NSG 530 EXAM 1 WITH ALL ANSWERS
RATED A+
Interphasev-vcorrectvanswer-
cellvfeeds,vmetabolizesvandvgrowsvwhilevreplicatingvDNAvinvpreparationvforvmitosis
Prophasev-vcorrectvanswer-firstvappearancevofvchromosomesv(willvbev92)
Metaphasev-vcorrectvanswer-
Centriolesvpullvchromosomesvtovoppositevsidesvofvcellv(chromatid)v-v46veachvside
Anaphasev-vcorrectvanswer-
Centromeresvsplitvandvsistervchromatidsvarevpulledvapart
Telophasev-vcorrectvanswer-
Newvnuclearvmembranevformedvaroundveachvgroupvofv46vchromosomesv*Whenvitvg
oesvright,veuploidvcellsvarevproduced*
Nondisjunctionv-vcorrectvanswer-
Errorvinvmeiosisvinvwhichvhomologousvchromosomesvfailvtovseparate.
Polyploidyv-vcorrectvanswer-
conditionvinvwhichvanvorganismvhasvextravsetsvofvchromosomes
Triploidyv-vcorrectvanswer-
whenvanvorganismvhasvthreevcopiesvofveveryvchromsomevinsteadvofvtwo
Tetrapoloidyv-vcorrectvanswer-
euploidvhasv92vchromosomesvandvfetusvusuallyvdoesvnotvsurvive
Huntington'svdiseasev-vcorrectvanswer-
Singlevgenevdisorderv(trinucleotidevrepeatvmutation)
Autosomalvdominantv(50%vchancevofvpassingvitvon)
Progressivevneurologicvdiseasevwithvlatevonsetv(40s)
Prevention-vgeneticvtestingvforvpregnancyvplanning
Cysticvfibrosisv-vcorrectvanswer-Singlevgenevdisorderv(CFTRvgenevmutation)
, Autosomalvrecessive
Mostvcommonvinvwhitevchildren
Defectivevtransportvofvchloridevionsvcausevsaltvimbalance-
vthickenedvsecretions,vdigestivevissues,vmalnutrition.vMalesvandvfemalesv
Mustvinheritvtwovcopiesvofvgenev(1vfromveachvparent)
Turnervsyndromev-vcorrectvanswer-XOvchromosomalvdisorder,vmonosomyvofvX-
affectsvfemales
Shortvstature,vwebbedvneck,vundevelopedvbreastsvbutvfemalevgenitalia,vusuallyvsteril
e
Downvsyndromev-vcorrectvanswer-Chromosomalvdisorder,vtrisomyv21
Affectsvbothvsexes
Intellectualvdisability,vpoorvmusclevtone,vlowvnasalvbridge,vlowvsetvears,vprotrudingvt
ongue,vepicanthalvfold
FragilevXvsyndromev-vcorrectvanswer-
Chromosomalvdisorderv(breakvinvlongvarmvofvX)
Highervprevalencevinvmales
Intellectualvdisability
Klinefeltervsyndromev-vcorrectvanswer-
(XXY)vchromosomalvdisorderv1:1000vmalevbirths
Malevappearance,vsparsevbodyvhair,vmildvintellectualvdisability
Atrophyv-vcorrectvanswer-Decreasevinvcellvsize
"Whenvcastvisvremovedvfromvleftvcalf,vitvisvsmallervthanvthevrightvcalf"
Hypertrophyv-vcorrectvanswer-Increasevinvcellvsize
"Captainvofvrollervderbyvteamvhasvgreatervthighvdiametervatvthevendvofvthevseasonvt
hanvatvthevbeginningvofvthevseason"
Hyperplasiav-vcorrectvanswer-Increasevinvcellvnumber
"Liningvofvuterusvthickensvaftervovulationvbecausevofvincreasedvamountsvofvestrogen
"
"Livervregeneratesvaftervsurgicalvremovalvofvdamagedvportion"
Metaplasiav-vcorrectvanswer-
Reversiblevreplacementvofvonevmaturevcellvtypevbyvanother,vlessvmaturevcellvtypevor
vchangevinvcellvphenotype
"Columnarvepitheliumvinvbronchivofvcigarettevsmokervisvreplacedvbyvstratifiedvsquam
ousvepitheliumvaftervsmokingvcessation"
Dysplasiav-vcorrectvanswer-
Derangedvcellularvgrowth,visvnotvconsideredvavtruevcellularvadaptionvbutvrathervatypi
calvhyperplasia
"CellsvofvthevcervixvcanvbevclassifiedvonvPAPvasvhighvgradevorvlowvgradevdepending
vonvhowvabnormalvthevcellsvhavevbecomevinvsizevandvshape"
RATED A+
Interphasev-vcorrectvanswer-
cellvfeeds,vmetabolizesvandvgrowsvwhilevreplicatingvDNAvinvpreparationvforvmitosis
Prophasev-vcorrectvanswer-firstvappearancevofvchromosomesv(willvbev92)
Metaphasev-vcorrectvanswer-
Centriolesvpullvchromosomesvtovoppositevsidesvofvcellv(chromatid)v-v46veachvside
Anaphasev-vcorrectvanswer-
Centromeresvsplitvandvsistervchromatidsvarevpulledvapart
Telophasev-vcorrectvanswer-
Newvnuclearvmembranevformedvaroundveachvgroupvofv46vchromosomesv*Whenvitvg
oesvright,veuploidvcellsvarevproduced*
Nondisjunctionv-vcorrectvanswer-
Errorvinvmeiosisvinvwhichvhomologousvchromosomesvfailvtovseparate.
