D027 Pathopharm Actual Exam | 114 Questions
and Answers| Latest Update | Verified Answers
What is Myasthenia Gravis? - ✔✔Autoimmune neuromuscular disease leading to fluctuating
muscle weakness and fatigue. Worsens after periods of activity. Improves after rest.
Affects breathing and movement
What causes myasthenia gravis? - ✔✔Caused by an error in the transmission of nerve
impulses to muscle and neuromuscular junction where nerve cells connect to the muscles they
control
Myasthenia Gravis s/s - ✔✔Weakness of eye/eyelid movement, facial expressions, chewing,
talking, swallowing, ptosis, SOB, weakness in arms, hands, fingers, legs, neck.
How is myasthenia gravis diagnosed? - ✔✔Edrophonium/Tensilon test- briefly relieves
weakness by blocking the breakdown of acetylcholinesterase and increases levels at NMJ.
Acetylcholinesterase and anti-musk antibody test
CT/MRI to identify thymoma
Pulmonary function test
How do you treat Myasthenia Gravis - ✔✔1. Monoclonal antibody
2. Anti-cholinesterase meds (neostigmine, pyridostigmine)
3. Prednisone
,myasthenia gravis non-pharm treatment - ✔✔1. Thymectomy (thymus gland causes disease)
2. Plasmapheresis
3. IV immunoglobulin
4. Hydrotherapy
What meds can be given to treat neuropathic pain? - ✔✔Gabapentin (Neurontin)
Pregabalin (Lyrica)
Antidepressants (amytriptyline)
Pain meds (oxycodone)
Anti-seizure meds
Important to treat underlying condition
What are the non-pharmacological treatments for neuropathic pain? - ✔✔Pain relieving
creams
Quit smoking
Warm baths
Exercise
Essential oils
Acupuncture
Meditation
How do you treat a pleural effusion? - ✔✔Depends on the condition's etiology.
, 1. Diuretics = CHF and pulmonary edema
2. Anbx = parapneumonic effusion/empyema
3. Anticoagulantion = PE
What is non-pharmaceutical
treatment for a pleural effusion? - ✔✔Thoracentesis
Chest tube
Pleural drain for reoccurring effusion
O2
Avoid exacerbating activities
How do you diagnose small cell lung carcinoma? - ✔✔Epidermal growth factor receptor
(EGFR)
CXR
What is a normal TSH level? - ✔✔0.5-5.0 mU/L
What is a normal T3 and T4 level? - ✔✔T3 = 80-220 ug/dL
T4 = 5-12 ug/dL
What is hyperthyroidism (Graves disease)? - ✔✔Over production of thyroid hormones.
and Answers| Latest Update | Verified Answers
What is Myasthenia Gravis? - ✔✔Autoimmune neuromuscular disease leading to fluctuating
muscle weakness and fatigue. Worsens after periods of activity. Improves after rest.
Affects breathing and movement
What causes myasthenia gravis? - ✔✔Caused by an error in the transmission of nerve
impulses to muscle and neuromuscular junction where nerve cells connect to the muscles they
control
Myasthenia Gravis s/s - ✔✔Weakness of eye/eyelid movement, facial expressions, chewing,
talking, swallowing, ptosis, SOB, weakness in arms, hands, fingers, legs, neck.
How is myasthenia gravis diagnosed? - ✔✔Edrophonium/Tensilon test- briefly relieves
weakness by blocking the breakdown of acetylcholinesterase and increases levels at NMJ.
Acetylcholinesterase and anti-musk antibody test
CT/MRI to identify thymoma
Pulmonary function test
How do you treat Myasthenia Gravis - ✔✔1. Monoclonal antibody
2. Anti-cholinesterase meds (neostigmine, pyridostigmine)
3. Prednisone
,myasthenia gravis non-pharm treatment - ✔✔1. Thymectomy (thymus gland causes disease)
2. Plasmapheresis
3. IV immunoglobulin
4. Hydrotherapy
What meds can be given to treat neuropathic pain? - ✔✔Gabapentin (Neurontin)
Pregabalin (Lyrica)
Antidepressants (amytriptyline)
Pain meds (oxycodone)
Anti-seizure meds
Important to treat underlying condition
What are the non-pharmacological treatments for neuropathic pain? - ✔✔Pain relieving
creams
Quit smoking
Warm baths
Exercise
Essential oils
Acupuncture
Meditation
How do you treat a pleural effusion? - ✔✔Depends on the condition's etiology.
, 1. Diuretics = CHF and pulmonary edema
2. Anbx = parapneumonic effusion/empyema
3. Anticoagulantion = PE
What is non-pharmaceutical
treatment for a pleural effusion? - ✔✔Thoracentesis
Chest tube
Pleural drain for reoccurring effusion
O2
Avoid exacerbating activities
How do you diagnose small cell lung carcinoma? - ✔✔Epidermal growth factor receptor
(EGFR)
CXR
What is a normal TSH level? - ✔✔0.5-5.0 mU/L
What is a normal T3 and T4 level? - ✔✔T3 = 80-220 ug/dL
T4 = 5-12 ug/dL
What is hyperthyroidism (Graves disease)? - ✔✔Over production of thyroid hormones.
