EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024
NU 578 Spring 2017 Unit 4 Study Guide
Treatments for Hypothyroidism - Answer✔✔-Levothyroxine (T4), Liothyronine (T3), Liotrix,
Thyroid (Desiccated)
Levothyroxine (T4) - Answer✔✔-Drug of choice for patients who require thyroid hormone
replacement. Absorption is reduced by food. Most of the does is converted to T3. Highly bound
to protein and half life is about 7 days. Used for cretinism, myxedema coma, simple goiter, and
primary hypothyroidism in adults and children. With overdose s/s of thyroid toxicosis may
result. Chronic overdose is associated with accelerated bone loss and increased risk of atrial
fibrillation, especially in older adults.
What are the signs and symptoms of thyrotoxicosis? - Answer✔✔-Tachycardia, angina, tremor,
nervousness, insomnia, hyperthermia, heat intolerance, and sweating.
Drugs that reduce Levothyroxine Absorption - Answer✔✔-Histamine (H2) receptor blockers like
cimetidine (Tagamet), Proton pump inhibitors like lansoprazole (Prevacid), Sucralfate (Carafate),
Cholestyramine (Questran), Colestipol (Colestid), Aluminum-containing antacid, Calcium
supplements, Iron supplements, Magnesium salts, Orlistat (Xenical). Separate administration of
(blank) by 4 hours .
Page 1/12
, EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024
Drugs that accelerate Levothyroxine Metabolism - Answer✔✔-Phenytoin, Carbamazepine
(Tegretol, Carbatrol), Rifampin (Rifadin), Sertraline (Zoloft) and Phenobarbital. Patient's may
need an increase in (blank) medication if taking these drugs.
What happens when Levothyroxine and Warfarin are taken together ? - Answer✔✔-
Levothyroxine (blank) the degradation of vitamin K-dependent clotting factors which results in
(blank) effects of warfarin. Dosage of Warfarin may need to be (blank)
a.) accelerates, enhanced, reduced
b.) slows, decreased, increased
c. No change in Warfarin
answer is a.
What happens when Levothyroxine and Catecholamines are taken together? - Answer✔✔-
Thyroid hormones (blank) cardiac responsive to catecholamines (epinephrine, dopamine,
dobutamine) thereby (blank) the risk of catecholamine induced dysrhythmias.
a.) decrease, reducing,
b. increase, increasing
c. No change in medication
answer is b.
Levothyroxine can (blank) requirements for insulin and digoxin and dosages may need to be
(blank) - Answer✔✔-a.) decrease, reduced
Page 2/12
NU 578 Spring 2017 Unit 4 Study Guide
Treatments for Hypothyroidism - Answer✔✔-Levothyroxine (T4), Liothyronine (T3), Liotrix,
Thyroid (Desiccated)
Levothyroxine (T4) - Answer✔✔-Drug of choice for patients who require thyroid hormone
replacement. Absorption is reduced by food. Most of the does is converted to T3. Highly bound
to protein and half life is about 7 days. Used for cretinism, myxedema coma, simple goiter, and
primary hypothyroidism in adults and children. With overdose s/s of thyroid toxicosis may
result. Chronic overdose is associated with accelerated bone loss and increased risk of atrial
fibrillation, especially in older adults.
What are the signs and symptoms of thyrotoxicosis? - Answer✔✔-Tachycardia, angina, tremor,
nervousness, insomnia, hyperthermia, heat intolerance, and sweating.
Drugs that reduce Levothyroxine Absorption - Answer✔✔-Histamine (H2) receptor blockers like
cimetidine (Tagamet), Proton pump inhibitors like lansoprazole (Prevacid), Sucralfate (Carafate),
Cholestyramine (Questran), Colestipol (Colestid), Aluminum-containing antacid, Calcium
supplements, Iron supplements, Magnesium salts, Orlistat (Xenical). Separate administration of
(blank) by 4 hours .
Page 1/12
, EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024
Drugs that accelerate Levothyroxine Metabolism - Answer✔✔-Phenytoin, Carbamazepine
(Tegretol, Carbatrol), Rifampin (Rifadin), Sertraline (Zoloft) and Phenobarbital. Patient's may
need an increase in (blank) medication if taking these drugs.
What happens when Levothyroxine and Warfarin are taken together ? - Answer✔✔-
Levothyroxine (blank) the degradation of vitamin K-dependent clotting factors which results in
(blank) effects of warfarin. Dosage of Warfarin may need to be (blank)
a.) accelerates, enhanced, reduced
b.) slows, decreased, increased
c. No change in Warfarin
answer is a.
What happens when Levothyroxine and Catecholamines are taken together? - Answer✔✔-
Thyroid hormones (blank) cardiac responsive to catecholamines (epinephrine, dopamine,
dobutamine) thereby (blank) the risk of catecholamine induced dysrhythmias.
a.) decrease, reducing,
b. increase, increasing
c. No change in medication
answer is b.
Levothyroxine can (blank) requirements for insulin and digoxin and dosages may need to be
(blank) - Answer✔✔-a.) decrease, reduced
Page 2/12
