcuture special from figure tissue, mobile division
uncontrolled, loosely adherent, invade neighboring tissue, set up blood vessels
Approaches to remedy - ANScure: prolonged absence of sickness
manage: no in addition increase
and palliation : comfort
neoadjuvant - ANStherapy inside the first step to cut back a tumor before the primary treatment)
surgical procedure is given
-chemo, radiation, hormone therapy
adjuvant - ANStherapy given afer number one treatment to lower danger of cancer coming back
-chemo, radiation, hormone, targeted and biologic remedy
