Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
h h h h h h h h h
By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton
h h h h h h h h h
Complete
h
,Chapter 01: Drug Definitions, Standards, and Information Sources
h h h h h h h
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
h h h h h h h h
MULTIPLE CHOICE h
1. Which name identifies a drug listed by the US Food and
h h h h h h h h h h
h Drug Administration (FDA)?
h h
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C h
The official name is the name under which a drug is listed
h h h h h h h h h h h
by the FDA. The brand name, or trademark, is the name
h h h h h h h h h h h
given to a drug by its manufacturer. The nonproprietary, or
h h h h h h h h h h
generic, name is provided by the United States Adopted
h h h h h h h h h
Names Council.
h h
DIF: Cognitive Level: Knowledge REF: p. 9 h h h h
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care
h h h h h h h h
Environment TOP: Nursing Process Step: Assessment
h h CON: h h h h
Patient Education
h h
2. Which source contains information specific to nutritional supplements?
h h h h h h h
a. USP Dictionary of USAN & International Drug Names
h h h h h h h
b. Natural Medicines Comprehensive Database h h h
c. United States Pharmacopoeia/National Formulary (USP NF)
h h h h h
d. Drug Interaction Facts h h
ANS: C h
United States Pharmacopoeia/National Formulary contains information specific to nutritional
h h h h h h h h
supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
h h h h h h h h h h h h h h
names, pronunciation guide, and possible future FDA approved drugs; it does not include
h h h h h h h h h h h h h
nutritional supplements. Natural Medicines Comprehensive Database contains
h h h h h h h
evidence-based information on herbal medicines and herbal combination products; it does not
h h h h h h h h h h h
include information specific to nutritional supplements. Drug Interaction Facts contains
h h h h h h h h h h
comprehensive information on drug interaction facts; it does not include nutritional
h h h h h h h h h h h
supplements.
h
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3 h h h h h
NAT: NCLEX Client Needs Category: Physiological Integrity
h h h h h h h
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
h h h h h h h h
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
h h h h h h h h h h h h h
a. Drug Facts and Comparisons h h h
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
h h h h h h h h h 3
b. Drug Interaction Facts h h
c. Handbook on Injectable Drugs h h h
d. Martindale—The Complete Drug Reference h h h
ANS: A h
Drug Facts and Comparisons contains drug monographs that describe all drugs in a
h h h h h h h h h h h h
therapeutic class. Monographs are formatted as tables to allow comparison of similar
h h h h h h h h h h h h
products, brand names, manufacturers, cost indices, and available dosage forms
h h h h h h h h h h
Online version is available.
h h h h
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 h h h h h h
OBJ: 3 h NAT: NCLEX Client Needs Category: Physiological Integrity
h h h h h h h
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
h h h h h hh h h h h
4. Which drug reference contains monographs about virtually every single-entity drug available
h h h h h h h h h h
in the United States and describes therapeutic uses of drugs, including approved and
h h h h h h h h h h h h h
unapproved uses?
h h
a. Martindale: The Complete Drug Reference h h h h
b. AHFS Drug Information h h
c. Drug Reference h
d. Drug Facts and Comparisons h h h
ANS: B h
AHFS Drug Information contains monographs about virtually every single-entity drug
h h h h h h h h h
available in the United States and describes therapeutic uses of drugs, including approved and
h h h h h h h h h h h h h h
unapproved uses.
h h
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 h h h h h h
OBJ: 3 h NAT: NCLEX Client Needs Category: Physiological Integrity
h h h h h h h
TOP: Nursing Process Step: Planning
h CON: Safety | Patient Education | Clinical Judgment
h h h h hh h h h h
5. Which online drug reference makes available to healthcare providers and the public a
h h h h h h h h h h h h
standard, comprehensive, up-to-date look up and downloadable resource about medicines?
h h h h h h h h h h
a. American Drug Index h h
b. American Hospital Formulary h h
c. DailyMed
d. Drug Reference h
ANS: C h
DailyMed makes available to healthcare providers and the public a standard, comprehensive,
h h h h h h h h h h h
up-to-date look up and downloadable resource about medicines. The American Drug Index is
h h h h h h h h h h h h h
not appropriate for patient use. The American Hospital Formulary is not appropriate for
h h h h h h h h h h h h h
patient use. The drug reference is not appropriate for patient use.
h h h h h h h h h h h
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 h h h h h h h OBJ: 3 h
NAT: NCLEX Client Needs Category: Physiological Integrity
h h h h h h h
TOP: Nursing Process Step: Implementation
h h h h
CON: Safety | Patient Education | Clinical Judgment
h h h h h h h
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
h h h h h h h h h h h h h h
a. Federal Food, Drug, and Cosmetic Act (1938) h h h h h h
b. Durham Humphrey Amendment (1952) h h h
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
h h h h h h h h h 4
c. Controlled Substances Act (1970) h h h
d. Kefauver Harris Drug Amendment (1962) h h h h
ANS: A h
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
h h h h h h h h h h h h h h
safety of all drugs before marketing. Later amendments and acts helped tighten FDA control
h h h h h h h h h h h h h h
and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that
h h h h h h h h h h h h h h
cannot be used safely without medical supervision and restricts their sale to prescription by a
h h h h h h h h h h h h h h h
licensed practitioner. The Controlled Substances Act addresses only controlled substances and
h h h h h h h h h h h
their categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater
h h h h h h h h h h h h
drug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their
h h h h h h h h h h h h h h h
products before marketing them.
