NU 545 Advance Pathophysiology Unit 6
Exam 257 approved and verified Answers.
NU 545 Advance Pathophysiology Unit 6
Exam 257 approved and verified Answers.
Glandular neoplasms and Ectopic Hormone Release are associated with - answer-
Hypersecretion
Receptor Disorders, Inadequate hormone synthesis, and degraded or inactivated
hormones are associated with - answer- Hyposecretion
What is the major link between the nervous system and endocrine system - answer-
The hypothalamus
Antidiuretic Hormone controls - answer- Cells at the distal collecting tubule of the kidney
to prevent the secretion of water
Specifically ADH has what effect - answer- It increases aquaporin production by DCT
cells in the distal collecting tubules
ADH decreases - answer- The plamsa osmolality
Syndrome of Innapropriate ADH is - answer- an Inappropriate secretion of ADH in the
absence of normal physiologic stimuli ie thirst
Syndrome of Inappropriate ADH results in - answer- Water retention
Inability of the body to excrete dilute urine
Hypervolemia
Hyponatremia
In SIADH an elevation in ADH level despite low serum sodium level continues to
decrease the plasma concentration resulting in - answer- a shift of more water to the
intracellular space
Cellular edema leads to headache and other neurological signs and symptoms
What is the opposite of SIADH - answer- Diabetes Insipidous
Diabetes Insipidus is caused by - answer- the insufficient release of ADH
Causes patient to excret to much urine
>2.5 L/day
50% 4-8L/Day
25% 8-12L/Day
What are the two types of Diabetes Insipidus - answer- Neurogenic which is more
common
Nephrogenic
,NU 545 Advance Pathophysiology Unit 6
Exam 257 approved and verified Answers.
Neurogenic Diabetes Insipidus can be explained as - answer- Lesion in hypothalamus,
pituitary, or infundibulum resutling in decreased ADH secretion
Nephrogenic Diabetes Insipidus can be explained as - answer- Insesitivity of Renal
tubules to ADH
Hypopituitarism is - answer- An anterior pituitary disorder
Infarction of the gland
Remaoval/destruction of the pituitary
Space occupying pituitary adenomas
Aneurysms that cause compression
Absence of all hormones in the anterior pituitary is called - answer- Panhypopituitarism
Treatment may consist of replacing HGH, ACTH, TSH, and sex hormones
Pituitary dwarfism is caused by - answer- Insufficient HGH release during an individuals
growth phase
In pituitary dwarfism, the patient has - answer- normal face and intelligence, with normal
body proportions
Hyperpituitarism is most common cause of - answer- Pituitary Adenoma
Giantism - answer- Occurs as a result of excess HGH during an individuals growth
phase
Acromegaly - answer- Occurs as a result of excess HGH during adulthood
Acromegaly is marked by the - answer- enlargement and elongation of the bones of the
face, jaw, cheeks, and hands
What is unnafected in acromegaly - answer- The long bones of the extremities are
unaffected because the growth plates are closed
In Acromegaly, with bony and soft tissue overgrowth what can be entrapped - answer-
Nerves
The patient may demonstrate muscle weakness, foot drop, and sensory changes.
Increased size and function of sebaceous and sweat glands increases body odor
Explain the sacs of the thyroid gland - answer- Sacs in the thyroid gland make up most
of the thyroid gland. They are called Thyroid follicles and secret two hormones
Thyroxine T4 and Triodothyronine T3
, NU 545 Advance Pathophysiology Unit 6
Exam 257 approved and verified Answers.
thyroid hormones do what? - answer- REgulate oxygen use
Increase the basal metabolic rate
Increase cellular carbohydrate and protein catabolism
Increase reactivity of the nervous system
Along with HGH, controls tissue growth and development
Hypothyroidism has this effect on cardiac function - answer- Low output Bradycardia
Hyperthryoidism has this effect on cardiac function - answer- increased output
tachycardia
Hypothyroidism has this effect on respiratory function - answer- Hypoventilation
Hyperthyroidism has this effect on respiratory function - answer- Dyspnea
Appearance of Hypothyroidism - answer- Myxedematous
Appearance of Hyperthyroidism - answer- Enlarged thyroid and decreased blinking
What is a goiter - answer- An enlarged thyroid gland due to increase demand for thyroid
hormones
What causes a goiter - answer- Iodine deficiency
Viral or genetic disease
Puberty
PRegnancy
What increases in number due to TSH stimulation and causes a goiter - answer-
Follicles
When can a goiter manifest - answer- During hypothyroidism
Hyperthyroidism
Euthyroidism
GRaves disorder is what? - answer- A automimmune disorder where antibodies are
made against TSH receptors of thyroid cells
In graves disease, the antibodies act as - answer- TSH agonists turning on the
production of thyroxin
Excess thyroxin secretion leads to - answer- Thyrotoxicosis aka symptomatic
hyperthyroidism
Exam 257 approved and verified Answers.
