INFLAMMATION ,2024

II. INTRODUCTION Definition: Inflammation is a local response (reaction) of living vascularized tissues to endogenous and exogenous stimuli. The term is derived from the Latin "inflammare" meaning to burn. Inflammation is fundamentally destined to localize and eliminate the causative agent and to limit tissue injury. Thus, inflammation is a physiologic (protective) response to injury. Causes Causes of inflammation are apparently causes of diseases such as:  physical agents - mechanical injuries, alteration in temperatures and pressure, radiation injuries.  chemical agents- including the ever increasing lists of drugs and toxins.  biologic agents (infectious)- bacteria, viruses, fungi, parasites  immunologic disorders- hypersensitivity reactions, autoimmunity, immunodeficiency states etc  genetic/metabolic disorders- examples gout, diabetes mellitus etc…