h h h h
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3
h h h h h h
OBJ: h 5 NAT: NCLEX Client Needs Category: Physiological Integrity h h h h h h
TOP:
h hNursing Process Step: Assessment h h h
CON: Safety | Patient Education | Evidence | Health Care Law
h h h h h h h h h h
7. Which classification does meperidine (Demerol) fall under?
h h h h h h
a. I
b. II
c. III
d. IV
ANS: B h
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
h h h h h h h h h h h h h h h h h
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
h h h h h h h h h h h h h
and no recognized medical use. Schedule III drugs have some potential for abuse. Use may
h h h h h h h h h h h h h h h
lead to low to moderate physical dependence or high psychological dependence. Schedule IV
h h h h h h h h h h h h h
drugs have low potential for abuse. Use may lead to limited physical or psychological
h h h h h h h h h h h h h h
dependence.
h
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2 h h h h h
NAT: NCLEX Client Needs Category: Safe, Effective Care
h h h h h h h h
Environment
h
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
h h h h h h h h h h
8. Which action would the FDA take to expedite drug development and approval for an outbreak
h h h h h h h h h h h h h h
h of smallpox?
h
a. List smallpox as a health orphan disease.
h h h h h h
b. Omit the preclinical research phase. h h h h
c. Extend the clinical research phase. h h h h
d. Fast track the investigational drug.
h h h h
ANS: D h
Once the Investigational New Drug Application has been approved, the drug can receive
h h h h h h h h h h h h
highest priority within the agency, which is called fast tracking. A smallpox outbreak would
h h h h h h h h h h h h h h
become a priority concern in the world. Orphan diseases are not researched in a priority
h h h h h h h h h h h h h h h
manner. Preclinical research is not omitted. Extending any phase of the research would mean
h h h h h h h h h h h h h h
a longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical and
h h h h h h h h h h h h h h h h h h
clinical research phase have been completed in a safe manner.
h h h h h h h h h h
DIF: Cognitive Level: Knowledge h h REF: h h p. 7 h OBJ: 5 h
h h h h h h h h h
By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton
h h h h h h h h h
Complete
h
,Chapter 01: Drug Definitions, Standards, and Information Sources
h h h h h h h
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
h h h h h h h h
MULTIPLE CHOICE h
1. Which name identifies a drug listed by the US Food and
h h h h h h h h h h
h Drug Administration (FDA)?
h h
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C h
The official name is the name under which a drug is listed
h h h h h h h h h h h
by the FDA. The brand name, or trademark, is the name
h h h h h h h h h h h
given to a drug by its manufacturer. The nonproprietary, or
h h h h h h h h h h
generic, name is provided by the United States Adopted
h h h h h h h h h
Names Council.
h h
DIF: Cognitive Level: Knowledge REF: p. 9 h h h h
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care
h h h h h h h h
Environment TOP: Nursing Process Step: Assessment
h h CON: h h h h
Patient Education
h h
2. Which source contains information specific to nutritional supplements?
h h h h h h h
a. USP Dictionary of USAN & International Drug Names
h h h h h h h
b. Natural Medicines Comprehensive Database h h h
c. United States Pharmacopoeia/National Formulary (USP NF)
h h h h h
d. Drug Interaction Facts h h
ANS: C h
United States Pharmacopoeia/National Formulary contains information specific to nutritional
h h h h h h h h
supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
h h h h h h h h h h h h h h
names, pronunciation guide, and possible future FDA approved drugs; it does not include
h h h h h h h h h h h h h
nutritional supplements. Natural Medicines Comprehensive Database contains
h h h h h h h
evidence-based information on herbal medicines and herbal combination products; it does not
h h h h h h h h h h h
include information specific to nutritional supplements. Drug Interaction Facts contains
h h h h h h h h h h
comprehensive information on drug interaction facts; it does not include nutritional
h h h h h h h h h h h
supplements.
h
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3 h h h h h
NAT: NCLEX Client Needs Category: Physiological Integrity
h h h h h h h
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
h h h h h h h h
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
h h h h h h h h h h h h h
a. Drug Facts and Comparisons h h h
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
h h h h h h h h h 3
b. Drug Interaction Facts h h
c. Handbook on Injectable Drugs h h h
d. Martindale—The Complete Drug Reference h h h
ANS: A h
Drug Facts and Comparisons contains drug monographs that describe all drugs in a
h h h h h h h h h h h h
therapeutic class. Monographs are formatted as tables to allow comparison of similar
h h h h h h h h h h h h
products, brand names, manufacturers, cost indices, and available dosage forms
h h h h h h h h h h
Online version is available.