NU 545 Advance Pathophysiology Unit 6
Exam 257 approved and verified Answers.
Glandular neoplasms and Ectopic Hormone Release are associated with - answer-
Hypersecretion
Receptor Disorders, Inadequate hormone synthesis, and degraded or inactivated
hormones are associated with - answer- Hyposecretion
What is the major link between the nervous system and endocrine system - answer-
The hypothalamus
Antidiuretic Hormone controls - answer- Cells at the distal collecting tubule of the kidney
to prevent the secretion of water
Specifically ADH has what effect - answer- It increases aquaporin production by DCT
cells in the distal collecting tubules
ADH decreases - answer- The plamsa osmolality
Syndrome of Innapropriate ADH is - answer- an Inappropriate secretion of ADH in the
absence of normal physiologic stimuli ie thirst
Syndrome of Inappropriate ADH results in - answer- Water retention
Inability of the body to excrete dilute urine
Hypervolemia
Hyponatremia
In SIADH an elevation in ADH level despite low serum sodium level continues to
decrease the plasma concentration resulting in - answer- a shift of more water to the
intracellular space
Cellular edema leads to headache and other neurological signs and symptoms
What is the opposite of SIADH - answer- Diabetes Insipidous
Diabetes Insipidus is caused by - answer- the insufficient release of ADH
Causes patient to excret to much urine
>2.5 L/day
50% 4-8L/Day
25% 8-12L/Day
What are the two types of Diabetes Insipidus - answer- Neurogenic which is more
common
Nephrogenic
,NU 545 Advance Pathophysiology Unit 6
Exam 257 approved and verified Answers.
Neurogenic Diabetes Insipidus can be explained as - answer- Lesion in hypothalamus,
pituitary, or infundibulum resutling in decreased ADH secretion
Nephrogenic Diabetes Insipidus can be explained as - answer- Insesitivity of Renal
tubules to ADH
Hypopituitarism is - answer- An anterior pituitary disorder
Infarction of the gland
Remaoval/destruction of the pituitary
Space occupying pituitary adenomas
Aneurysms that cause compression
Absence of all hormones in the anterior pituitary is called - answer- Panhypopituitarism
Treatment may consist of replacing HGH, ACTH, TSH, and sex hormones
Pituitary dwarfism is caused by - answer- Insufficient HGH release during an individuals
growth phase
In pituitary dwarfism, the patient has - answer- normal face and intelligence, with normal
body proportions
Hyperpituitarism is most common cause of - answer- Pituitary Adenoma
Giantism - answer- Occurs as a result of excess HGH during an individuals growth
phase
Acromegaly - answer- Occurs as a result of excess HGH during adulthood
Acromegaly is marked by the - answer- enlargement and elongation of the bones of the
face, jaw, cheeks, and hands
What is unnafected in acromegaly - answer- The long bones of the extremities are
unaffected because the growth plates are closed
In Acromegaly, with bony and soft tissue overgrowth what can be entrapped - answer-
Nerves
The patient may demonstrate muscle weakness, foot drop, and sensory changes.
Increased size and function of sebaceous and sweat glands increases body odor
Explain the sacs of the thyroid gland - answer- Sacs in the thyroid gland make up most
of the thyroid gland. They are called Thyroid follicles and secret two hormones
Thyroxine T4 and Triodothyronine T3
, NU 545 Advance Pathophysiology Unit 6
Exam 257 approved and verified Answers.
thyroid hormones do what? - answer- REgulate oxygen use
Increase the basal metabolic rate
Increase cellular carbohydrate and protein catabolism
Increase reactivity of the nervous system
Along with HGH, controls tissue growth and development
Hypothyroidism has this effect on cardiac function - answer- Low output Bradycardia
Hyperthryoidism has this effect on cardiac function - answer- increased output
tachycardia
Hypothyroidism has this effect on respiratory function - answer- Hypoventilation
Hyperthyroidism has this effect on respiratory function - answer- Dyspnea
Appearance of Hypothyroidism - answer- Myxedematous
Appearance of Hyperthyroidism - answer- Enlarged thyroid and decreased blinking
What is a goiter - answer- An enlarged thyroid gland due to increase demand for thyroid
hormones
What causes a goiter - answer- Iodine deficiency
Viral or genetic disease
Puberty
PRegnancy
What increases in number due to TSH stimulation and causes a goiter - answer-
Follicles
When can a goiter manifest - answer- During hypothyroidism
Hyperthyroidism
Euthyroidism
GRaves disorder is what? - answer- A automimmune disorder where antibodies are
made against TSH receptors of thyroid cells
In graves disease, the antibodies act as - answer- TSH agonists turning on the
production of thyroxin
Excess thyroxin secretion leads to - answer- Thyrotoxicosis aka symptomatic
hyperthyroidism