Polyploidyv-vcorrectvanswer-
conditionvinvwhichvanvorganismvhasvextravsetsvofvchromosomes
Triploidyv-vcorrectvanswer-
whenvanvorganismvhasvthreevcopiesvofveveryvchromsomevinsteadvofvtwo
Tetrapoloidyv-vcorrectvanswer-
euploidvhasv92vchromosomesvandvfetusvusuallyvdoesvnotvsurvive
Huntington'svdiseasev-vcorrectvanswer-
Singlevgenevdisorderv(trinucleotidevrepeatvmutation)
Autosomalvdominantv(50%vchancevofvpassingvitvon)
Progressivevneurologicvdiseasevwithvlatevonsetv(40s)
Prevention-vgeneticvtestingvforvpregnancyvplanning
Cysticvfibrosisv-vcorrectvanswer-Singlevgenevdisorderv(CFTRvgenevmutation)
, Autosomalvrecessive
Mostvcommonvinvwhitevchildren
Defectivevtransportvofvchloridevionsvcausevsaltvimbalance-
vthickenedvsecretions,vdigestivevissues,vmalnutrition.vMalesvandvfemalesv
Mustvinheritvtwovcopiesvofvgenev(1vfromveachvparent)
Turnervsyndromev-vcorrectvanswer-XOvchromosomalvdisorder,vmonosomyvofvX-
affectsvfemales
Shortvstature,vwebbedvneck,vundevelopedvbreastsvbutvfemalevgenitalia,vusuallyvsteril
e
Downvsyndromev-vcorrectvanswer-Chromosomalvdisorder,vtrisomyv21
Affectsvbothvsexes
Intellectualvdisability,vpoorvmusclevtone,vlowvnasalvbridge,vlowvsetvears,vprotrudingvt
ongue,vepicanthalvfold
FragilevXvsyndromev-vcorrectvanswer-
Chromosomalvdisorderv(breakvinvlongvarmvofvX)
Highervprevalencevinvmales
Intellectualvdisability
Klinefeltervsyndromev-vcorrectvanswer-
(XXY)vchromosomalvdisorderv1:1000vmalevbirths
Malevappearance,vsparsevbodyvhair,vmildvintellectualvdisability
Atrophyv-vcorrectvanswer-Decreasevinvcellvsize
"Whenvcastvisvremovedvfromvleftvcalf,vitvisvsmallervthanvthevrightvcalf"
Hypertrophyv-vcorrectvanswer-Increasevinvcellvsize
"Captainvofvrollervderbyvteamvhasvgreatervthighvdiametervatvthevendvofvthevseasonvt
hanvatvthevbeginningvofvthevseason"
Hyperplasiav-vcorrectvanswer-Increasevinvcellvnumber
"Liningvofvuterusvthickensvaftervovulationvbecausevofvincreasedvamountsvofvestrogen
"
"Livervregeneratesvaftervsurgicalvremovalvofvdamagedvportion"
Metaplasiav-vcorrectvanswer-
Reversiblevreplacementvofvonevmaturevcellvtypevbyvanother,vlessvmaturevcellvtypevor
vchangevinvcellvphenotype
"Columnarvepitheliumvinvbronchivofvcigarettevsmokervisvreplacedvbyvstratifiedvsquam
ousvepitheliumvaftervsmokingvcessation"
Dysplasiav-vcorrectvanswer-
Derangedvcellularvgrowth,visvnotvconsideredvavtruevcellularvadaptionvbutvrathervatypi
calvhyperplasia
"CellsvofvthevcervixvcanvbevclassifiedvonvPAPvasvhighvgradevorvlowvgradevdepending
vonvhowvabnormalvthevcellsvhavevbecomevinvsizevandvshape"
