NR 324 Final Exam Questions and Well
Defined Terms with Certified Solutions
Methotrexate - ✔Answer- DMARD
Humoral response - ✔Answer- B cells - antibody mediated
Cell mediated - ✔Answer- t cells and CD4, specific antigen recognized
Vaccines - ✔Answer- active immunity
Varicella vaccine - ✔Answer- live vaccine - does not give give vaccine to pt. Who is
immunocompromised
Ige reaction - ✔Answer-
-quick onset
-allergic reaction
-release of mast cells and histamines
-massive vasodilation (shock - BP drops)
-give epi
-mostly concerned about airway - oxygen will not help much since airway is constricting
- have oral airway nearby, then give epi and IV fluids to help with tachycardia and
hypotension
Igg reaction - ✔Answer-
-antibody mediated
-blood transfusion reaction
-hemolytic anemia
, NR 324 Final Exam Questions and Well
Defined Terms with Certified Solutions
Immune Complex Mediated Reaction - ✔Answer-
-inflammatory response
-SLE, Acute glomerular nephritis, RA, hyperacute graft rejection
Hyperacute graft rejection - ✔Answer- -will need to take transplant out
Chronic Rejection - ✔Answer- -s/s: malaise, fatigue, low grade fever, tenderness at graft site,
BUN and creatinine increasing
-give medications for rejection: more immunisuppressants and solumedrol (1000mg IV - watch
blood sugar since it will increase by a large amount)
Cell Mediated Reaction - ✔Answer- -delays, people that get chronic graft rejection or someone
who has a positive PPD, latex allergies, or poison ivy
-
Latex Allergy - ✔Answer- -if pt. Is allergic to bananas, avocados, papayas, they could also be
allergic to latex
Cellular Response with inflammation - ✔Answer- -neutrophils and monocytes go to site of
injury since can now go through capillary walls
Rheumatoid Arthritis - ✔Answer-
-not a joint problem, it is an inflammation of synovial fluid so synovial membrane is
inflamed, then membrane can become fibrotic
-goal for tx: prevent or minimize the # of deformities
-will have ulnar deviation and swan neck deformities
, NR 324 Final Exam Questions and Well
Defined Terms with Certified Solutions
-affects fingers and toes bilaterally a lot
-joints get stiff with limited movement
-morning stiffness that lasts more than hour
-put heat on joints that stiff to relax the joint and increase ROM
-do heat and cold therapy
-dont completely limit movement
-complications: pleural and lung problems, pericarditis, cataracts, contractures, nodules
-get OT AND PT
-ESR: <30%
-CRP: <1 (to see if inflammation is present in body)
-RF: <15 -specific to arthritis
-ANA: positive with RA
Drug Therapy RA - ✔Answer-
-NSAIDS (watch for ulcers)
-COX 2 inhibitors: celebrex
-DMARDS: methotrexate (really bad for kidneys - monitor kidney function throughout
tx.)
-Immune modulators: Embrel, Remicade -> do not take if recently had the flu or
infection
-Corticosteroids: watch for decrease in K and increase in glucose
-NO CURE FOR RA
Defined Terms with Certified Solutions
Methotrexate - ✔Answer- DMARD
Humoral response - ✔Answer- B cells - antibody mediated
Cell mediated - ✔Answer- t cells and CD4, specific antigen recognized
Vaccines - ✔Answer- active immunity
Varicella vaccine - ✔Answer- live vaccine - does not give give vaccine to pt. Who is
immunocompromised
Ige reaction - ✔Answer-
-quick onset
-allergic reaction
-release of mast cells and histamines
-massive vasodilation (shock - BP drops)
-give epi
-mostly concerned about airway - oxygen will not help much since airway is constricting
- have oral airway nearby, then give epi and IV fluids to help with tachycardia and
hypotension
Igg reaction - ✔Answer-
-antibody mediated
-blood transfusion reaction
-hemolytic anemia
, NR 324 Final Exam Questions and Well
Defined Terms with Certified Solutions
Immune Complex Mediated Reaction - ✔Answer-
-inflammatory response
-SLE, Acute glomerular nephritis, RA, hyperacute graft rejection
Hyperacute graft rejection - ✔Answer- -will need to take transplant out
Chronic Rejection - ✔Answer- -s/s: malaise, fatigue, low grade fever, tenderness at graft site,
BUN and creatinine increasing
-give medications for rejection: more immunisuppressants and solumedrol (1000mg IV - watch
blood sugar since it will increase by a large amount)
Cell Mediated Reaction - ✔Answer- -delays, people that get chronic graft rejection or someone
who has a positive PPD, latex allergies, or poison ivy
-
Latex Allergy - ✔Answer- -if pt. Is allergic to bananas, avocados, papayas, they could also be
allergic to latex
Cellular Response with inflammation - ✔Answer- -neutrophils and monocytes go to site of
injury since can now go through capillary walls
Rheumatoid Arthritis - ✔Answer-
-not a joint problem, it is an inflammation of synovial fluid so synovial membrane is
inflamed, then membrane can become fibrotic
-goal for tx: prevent or minimize the # of deformities
-will have ulnar deviation and swan neck deformities
, NR 324 Final Exam Questions and Well
Defined Terms with Certified Solutions
-affects fingers and toes bilaterally a lot
-joints get stiff with limited movement
-morning stiffness that lasts more than hour
-put heat on joints that stiff to relax the joint and increase ROM
-do heat and cold therapy
-dont completely limit movement
-complications: pleural and lung problems, pericarditis, cataracts, contractures, nodules
-get OT AND PT
-ESR: <30%
-CRP: <1 (to see if inflammation is present in body)
-RF: <15 -specific to arthritis
-ANA: positive with RA
Drug Therapy RA - ✔Answer-
-NSAIDS (watch for ulcers)
-COX 2 inhibitors: celebrex
-DMARDS: methotrexate (really bad for kidneys - monitor kidney function throughout
tx.)
-Immune modulators: Embrel, Remicade -> do not take if recently had the flu or
infection
-Corticosteroids: watch for decrease in K and increase in glucose
-NO CURE FOR RA