h h h h
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 h h h h h h
OBJ: 3 h NAT: NCLEX Client Needs Category: Physiological Integrity
h h h h h h h
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
h h h h h hh h h h h
4. Which drug reference contains monographs about virtually every single-entity drug available
h h h h h h h h h h
in the United States and describes therapeutic uses of drugs, including approved and
h h h h h h h h h h h h h
unapproved uses?
h h
a. Martindale: The Complete Drug Reference h h h h
b. AHFS Drug Information h h
c. Drug Reference h
d. Drug Facts and Comparisons h h h
ANS: B h
AHFS Drug Information contains monographs about virtually every single-entity drug
h h h h h h h h h
available in the United States and describes therapeutic uses of drugs, including approved and
h h h h h h h h h h h h h h
unapproved uses.
h h
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 h h h h h h
OBJ: 3 h NAT: NCLEX Client Needs Category: Physiological Integrity
h h h h h h h
TOP: Nursing Process Step: Planning
h CON: Safety | Patient Education | Clinical Judgment
h h h h hh h h h h
5. Which online drug reference makes available to healthcare providers and the public a
h h h h h h h h h h h h
standard, comprehensive, up-to-date look up and downloadable resource about medicines?
h h h h h h h h h h
a. American Drug Index h h
b. American Hospital Formulary h h
c. DailyMed
d. Drug Reference h
ANS: C h
DailyMed makes available to healthcare providers and the public a standard, comprehensive,
h h h h h h h h h h h
up-to-date look up and downloadable resource about medicines. The American Drug Index is
h h h h h h h h h h h h h
not appropriate for patient use. The American Hospital Formulary is not appropriate for
h h h h h h h h h h h h h
patient use. The drug reference is not appropriate for patient use.
h h h h h h h h h h h
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 h h h h h h h OBJ: 3 h
NAT: NCLEX Client Needs Category: Physiological Integrity
h h h h h h h
TOP: Nursing Process Step: Implementation
h h h h
CON: Safety | Patient Education | Clinical Judgment
h h h h h h h
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
h h h h h h h h h h h h h h
a. Federal Food, Drug, and Cosmetic Act (1938) h h h h h h
b. Durham Humphrey Amendment (1952) h h h
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
h h h h h h h h h 4
c. Controlled Substances Act (1970) h h h
d. Kefauver Harris Drug Amendment (1962) h h h h
ANS: A h
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
h h h h h h h h h h h h h h
safety of all drugs before marketing. Later amendments and acts helped tighten FDA control
h h h h h h h h h h h h h h
and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that
h h h h h h h h h h h h h h
cannot be used safely without medical supervision and restricts their sale to prescription by a
h h h h h h h h h h h h h h h
licensed practitioner. The Controlled Substances Act addresses only controlled substances and
h h h h h h h h h h h
their categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater
h h h h h h h h h h h h
drug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their
h h h h h h h h h h h h h h h
products before marketing them.
h h h h
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3
h h h h h h
OBJ: h 5 NAT: NCLEX Client Needs Category: Physiological Integrity h h h h h h
TOP:
h hNursing Process Step: Assessment h h h
CON: Safety | Patient Education | Evidence | Health Care Law
h h h h h h h h h h
7. Which classification does meperidine (Demerol) fall under?
h h h h h h
a. I
b. II
c. III
d. IV
ANS: B h
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
h h h h h h h h h h h h h h h h h
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
h h h h h h h h h h h h h
and no recognized medical use. Schedule III drugs have some potential for abuse. Use may
h h h h h h h h h h h h h h h
lead to low to moderate physical dependence or high psychological dependence. Schedule IV
h h h h h h h h h h h h h
drugs have low potential for abuse. Use may lead to limited physical or psychological
h h h h h h h h h h h h h h
dependence.
h
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2 h h h h h
NAT: NCLEX Client Needs Category: Safe, Effective Care
h h h h h h h h
Environment
h
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
h h h h h h h h h h
8. Which action would the FDA take to expedite drug development and approval for an outbreak
h h h h h h h h h h h h h h
h of smallpox?
h
a. List smallpox as a health orphan disease.
h h h h h h
b. Omit the preclinical research phase. h h h h
c. Extend the clinical research phase. h h h h
d. Fast track the investigational drug.
h h h h
ANS: D h
Once the Investigational New Drug Application has been approved, the drug can receive
h h h h h h h h h h h h
highest priority within the agency, which is called fast tracking. A smallpox outbreak would
h h h h h h h h h h h h h h
become a priority concern in the world. Orphan diseases are not researched in a priority
h h h h h h h h h h h h h h h
manner. Preclinical research is not omitted. Extending any phase of the research would mean
h h h h h h h h h h h h h h
a longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical and
h h h h h h h h h h h h h h h h h h
clinical research phase have been completed in a safe manner.
h h h h h h h h h h
DIF: Cognitive Level: Knowledge h h REF: h h p. 7 h OBJ: 5 h
