PC707 Module 2 Questions And Complete
Answers
These drugs increase INR in pts taking warfarin TMP-SMX, erythromycin, fluconazole,
ketoconazole, itraconazole, metronizadole
Simvastatin or Lovestatin are HMG-CoA ihibitors metabolyzed by CYP3A4 system and should
not be taking with what drug? Biaxin (clarithromycin)
Clarithrymycin interacts with these drugs to cause severe kidney injury Calcium Channel
blockers
Fluoroquinolone/levofoxacin (Levaquin) can cause tendon rupture in what patients? Over
60, with corticosteroids, organ transplant patients.
Risk factors for development of antibiotic resistant Otitis Media Day care, less than 2
years old, abx in last 3 mths, winter/spring, local resistance pattern via antibiogram
Gram Positive Pathogens 1. Staph, 2. Strep, 3. Enterococci
, PC707 Module 2 Questions And Complete
Answers
Why does C.Diff result? C. Diff colonizing the normal gut flora resulting in toxin release
Four abx that cause C.Diff 1. Imipenem,
2. Ceftazidime,
3. clindamycin,
4. moxifloxacin
Tx of choice for mild/mod c. Dif Metronidazole 500mg PO TID x 10-14 days
Tx of choice for severe C. Diff oral Vanco
fluroquinolines are bacteriostatic or bacteriocidal bacteriocidal
black box warning: fluroquinolones Tendon Rupture (also warn for CNS pathology and
warning or lowering seizure threshold)
Answers
These drugs increase INR in pts taking warfarin TMP-SMX, erythromycin, fluconazole,
ketoconazole, itraconazole, metronizadole
Simvastatin or Lovestatin are HMG-CoA ihibitors metabolyzed by CYP3A4 system and should
not be taking with what drug? Biaxin (clarithromycin)
Clarithrymycin interacts with these drugs to cause severe kidney injury Calcium Channel
blockers
Fluoroquinolone/levofoxacin (Levaquin) can cause tendon rupture in what patients? Over
60, with corticosteroids, organ transplant patients.
Risk factors for development of antibiotic resistant Otitis Media Day care, less than 2
years old, abx in last 3 mths, winter/spring, local resistance pattern via antibiogram
Gram Positive Pathogens 1. Staph, 2. Strep, 3. Enterococci
, PC707 Module 2 Questions And Complete
Answers
Why does C.Diff result? C. Diff colonizing the normal gut flora resulting in toxin release
Four abx that cause C.Diff 1. Imipenem,
2. Ceftazidime,
3. clindamycin,
4. moxifloxacin
Tx of choice for mild/mod c. Dif Metronidazole 500mg PO TID x 10-14 days
Tx of choice for severe C. Diff oral Vanco
fluroquinolines are bacteriostatic or bacteriocidal bacteriocidal
black box warning: fluroquinolones Tendon Rupture (also warn for CNS pathology and
warning or lowering seizure threshold)
