Chemo Test 100% Correct(Graded A+)
T or F: Chemotherapy consenting is to be performed by the patient's attending physician -
ANSWERTrue
A _______ consent is required if the chemo is being used in a new way and/or a new drug is added
to the regimen - ANSWERnew
T or F: A patient can leave their shoes on when height and weight are obtained only if the patient is
suffering from peripheral neuropathy - ANSWERFalse
Who determines if actual, ideal, or adjusted body weight is to be used in chemo dosing? -
ANSWERthe physician
The Calvert formula is used to calculate the dose of what drug? - ANSWERCarboplatin
What does the AUC measure? - ANSWERArea under the curve/Drug exposure
T or F: Mrs. S is receiving Carboplatin dosed with an AUC of 6 and Mrs. H is receiving Carboplatin
with AUC of 2. The nurse knows Mrs. S may have more toxicity to the drug since her AUC is higher
than Mrs. H. - ANSWERTrue
A UPMC fellow cannot write orders independently in the first_______ - ANSWERThree months
T or F: The nurse should avoids bruised sites, the use of hand/antecubital veins, and sites distal to
veins that have experienced venipuncture in the past 24 hours when assessing where to place a new
intravenous site for chemotherapy administration - ANSWERTrue
__________ chemotherapy administered IV push should be administered at a rate of 5ml/min and
blood return should be assessed after every 2 to ______ml of drug administered - ANSWERVesicant;
3
T or F: The most accurate method to measure creatinine clearance is to collect urine for 24 hours to
measure level - ANSWERTrue
T or F: When administering an IV push medication the nurse should open the clamp of compatible
intravenous solution until increased flow is seen to dilute the agent during administration -
ANSWERTrue
During the 2 RN check, the correct patient and dose is to verified at the ________ -
ANSWERBedside/Chairside
Continuous infusion of vesicants must be through a ________ - ANSWERCentral line
Family and __________ of the patient need taught about excretion safety precautions -
ANSWERFriends
Excretion safety precautions last for _________ or _________ days - ANSWER3; 7
T or F: When evaluating a patient prior to chemotherapy, the nurse notes the patient recently had
weight loss. The nurse recalculates the dose and discovers a change in the dose greater than 10%.
, The next step for the nurse is to notify the attending physician that the patient will need re-
consented because of the dose adjustment - ANSWERFalse
Alkylating agents are cell cycle non-specific. They work on __________ and resting cells -
ANSWERDividing
Alkylating agents are effective in slow growing tumors and large tumors that have few actively
___________ cells - ANSWERDividing
List three toxicities common in all alkylating agents: - ANSWERNausea, vomiting, myelosuppression,
infertility, hypersensitivity reactions, alopecia, secondary malignancies, tumor lysis syndrome,
pregnancy category D
Which class of drugs can cross the blood brain barrier, increasing a patient's risk for CNS toxicities? -
ANSWERNitrosureas
__________ is the solvent for carmustine (BCNU) - ANSWERSterile alcohol
The ________ formula is used to calculate Carboplatin dosage - ANSWERCalvert
T or F: Temozolamide effectively crosses the blood brain barrier - ANSWERTrue
Patients may feel intoxicated during the administration of _________ - ANSWERCarmustine (BCNU)
Patients are prophylactically medicated with anticonvulsants before receiving __________ and for 24
hours after the last dose to prevent seizures - ANSWERBusulfan
T or F: Oxaliplatin should only be mixed with D5W - ANSWERTrue
Which drug should always be given with Mesna? - ANSWERIfosfamide
Pulmonary fibrosis is a late complication of patients who receive _______ - ANSWERBusulfan
The platinum alkylating agents include ________, ________, and _________ - ANSWERCisplatin;
Carboplatin; Oxaliplatin
Cisplatin is a ___________ emetogenic drug - ANSWERhighly
Pretreatment hydration is administered to prevent this toxicity of cisplatin: _________ -
ANSWERNephrotoxicity
T and F: Cisplatin should be administered before paclitaxel to prevent delayed paclitaxel excretion
and increased toxicity - ANSWERFalse
T or F: Electrolyte levels need to be closely monitored and often supplemented for cisplatin -
ANSWERTrue
The more treatments a patient receives _________ the risk for reaction with carboplatin -
ANSWERIncreases
A dose limiting adverse event associated with oxaliplatin is __________ - ANSWERNeurotoxicity
Patients should avoid cold fluids for 5 days after receiving ________ to help prevent _________ -
ANSWEROxaliplatin; Acute neurotoxicity
List 2 common side effects of antimetabolites: - ANSWERMyelosuppression, mucositis, GI symptoms,
