ATI Pharmacology RN
Digoxin (lanoxin) SE - ANS blurred/double vision
Dry Cough
Facial Edema
Guaifenesin SE - ANS A/E: Diarrhea, can cause drowsiness
TELL: Increase fluids by at least 2L/day
store at room temp not fridge
Doxepin (Sinequan) [anticholinergic] SE - ANS urinary retension, constipation, drying of
nasal/oral secretions, ↑HR
Albuterol (Proventil) [sympathomimetic/ adrenergic beta-2 agonist] Contraindicated - ANS with
MAOIs (can↑ action of albuterol and → HTN crisis); β-blockers can inhibit the therapeutic effects
Use: invert canister, shake before use, rinse mouth after use, w/new inhaler perform test spray
Levothyroxine (T4) Indication - ANS hypothyroidism RT dysfxn of hypothalamus, pituitary, or
thyroid gland
Monitor for: Chest pain, tremors, nervousness, insomnia
Cephalosporins (Keflex) - ANS allergy to cephalosporins is considered a precaution for taking
penicillins
Phenobarbital [Barbiturates]; interventions for anticonvulsant therapy - ANS assess for resp.
depression, excess sedation from toxic effects, IV at < 50mg/min, avoid extravasation
(alkaline→skin damage)
Sumatriptan (Imitrex) use - ANS when migraine symptoms appear and again in 1 hr if
symptoms persist
Report: Chest pressure/ Heavy arms (vasospasm= angina) monitor
Sedation and Drowsiness can occur
Baclofen (Lioresal) Therapeutic action - ANS ↓ frequency & severity of muscle spasms
A/E: Monitor for seizure risk patients: increased risk for seizures
A/E: Memory impairment
A/E: decreased cognitive function
Erythromycin (Erythrocin) [macrolide] SE - ANS liver toxicity
What do need to avoid when taking Spironolactone (Aldactone) [K sparing diuretic] - ANS foods
w/ ↑ K such as salt substitutes
, Chloroquine phosphate (Aralen): Indication - ANS malaria prevention; Use: take weekly starting
1 week before departure and continued for 4 weeks after return.
Heparin (anticoagulant) Use - ANS w/alteplase for acute MI
Warfarin (Coumadin) Use - ANS long-term prophylaxis of thrombosis [antidote—Vit K]
Clopidogrel (Plavix) Use - ANS reduce long-term risk of clotting w/ atherosclerosis and recent
MI of CVA
Alteplase (Activase) [antithrombolytic] Use - ANS Acute MI/CVA (has short half-life)
Methylphenidate (Concerta) Use - ANS marcolepsy Precaution: avoid caffeine use
Testosterone IM use - ANS If use to correct delayed puberty→assess bone maturation with
bi-annual x-rays of hand and wrist; monitor liver function (can ↑ hypoglycemia, potentiate sleep
apnea, exacerbate heart failure due to fluid retention.
Diphenoxylate & Atropine (Lomotil) Caution - ANS With Renal impairment ↓ elimination of
atropine → ↑ anticholinergic effects of atropine like confusion
Loperamide (Imodium) use - ANS anti-diarrheal (poorly absorbed from GI tract; difficulty
crossing the blood-brain barrier)
Methylcellulose (Citrucel) use - ANS bulk-forming agent with minimal Side Effects (SE)
Psyllium (Metamucil) use - ANS bulk-forming agent with minimal Side Effects (SE)
Acetazolamide (Diamox) [diuretic] indication - ANS edema, epilepsy, acute mountain sickness,
glaucoma (↓ intraocular pressure by ↓ amount of aqueous humor in the eye)
Contra: allergy to sulfonamides
Report: Tingling of the fingers (Paresthesia)
Diarrhea
Weight loss (decrease appetite )
Polyuria
Metoprolol (Lopressor) [β-blocker] use and side effects - ANS Hold dose for dyspnea (sign of
exacerbation of CHF) Propanolol (Inderal) Use. Dysrhythmia, HTN, angina; SE:
bronchoconstriction/bronchospasm; can block glyconeogenesis
Norgestrel (Ovrette) use and contraindication - ANS contraception; SE: excess progestin
→weight gain from ↑ appetite; deficiency of progestin: late breakthrough bleeding, amenorrhea;
excess estrogen → edema Medroxyprogesterone (Provera); Contra: smoking/tobacco products;
Digoxin (lanoxin) SE - ANS blurred/double vision
Dry Cough
Facial Edema
Guaifenesin SE - ANS A/E: Diarrhea, can cause drowsiness
TELL: Increase fluids by at least 2L/day
store at room temp not fridge
Doxepin (Sinequan) [anticholinergic] SE - ANS urinary retension, constipation, drying of
nasal/oral secretions, ↑HR
Albuterol (Proventil) [sympathomimetic/ adrenergic beta-2 agonist] Contraindicated - ANS with
MAOIs (can↑ action of albuterol and → HTN crisis); β-blockers can inhibit the therapeutic effects
Use: invert canister, shake before use, rinse mouth after use, w/new inhaler perform test spray
Levothyroxine (T4) Indication - ANS hypothyroidism RT dysfxn of hypothalamus, pituitary, or
thyroid gland
Monitor for: Chest pain, tremors, nervousness, insomnia
Cephalosporins (Keflex) - ANS allergy to cephalosporins is considered a precaution for taking
penicillins
Phenobarbital [Barbiturates]; interventions for anticonvulsant therapy - ANS assess for resp.
