BIOS 260 Final Exam with Verified Solutions 100%
Solved
Frederick Griffith conducted the first experiments suggesting that bacteria are capable of
transferring genetic information by performing the following_________? Correct Ans-
Mixing heat-killed smooth-bacteria and their remains with live rough-strain bacteria
Avery, Macleod, and McCarty expanded on Griffith's experiment to prove that DNA is the
hereditary molecule required for transformation. What treatment of the heat-killed smooth-
type bacteria extract resulted no transformation of the rough-bacteria to smooth-type
bacteria? Correct Ans-Destroying smooth-type bacteria extract with DNase
Hershey and Chase used radioactive phosphorus to label which of the macromolecules in the
bacteriophage used in their seminal experiments? Correct Ans-DNA
Hershey and Chase used radioactive sulfur to label which of the macromolecules in the
bacteriophage used in their seminal experiments? Correct Ans-Protein
The key experiment (conducted by Dr. Rosalind Franklin) that Watson and Crick used to
formulate their double helix model of the structure of DNA was__________. Correct Ans-
X-ray crystallography of DNA
, BIOS 260 Final Exam with Verified Solutions 100%
Solved
During replication, the direction of synthesis of new DNA from the leading and lagging strands
is____________. Correct Ans-5' to 3' only
Where does the initiator protein bind DNA at the start of replication? Correct Ans-At an
origin of replication (ORI)
After removal of the RNA primes and the replacement with DNA nucleotides, the single-
stranded nick adjacent to Okazaki fragments is filled in through a reaction that involves which
enzyme? Correct Ans-DNA ligase
Which enzyme elongates the new DNA strand starting at an RNA primer? Correct Ans-DNA
polymerase 3
Which of the following are the two purine nucleotides in DNA? Correct Ans-Adenine and
Guanine
, BIOS 260 Final Exam with Verified Solutions 100%
Solved
Complementary base pairing allows for______________. Correct Ans-DNA to serve as its
own template for replication
If there is 24% guanine in a DNA molecule, then there is __________ thymine Correct Ans-
26%
Recombinant and synthetic human insulin was first produced in which of the following model
genetic organisms?
-Mus Musculus
-Homo sapiens
-Arabidopsis thaliana
-Escherichia coli
-Saccharomyces cervisiae Correct Ans-Escherichia coli
Cytochrome C is a mitochondrial protein that is found in every eukaryotic organism. Why does
alignment of the amino acid sequences from evolutionarily diverse species for this protein
reveal relatively little change:
, BIOS 260 Final Exam with Verified Solutions 100%
Solved
-It is not found in every eukaryotic organism
-Bacteria do not have this protein
-the gene coding for this protein has changed extensively over time
-it is a relatively unimportant protein for eukaryotic function
-it is an essential protein in metabolism of all organisms Correct Ans-it is an essential
protein in metabolism of all organisms
The field of genetics known as ____________ genetics involves studying the structure and
function of genes at the molecular level. Correct Ans-Molecular
How many nucleotide base pairs are in the human genome? Correct Ans-3 billion
The Pax6 gene is found in both humans and fruit flies. Mutations in the gene both result in
eye malformations. This is an example of___________ evolution. Correct Ans-Convergent
In their famous experiment, which of the following would Meselson and Stahl have observed
after one cycle of replication in 14N medium if DNA replication was conservative? Correct
Solved
Frederick Griffith conducted the first experiments suggesting that bacteria are capable of
transferring genetic information by performing the following_________? Correct Ans-
Mixing heat-killed smooth-bacteria and their remains with live rough-strain bacteria
Avery, Macleod, and McCarty expanded on Griffith's experiment to prove that DNA is the
hereditary molecule required for transformation. What treatment of the heat-killed smooth-
type bacteria extract resulted no transformation of the rough-bacteria to smooth-type
bacteria? Correct Ans-Destroying smooth-type bacteria extract with DNase
Hershey and Chase used radioactive phosphorus to label which of the macromolecules in the
bacteriophage used in their seminal experiments? Correct Ans-DNA
Hershey and Chase used radioactive sulfur to label which of the macromolecules in the
bacteriophage used in their seminal experiments? Correct Ans-Protein
The key experiment (conducted by Dr. Rosalind Franklin) that Watson and Crick used to
formulate their double helix model of the structure of DNA was__________. Correct Ans-
X-ray crystallography of DNA
, BIOS 260 Final Exam with Verified Solutions 100%
Solved
During replication, the direction of synthesis of new DNA from the leading and lagging strands
is____________. Correct Ans-5' to 3' only
Where does the initiator protein bind DNA at the start of replication? Correct Ans-At an
origin of replication (ORI)
After removal of the RNA primes and the replacement with DNA nucleotides, the single-
stranded nick adjacent to Okazaki fragments is filled in through a reaction that involves which
enzyme? Correct Ans-DNA ligase
Which enzyme elongates the new DNA strand starting at an RNA primer? Correct Ans-DNA
polymerase 3
Which of the following are the two purine nucleotides in DNA? Correct Ans-Adenine and
Guanine
, BIOS 260 Final Exam with Verified Solutions 100%
Solved
Complementary base pairing allows for______________. Correct Ans-DNA to serve as its
own template for replication
If there is 24% guanine in a DNA molecule, then there is __________ thymine Correct Ans-
26%
Recombinant and synthetic human insulin was first produced in which of the following model
genetic organisms?
-Mus Musculus
-Homo sapiens
-Arabidopsis thaliana
-Escherichia coli
-Saccharomyces cervisiae Correct Ans-Escherichia coli
Cytochrome C is a mitochondrial protein that is found in every eukaryotic organism. Why does
alignment of the amino acid sequences from evolutionarily diverse species for this protein
reveal relatively little change:
, BIOS 260 Final Exam with Verified Solutions 100%
Solved
-It is not found in every eukaryotic organism
-Bacteria do not have this protein
-the gene coding for this protein has changed extensively over time
-it is a relatively unimportant protein for eukaryotic function
-it is an essential protein in metabolism of all organisms Correct Ans-it is an essential
protein in metabolism of all organisms
The field of genetics known as ____________ genetics involves studying the structure and
function of genes at the molecular level. Correct Ans-Molecular
How many nucleotide base pairs are in the human genome? Correct Ans-3 billion
The Pax6 gene is found in both humans and fruit flies. Mutations in the gene both result in
eye malformations. This is an example of___________ evolution. Correct Ans-Convergent
In their famous experiment, which of the following would Meselson and Stahl have observed
after one cycle of replication in 14N medium if DNA replication was conservative? Correct
