NUR 213 Study Guide – Complete With Precise Answers

NUR 213 Study Guide – Complete With Precise Answers

Contraindications for Antirejection Immunosuppressants Right Ans -
Active infections, lymphoma
Pregnancy, breastfeeding
Concomitant vaccine administration
Renal or hepatic impairment

Tacrolimus and Sirolimus boxed warning Right Ans - infants and children,
clients undergoing liver transplant

Cyclosporine boxed warning Right Ans - systemic hypertension and
nephrotoxicity

Live attenuated vaccines Right Ans - - Contain pathogen that have been
weakened in the laboratory
- No longer able to cause infection
- Still able to trigger protective immune response

Inactivated vaccines Right Ans - - Use a pathogen that has been killed in the
laboratory
- No longer able to replicate or cause infection
- Still able to trigger a protective immune response

Subunit, recombinant, and polysaccharide vaccines Right Ans - Contain just
the portion of pathogen that stimulates the immune response

Conjugated Vaccines Right Ans - Stronger and longer lasting immune
response

Toxoid vaccines Right Ans - Inactivated toxins produced by pathogens
protect against tetanus and diphtheria

mRNA Vaccines Right Ans - - Codes for a harmless viral protein
- Unable to cause disease
- Capable of triggering an immune response

,First generation antihistamines (examples) Right Ans - - chlorpheniramine
- diphenhydramine
- hydroxyzine
- promethazine

Second generation antihistamines (examples) Right Ans - - loratadine
- desloratadine
- fexofenadine
-cetirizine
- levocetirizine

First generation antihistamine Right Ans - - can more easily cross the blood
brain barrier
- Lethargic, can sedate

second generation antihistamines Right Ans - better for use during the day

indications for first generation antihistamines Right Ans - Allergic rhinitis
Allergic conjunctivitis
Urticaria
Anaphylaxis
Common cold
Nausea and vomiting
Motion sickness
Insomnia

Indications for second generation antihistamines Right Ans - Allergic
rhinitis
Allergic conjunctivitis
Urticaria
Anaphylaxis
Common cold

example of methylxanthines Right Ans - theophylline

mechanism of action of theophylline Right Ans - Enters smooth muscles of
the airways and inhibits the enzyme phosphodiesterase, leading to smooth
muscle relaxation

, Theophylline Right Ans - Can be used in asthma and COPD
Bronchial smooth muscle relaxation
Dilation of the narrowed airways and improved air flow

Bronchodilators Right Ans - theophylline is a _____

Mechanism of Biologic Agents -
TNF Blockers (etanercept (Enbrel), infliximab (Remicade, Renflexis,
Avsola, Inflectra), adalimumab (Humira)) Right Ans - Prevent TNF from
attaching to its receptor → suppress immune response

Mechanism of Biologic Agents - IL-1 inhibitor, IL-6 inhibitor, IL-17A inhibitor
(anakinra (Kineret)
tocilizumab (Actemra, Actemra ACTPen)
secukinumab (Cosentyx, Cosentyx Sensoready Pen)) Right Ans - Prevent
IL-1, IL-6, or IL-17A from attaching to their receptors → suppress immune
response

Nursing considerations for inhalers Right Ans - Shake mdi canister
Exhale all air out of the lungs
Put spacer mouthpiece to mouth, make tight seal
Press down in mda
Inhale slowly and deeply, hold breath for 5-10 seconds then fully exhale
If needs more than 1 puff, wait 1 min before 2nd puff
Gargle and rinse the mouth to decrease thrust

Spacer Right Ans - Promotes maximal delivery of medication to lungs

Nursing Considerations for nasal decongestants Right Ans - Assess nasal
passages before administration

Client education for nasal decongestants Right Ans - Gently blow nose
before administration

Report adverse effects, including systemic effects like hypertension or
tachycardia

Tolerance and dependence can develop; use medication for the prescribed
duration