depression, excess sedation from toxic effects, IV at < 50mg/min, avoid extravasation
(alkaline→skin damage)
Sumatriptan (Imitrex) use - ANS when migraine symptoms appear and again in 1 hr if
symptoms persist
Report: Chest pressure/ Heavy arms (vasospasm= angina) monitor
Sedation and Drowsiness can occur
Baclofen (Lioresal) Therapeutic action - ANS ↓ frequency & severity of muscle spasms
A/E: Monitor for seizure risk patients: increased risk for seizures
A/E: Memory impairment
A/E: decreased cognitive function
Erythromycin (Erythrocin) [macrolide] SE - ANS liver toxicity
What do need to avoid when taking Spironolactone (Aldactone) [K sparing diuretic] - ANS foods
w/ ↑ K such as salt substitutes
, Chloroquine phosphate (Aralen): Indication - ANS malaria prevention; Use: take weekly starting
1 week before departure and continued for 4 weeks after return.
Heparin (anticoagulant) Use - ANS w/alteplase for acute MI
Warfarin (Coumadin) Use - ANS long-term prophylaxis of thrombosis [antidote—Vit K]
Clopidogrel (Plavix) Use - ANS reduce long-term risk of clotting w/ atherosclerosis and recent
MI of CVA
Alteplase (Activase) [antithrombolytic] Use - ANS Acute MI/CVA (has short half-life)
Methylphenidate (Concerta) Use - ANS marcolepsy Precaution: avoid caffeine use
Testosterone IM use - ANS If use to correct delayed puberty→assess bone maturation with
bi-annual x-rays of hand and wrist; monitor liver function (can ↑ hypoglycemia, potentiate sleep
apnea, exacerbate heart failure due to fluid retention.
Diphenoxylate & Atropine (Lomotil) Caution - ANS With Renal impairment ↓ elimination of
atropine → ↑ anticholinergic effects of atropine like confusion
Loperamide (Imodium) use - ANS anti-diarrheal (poorly absorbed from GI tract; difficulty
crossing the blood-brain barrier)
Methylcellulose (Citrucel) use - ANS bulk-forming agent with minimal Side Effects (SE)
Psyllium (Metamucil) use - ANS bulk-forming agent with minimal Side Effects (SE)
Acetazolamide (Diamox) [diuretic] indication - ANS edema, epilepsy, acute mountain sickness,
glaucoma (↓ intraocular pressure by ↓ amount of aqueous humor in the eye)
Contra: allergy to sulfonamides
Report: Tingling of the fingers (Paresthesia)
Diarrhea
Weight loss (decrease appetite )
Polyuria
Metoprolol (Lopressor) [β-blocker] use and side effects - ANS Hold dose for dyspnea (sign of
exacerbation of CHF) Propanolol (Inderal) Use. Dysrhythmia, HTN, angina; SE:
bronchoconstriction/bronchospasm; can block glyconeogenesis
Norgestrel (Ovrette) use and contraindication - ANS contraception; SE: excess progestin
→weight gain from ↑ appetite; deficiency of progestin: late breakthrough bleeding, amenorrhea;
excess estrogen → edema Medroxyprogesterone (Provera); Contra: smoking/tobacco products;