liver dysfunction
T or F: Chemotherapy consenting is to be performed by the patient's attending physician -
ANSWERTrue
A _______ consent is required if the chemo is being used in a new way and/or a new drug is added
to the regimen - ANSWERnew
T or F: A patient can leave their shoes on when height and weight are obtained only if the patient is
suffering from peripheral neuropathy - ANSWERFalse
Who determines if actual, ideal, or adjusted body weight is to be used in chemo dosing? -
ANSWERthe physician
The Calvert formula is used to calculate the dose of what drug? - ANSWERCarboplatin
What does the AUC measure? - ANSWERArea under the curve/Drug exposure
T or F: Mrs. S is receiving Carboplatin dosed with an AUC of 6 and Mrs. H is receiving Carboplatin
with AUC of 2. The nurse knows Mrs. S may have more toxicity to the drug since her AUC is higher
than Mrs. H. - ANSWERTrue
A UPMC fellow cannot write orders independently in the first_______ - ANSWERThree months
T or F: The nurse should avoids bruised sites, the use of hand/antecubital veins, and sites distal to
veins that have experienced venipuncture in the past 24 hours when assessing where to place a new
intravenous site for chemotherapy administration - ANSWERTrue
__________ chemotherapy administered IV push should be administered at a rate of 5ml/min and
blood return should be assessed after every 2 to ______ml of drug administered - ANSWERVesicant;
3
T or F: The most accurate method to measure creatinine clearance is to collect urine for 24 hours to
measure level - ANSWERTrue
T or F: When administering an IV push medication the nurse should open the clamp of compatible
intravenous solution until increased flow is seen to dilute the agent during administration -
ANSWERTrue
During the 2 RN check, the correct patient and dose is to verified at the ________ -
ANSWERBedside/Chairside
Continuous infusion of vesicants must be through a ________ - ANSWERCentral line
Family and __________ of the patient need taught about excretion safety precautions -
ANSWERFriends
Excretion safety precautions last for _________ or _________ days - ANSWER3; 7
T or F: When evaluating a patient prior to chemotherapy, the nurse notes the patient recently had
weight loss. The nurse recalculates the dose and discovers a change in the dose greater than 10%.
, The next step for the nurse is to notify the attending physician that the patient will need re-
consented because of the dose adjustment - ANSWERFalse
Alkylating agents are cell cycle non-specific. They work on __________ and resting cells -
ANSWERDividing
Alkylating agents are effective in slow growing tumors and large tumors that have few actively
___________ cells - ANSWERDividing
List three toxicities common in all alkylating agents: - ANSWERNausea, vomiting, myelosuppression,
infertility, hypersensitivity reactions, alopecia, secondary malignancies, tumor lysis syndrome,
pregnancy category D
Which class of drugs can cross the blood brain barrier, increasing a patient's risk for CNS toxicities? -
ANSWERNitrosureas
__________ is the solvent for carmustine (BCNU) - ANSWERSterile alcohol
The ________ formula is used to calculate Carboplatin dosage - ANSWERCalvert
T or F: Temozolamide effectively crosses the blood brain barrier - ANSWERTrue
Patients may feel intoxicated during the administration of _________ - ANSWERCarmustine (BCNU)
Patients are prophylactically medicated with anticonvulsants before receiving __________ and for 24
hours after the last dose to prevent seizures - ANSWERBusulfan
T or F: Oxaliplatin should only be mixed with D5W - ANSWERTrue
Which drug should always be given with Mesna? - ANSWERIfosfamide
Pulmonary fibrosis is a late complication of patients who receive _______ - ANSWERBusulfan
The platinum alkylating agents include ________, ________, and _________ - ANSWERCisplatin;
Carboplatin; Oxaliplatin
Cisplatin is a ___________ emetogenic drug - ANSWERhighly
Pretreatment hydration is administered to prevent this toxicity of cisplatin: _________ -
ANSWERNephrotoxicity
T and F: Cisplatin should be administered before paclitaxel to prevent delayed paclitaxel excretion
and increased toxicity - ANSWERFalse
T or F: Electrolyte levels need to be closely monitored and often supplemented for cisplatin -
ANSWERTrue
The more treatments a patient receives _________ the risk for reaction with carboplatin -
ANSWERIncreases
A dose limiting adverse event associated with oxaliplatin is __________ - ANSWERNeurotoxicity
Patients should avoid cold fluids for 5 days after receiving ________ to help prevent _________ -
ANSWEROxaliplatin; Acute neurotoxicity
List 2 common side effects of antimetabolites: - ANSWERMyelosuppression, mucositis, GI symptoms,
liver dysfunction
