Oxford Cambridge and RSA
Friday 10 May 2024 – Morning
GCSE (9–1) Combined Science A
(Gateway Science)
J250/07 Biology (Higher Tier)
Time allowed: 1 hour 10 minutes
You must have:
• a ruler (cm/mm)
H
You can use:
• a scientific or graphical calculator
• an HB pencil
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 60.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 24 pages.
ADVICE
• Read each question carefully before you start your answer.
OCR is an exempt Charity
Turn over
, 2
Section A
You should spend a maximum of 20 minutes on this section.
Write your answer to each question in the box provided.
1 The table shows some information about insulin in the body.
Which row shows the correct information about insulin?
Organ that produces insulin Type of signal Target organ
A liver chemical pancreas
B liver electrical pancreas
C pancreas chemical liver
D pancreas electrical liver
Your answer [1]
2 The length of a bacteria cell is 5.3 µm.
What is the length of this cell in mm?
(1 mm = 1000 µm)
A 5.3 × 10–6
B 5.3 × 10–3
C 5.3 × 103
D 5.3 × 106
Your answer [1]
© OCR 2024
, 3
3 What are two characteristics of a cell membrane?
A Non-selective barrier and contains plasmids
B Non-selective barrier and contains receptors
C Selective barrier and contains plasmids
D Selective barrier and contains receptors
Your answer [1]
4 The diagrams show stages in the hypothesis used to explain the mechanism of enzyme action.
Which term describes the molecule labelled M?
M
A Active site
B Enzyme
C Lock and key
D Substrate
Your answer [1]
5 What is a difference between embryonic stem cells and adult stem cells?
A Adult stem cells are less likely to be rejected when used in transplants.
B Only embryonic stem cells can differentiate.
C Only embryonic stem cells produce a full range of different cell types.
D There are more ethical issues in the use of adult stem cells.
Your answer [1]
© OCR 2024 Turn over
, 4
6 The resolution of a microscope is limited to half the wavelength of light used to see the image.
Our eyes only detect light with a wavelength greater than 400 nm.
What is the approximate resolution of a light microscope?
(1000 nm = 1 µm)
A <0.2 µm
B ~0.2 µm
C ~0.4 µm
D >0.4 µm
Your answer [1]
7 The photograph shows two different blood vessels.
Blood vessel T Blood vessel S
Which statement about these blood vessels is correct?
A Blood flows through blood vessel T at a slower rate.
B Blood vessel S has a thinner muscular wall.
C Blood vessel T has a larger lumen diameter.
D Both blood vessels transport blood to the heart.
Your answer [1]
© OCR 2024
Friday 10 May 2024 – Morning
GCSE (9–1) Combined Science A
(Gateway Science)
J250/07 Biology (Higher Tier)
Time allowed: 1 hour 10 minutes
You must have:
• a ruler (cm/mm)
H
You can use:
• a scientific or graphical calculator
• an HB pencil
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 60.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 24 pages.
ADVICE
• Read each question carefully before you start your answer.
OCR is an exempt Charity
Turn over
, 2
Section A
You should spend a maximum of 20 minutes on this section.
Write your answer to each question in the box provided.
1 The table shows some information about insulin in the body.
Which row shows the correct information about insulin?
Organ that produces insulin Type of signal Target organ
A liver chemical pancreas
B liver electrical pancreas
C pancreas chemical liver
D pancreas electrical liver
Your answer [1]
2 The length of a bacteria cell is 5.3 µm.
What is the length of this cell in mm?
(1 mm = 1000 µm)
A 5.3 × 10–6
B 5.3 × 10–3
C 5.3 × 103
D 5.3 × 106
Your answer [1]
© OCR 2024
, 3
3 What are two characteristics of a cell membrane?
A Non-selective barrier and contains plasmids
B Non-selective barrier and contains receptors
C Selective barrier and contains plasmids
D Selective barrier and contains receptors
Your answer [1]
4 The diagrams show stages in the hypothesis used to explain the mechanism of enzyme action.
Which term describes the molecule labelled M?
M
A Active site
B Enzyme
C Lock and key
D Substrate
Your answer [1]
5 What is a difference between embryonic stem cells and adult stem cells?
A Adult stem cells are less likely to be rejected when used in transplants.
B Only embryonic stem cells can differentiate.
C Only embryonic stem cells produce a full range of different cell types.
D There are more ethical issues in the use of adult stem cells.
Your answer [1]
© OCR 2024 Turn over
, 4
6 The resolution of a microscope is limited to half the wavelength of light used to see the image.
Our eyes only detect light with a wavelength greater than 400 nm.
What is the approximate resolution of a light microscope?
(1000 nm = 1 µm)
A <0.2 µm
B ~0.2 µm
C ~0.4 µm
D >0.4 µm
Your answer [1]
7 The photograph shows two different blood vessels.
Blood vessel T Blood vessel S
Which statement about these blood vessels is correct?
A Blood flows through blood vessel T at a slower rate.
B Blood vessel S has a thinner muscular wall.
C Blood vessel T has a larger lumen diameter.
D Both blood vessels transport blood to the heart.
Your answer [1]
© OCR 2024
