TOX EXAM 2
PRACTICE
QUESTIONS AND
ANSWERS
All are Adverse Effects of Nitrates use except:
a. Headache
b. Postural hypotension
c. Tachycardia
d. All are adverse effects - Answers -D
John is a 63-year-old alcoholic with a 5-year history of ulcers. Recently when self-
medicating for a back condition John
consumed 5 times the recommended daily dose of an over-the-counter pain reliever.
Soon afterwards, John developed a severe
episode of nausea and vomiting. Twelve hours later his wife brings him to the local
Emergency Department. After quizzing
John about the identity of his analgesic, the ER physician draws blood samples for drug
analysis and administers N-Acetyl
Cysteine (NAC) 140 mg/kg orally to prevent further toxicity. What drug did John most
likely take to cause this problem?
a. Acetaminophen (analgesic, Antipyretic)
b. Aspirin (NSAID)
c. Ibuprofen (NSAID)
d. Naproxen (NSAID) - Answers -A
All of the following medication can be useful for managing stable angina in a patient with
non-hypertensive coronary artery
disease except? - Answers -a. Clonidine (centrally acting adrenergic drug)
A 45-year-old man was just started on therapy for hypertension and developed a
persistent, dry cough, which drug is most
, likely responsible for this side effect? - Answers -a. Enalapril (Ace Inhibitor)
Which can produce sedation, drowsiness and difficulties with mental clarity? - Answers -
Clonidine (Centrally acting adrenergic drug)
A 40 year old male has recently been diagnosed with hypertension due to pressure
reading of 163/102 and 165/100 mmHg. He
also has gout. Which is the best initial treatment regimen for treatment of hypertension
in this patient? - Answers -Metoprolol (selective B1-blocker) and Hydrochlorothiazide
(diuretic)
Which may cause reflex tachycardia and/or postural hypotension on initial
administration? - Answers -Prazosin (a-Adrenergic receptor blocking agent)
A 48 year old hypertensive patient has been successfully treated with a thiazide for the
last 5 years. Over the last 3 months his
diastolic pressure the steadily increased and he was started on an additional
antihypertensive agent. He complains of several
instances of being unable to achieve an erection and not being able to complete three
sets of tennis as he once did. Which is the
likely second antihypertensive medication? - Answers -Metoprolol (selective b1-blocker)
Which is an appropriate choice for controlling blood pressure in a pregnant woman with
pre-eclampsia? - Answers -Hydralazine (vasodilator)
Which one of the following is the most common side effect of antihyperlipidemic drug
therapy? - Answers -Gastrointestinal disturbance`
13. A 58 year old female reports that she recently stopped taking her angina
medications because of swelling in her feet that began
shortly after she started treatment. Which is most likely to cause peripheral edema? -
Answers -Nifedipine (ca channel blocker)
14. Which of the following is the treatment of choice for hypothyroidism? - Answers -
Levothyroxine
15. A 65 year old man who presents to his physician for management of hyperlipidemia.
His most recent lipid panel reveals an
LDL cholesterol level of 165 mg/dL (Normal <160 mg/dL). His physician wishes to begin
treatment to lower his LDL
cholesterol levels. Which of the following therapies is the best option to lower his LDL
cholesterol levels? - Answers -Simvastatin
16. A 72 year old male who is treated for hyperlipidemia with high dose atorvastatin for
the past 6 months. He also has a history of
PRACTICE
QUESTIONS AND
ANSWERS
All are Adverse Effects of Nitrates use except:
a. Headache
b. Postural hypotension
c. Tachycardia
d. All are adverse effects - Answers -D
John is a 63-year-old alcoholic with a 5-year history of ulcers. Recently when self-
medicating for a back condition John
consumed 5 times the recommended daily dose of an over-the-counter pain reliever.
Soon afterwards, John developed a severe
episode of nausea and vomiting. Twelve hours later his wife brings him to the local
Emergency Department. After quizzing
John about the identity of his analgesic, the ER physician draws blood samples for drug
analysis and administers N-Acetyl
Cysteine (NAC) 140 mg/kg orally to prevent further toxicity. What drug did John most
likely take to cause this problem?
a. Acetaminophen (analgesic, Antipyretic)
b. Aspirin (NSAID)
c. Ibuprofen (NSAID)
d. Naproxen (NSAID) - Answers -A
All of the following medication can be useful for managing stable angina in a patient with
non-hypertensive coronary artery
disease except? - Answers -a. Clonidine (centrally acting adrenergic drug)
A 45-year-old man was just started on therapy for hypertension and developed a
persistent, dry cough, which drug is most
, likely responsible for this side effect? - Answers -a. Enalapril (Ace Inhibitor)
Which can produce sedation, drowsiness and difficulties with mental clarity? - Answers -
Clonidine (Centrally acting adrenergic drug)
A 40 year old male has recently been diagnosed with hypertension due to pressure
reading of 163/102 and 165/100 mmHg. He
also has gout. Which is the best initial treatment regimen for treatment of hypertension
in this patient? - Answers -Metoprolol (selective B1-blocker) and Hydrochlorothiazide
(diuretic)
Which may cause reflex tachycardia and/or postural hypotension on initial
administration? - Answers -Prazosin (a-Adrenergic receptor blocking agent)
A 48 year old hypertensive patient has been successfully treated with a thiazide for the
last 5 years. Over the last 3 months his
diastolic pressure the steadily increased and he was started on an additional
antihypertensive agent. He complains of several
instances of being unable to achieve an erection and not being able to complete three
sets of tennis as he once did. Which is the
likely second antihypertensive medication? - Answers -Metoprolol (selective b1-blocker)
Which is an appropriate choice for controlling blood pressure in a pregnant woman with
pre-eclampsia? - Answers -Hydralazine (vasodilator)
Which one of the following is the most common side effect of antihyperlipidemic drug
therapy? - Answers -Gastrointestinal disturbance`
13. A 58 year old female reports that she recently stopped taking her angina
medications because of swelling in her feet that began
shortly after she started treatment. Which is most likely to cause peripheral edema? -
Answers -Nifedipine (ca channel blocker)
14. Which of the following is the treatment of choice for hypothyroidism? - Answers -
Levothyroxine
15. A 65 year old man who presents to his physician for management of hyperlipidemia.
His most recent lipid panel reveals an
LDL cholesterol level of 165 mg/dL (Normal <160 mg/dL). His physician wishes to begin
treatment to lower his LDL
cholesterol levels. Which of the following therapies is the best option to lower his LDL
cholesterol levels? - Answers -Simvastatin
16. A 72 year old male who is treated for hyperlipidemia with high dose atorvastatin for
the past 6 months. He also has a history of
