ACID BASE
BALANCE
DR BILAL KARIM
ASSISTANT PROFESSOR
BIOCHEMISTRY
, ACID BASE BALANCE
• Normal pH = 7.35 – 7.45
• Acidosis; pH = Below 7.35
• Alkalosis; pH = Above 7.45
, ACIDS PRODUCED IN THE BODY
1. Carbonic acid – Produced in course of oxidation in cells.
2. Sulphuric acid – Produced during oxidation of sulphur
containing amino acids.
3. Phosphoric acid – Produced by metabolism of
phosphoproteins, nucleoproteins.
, ACIDS PRODUCED IN THE BODY
• Organic acids – Pyruvic acid, lactic acid, acetoacetic acid, β-
OH butyric acid produced during normal metabolic activity.
• Iatrogenic – Certain medicine like NH₄Cl, Mandelic acid.
BALANCE
DR BILAL KARIM
ASSISTANT PROFESSOR
BIOCHEMISTRY
, ACID BASE BALANCE
• Normal pH = 7.35 – 7.45
• Acidosis; pH = Below 7.35
• Alkalosis; pH = Above 7.45
, ACIDS PRODUCED IN THE BODY
1. Carbonic acid – Produced in course of oxidation in cells.
2. Sulphuric acid – Produced during oxidation of sulphur
containing amino acids.
3. Phosphoric acid – Produced by metabolism of
phosphoproteins, nucleoproteins.
, ACIDS PRODUCED IN THE BODY
• Organic acids – Pyruvic acid, lactic acid, acetoacetic acid, β-
OH butyric acid produced during normal metabolic activity.
• Iatrogenic – Certain medicine like NH₄Cl, Mandelic acid.
