Nurs 3100 Final || Passed!!!

Ulcer correct answers Breakdown of mucosal barrier Gastric Ulcer correct answers Normal amounts of acid secreted OR higher pH (alkaline), decreased synthesis of prostaglandins; common cause (etiology) is H. pylori infection or weak pyloric sphincter (acid breaks down the tight sphincter and makes it weak) and causes the environment to get more basic which also can break down and ulcerate the tissue (bicarb released from duodenum). Duodenal Ulcer correct answers Increased number of parietal cells and gastrin secretion, stimulating the proton pump to make more acid. Because more acid is getting down to duodenum, it alters the pH of the duodenum. Duodenum is more alkaline but the acid is overriding that and offsetting the pH balance there causing things to be acidic in the duodenum. People benefit from antacids h2 blockers PPI's because they need to reduce acid. Triple Anti-infective therapy for Ulcers correct answers 1. Bismuth (pepto-bismol) 2. Metronidazole (Flagyl) 3. Tetracycline (Amoxicillin) Goal: relieve and prevent PAIN and hasten the healing of lesions and prevent recurrences. 5 ulcerogenic substances correct answers 1. Nicotine 2. Alcohol 3. NSAIDs 4. SSRIs 5. Zinc Supplements 6. Systemic corticosteroids All are worse when taken together!!! Functions of the Stomach correct answers Break down of food, stomach acid killing bad organisms, absorbs some nutrients. Functions of the stomach that become impaired with long-term Antacid and/or h2 blocker use correct answers 1. inhibit gastric metabolism of alcohol 2. increase risk of infection 3. decreased absorption of weakly acidic drugs 4. decrease B12 absorption 5. Less efficient protein digestion H-2 Blockers correct answers They block histamine from binding to receptors on parietal cells. Antacids correct answers Neutralize gastric acid. Common antacids: sodium bicarbonate calcium carbonate magnesium hydroxide