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CMN 568 Unit 3 Study Guide with Complete Solutions

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CMN 568 Unit 3 Study Guide with Complete Solutions What are the 3 characteristics of Asthma - Answer-Bronchoconstriction Airway Inflammation Reversible airflow limitation Which inhaled anticholinergic is best used for asthma pt. w/an intolerance to beta agonist or w/ bronchospasms due to beta blocker meds? - Answer-Ipratropium Bromide What is the primary tx for pt. w/moderate to severe asthma exacerbations who do not respond promptly and completely to SABA? - Answer-Systemic Corticosteroids Which bacterial infections predispose exacerbations of asthma - Answer-M. Pneumoniae and C. Pneumoniae Is routine use of antimicrobials recommended for acute exacerbations of asthma - Answer- No, only use when likelihood of acute bacterial respiratory tract infection Name short acting beta agonist - Answer-albuterol, levalbuterol, bitolerol, pirbuterol, terbutaline What does a SABA do? - Answer-acts directly by relaxing bronchial smooth muscles. EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024 Page 2/28 What do long-term pharmacologic agents accomplish for asthma pt. - Answer-act primarily to attenuate airway inflammation. Why take long-term pharmacologic agents for asthma daily? - Answer-to achieve and maintain control of persistent asthma independent of symptoms. What does the NAEPP recommend as the cornerstone of daily treatment of persistent asthma? - Answer-daily anti-inflammatory therapy with inhaled corticosteroids Role of corticosteroids with asthma - Answer-Reduce inflammation (acute and chronic) = improved airflow, decreased airway hyper-responsiveness and fewer asthma exacerbations, and potentiate the action of beta-adrenergic agonist. 1st. line treatment agent for all pt w/persistent asthma (long term controller) - Answer- Inhaled Corticosteroids How often to most patient use inhaled corticosteroids? - Answer-Twice daily to provide adequate control. How long can it take to see maximum response of inhaled corticosterioids? - Answer- Months What can a patient do to reduce side effects of inhaled corticosteroids? - Answer-Rinse mouth after each use A patient has an exacerbation of asthma, what is the most effective treatment to achieve prompt control? - Answer-Systemic (oral) corticosteroids EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024 Page 3/28 Dose of oral corticosteroids for children during exacerbation of asthma - Answer-1-2 mg/kg/day. Can be either a single dose or divided BID. MAX 60 mg/day Dose of oral corticosteroids for adults during exacerbation of asthma - Answer-40-60 mg/day either as a single dose of divided BID Duration of treatment of oral corticosteroids for asthma exacerbation - Answer-3-10 days or until symptoms resolve (no evidence that tapering dose of PO steroids prevents relapse) When treating exacerbation of asthma, what is the preferred treatment plan? - Answer- Alternate days rather than daily treatment. What additional medications are required to be given concurrent with systemic corticosteroids to prevent corticosteroid induced bone mineral loss? - Answer-Vitamin D and Calcium Should systemic corticosteroids be rapidly discontinued? - Answer-No, to prevent adrenal insufficiency Name some mediator inhibitors to treat asthma - Answer-Cromolyn sodium and nedocromil EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024 Page 4/28 What is the mechanism of action of mediator inhibitors? - Answer-prevent asthma symptoms, improve airway function in pt w/mild persistent of exercise induce asthma When are mediator inhibitors effective? - Answer-Before allergen exposure or exercise Do not relieve asthmatic symptoms once present. Name the Long acting beta 2 agonist (LABA) for asthma - Answer-Salmeterol and Formoteol How are LABA's delivered? - Answer-dry powder What are LABA's used for - Answer-Long term prevention of asthma symptoms Nocturnal symptoms Prevention of exercise induced bronchospasm Should LABA be used as monotherapy - Answer-NO linked to fatal asthma when used alone has no anti-inflammatory effects- so use w/a cortic

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EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024




CMN 568 Unit 3 Study Guide with
Complete Solutions

What are the 3 characteristics of Asthma - Answer✔✔-Bronchoconstriction


Airway Inflammation


Reversible airflow limitation


Which inhaled anticholinergic is best used for asthma pt. w/an intolerance to beta agonist or w/

bronchospasms due to beta blocker meds? - Answer✔✔-Ipratropium Bromide


What is the primary tx for pt. w/moderate to severe asthma exacerbations who do not respond

promptly and completely to SABA? - Answer✔✔-Systemic Corticosteroids


Which bacterial infections predispose exacerbations of asthma - Answer✔✔-M. Pneumoniae

and C. Pneumoniae


Is routine use of antimicrobials recommended for acute exacerbations of asthma - Answer✔✔-

No, only use when likelihood of acute bacterial respiratory tract infection


Name short acting beta agonist - Answer✔✔-albuterol, levalbuterol, bitolerol, pirbuterol,

terbutaline


What does a SABA do? - Answer✔✔-acts directly by relaxing bronchial smooth muscles.



Page 1/28

,EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024


What do long-term pharmacologic agents accomplish for asthma pt. - Answer✔✔-act primarily

to attenuate airway inflammation.


Why take long-term pharmacologic agents for asthma daily? - Answer✔✔-to achieve and

maintain control of persistent asthma independent of symptoms.


What does the NAEPP recommend as the cornerstone of daily treatment of persistent asthma? -

Answer✔✔-daily anti-inflammatory therapy with inhaled corticosteroids


Role of corticosteroids with asthma - Answer✔✔-Reduce inflammation (acute and chronic) =

improved airflow, decreased airway hyper-responsiveness and fewer asthma exacerbations, and

potentiate the action of beta-adrenergic agonist.


1st. line treatment agent for all pt w/persistent asthma (long term controller) - Answer✔✔-

Inhaled Corticosteroids


How often to most patient use inhaled corticosteroids? - Answer✔✔-Twice daily to provide

adequate control.


How long can it take to see maximum response of inhaled corticosterioids? - Answer✔✔-

Months


What can a patient do to reduce side effects of inhaled corticosteroids? - Answer✔✔-Rinse

mouth after each use


A patient has an exacerbation of asthma, what is the most effective treatment to achieve

prompt control? - Answer✔✔-Systemic (oral) corticosteroids


Page 2/28

, EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024


Dose of oral corticosteroids for children during exacerbation of asthma - Answer✔✔-1-2

mg/kg/day.


Can be either a single dose or divided BID.


MAX 60 mg/day


Dose of oral corticosteroids for adults during exacerbation of asthma - Answer✔✔-40-60

mg/day


either as a single dose of divided BID


Duration of treatment of oral corticosteroids for asthma exacerbation - Answer✔✔-3-10 days or

until symptoms resolve


(no evidence that tapering dose of PO steroids prevents relapse)


When treating exacerbation of asthma, what is the preferred treatment plan? - Answer✔✔-

Alternate days rather than daily treatment.


What additional medications are required to be given concurrent with systemic corticosteroids

to prevent corticosteroid induced bone mineral loss? - Answer✔✔-Vitamin D and Calcium


Should systemic corticosteroids be rapidly discontinued? - Answer✔✔-No, to prevent adrenal

insufficiency


Name some mediator inhibitors to treat asthma - Answer✔✔-Cromolyn sodium and nedocromil




Page 3/28

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