Pediatric CCRN Questions and Correct
Answers | Latest Update
What does SIRS stand for?
✓ -:- Systemic Inflammatory Response Syndrome
Key characteristics of Endotheliopathy
✓ -:- • Capillary leak
• Vasomotor paralysis tone of vessels not normal
• Leukocyte infiltrations
• Coagulopathy
• Myocardial depression
• Immune-compromise
Patient Qualifications of SIRS based off clinical findings.
✓ -:- Two Abnormalities
-Must be abnormalities of temperature (greater than 38 rectal or less than 36 rectal) or
WBC in children
-Other abnormalities include:
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1. HR (Tachycardia)
2. RR (Tachypnea)
3. PaCo2 Less than 32
4. Abnormal WBC>12,000 or less than 4,000
5. WBC bands greater than 10% differential
Management of SIRS
✓ -:- 1. Treat underlying Cause
2.Manage coagulopathies: thrombocytopenia← replace platelet, clot formation← give
thrombolytic, bleeding
3. Mange the endothelipathies: stop inciting insult, fluid resuscitate, increase plasma oncotic
pressure (colloid administration)
4. Promote Vasoconstriction: Alpha Agonist
Septic Shock
✓ -:- - Sepsis plus CV dysfunction: Abnormal perfusion as well as
hypotension.
- Children able to maintain BP longer than Adults
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