Pathophysiology Exam Paper 1 with Correct Answers

An ordered photographic display of a set of chromosomes from a single cell is a(n): A) metaphase spread. B) autosomal spread. C) karyotype. D) anaphase spread. - Answer -c An error in which homologous chromosomes fail to separate during meiosis is termed: A) aneuploidy. B) nondisjunction. C) polyploidy. D) anaplasia. - Answer -b A somatic cell that does not contain a multiple of 23 chromosomes is called: A) an aneuploid cell. B) a euploid cell. C) a polyploidy cell. D) a haploid cell. - Answer -a A 20-year-old pregnant female gives birth to a stillborn child. Autopsy reveals that the fetus has 92 chromosomes. Which of the following describes this condition? A) Euploidy B) Triploidy C) Tetraploidy D) Aneuploidy - Answer -c If a person is a chromosomal mosaic, the person may: A) be a carrier of the genetic disease. B) have a mild form of the genetic disease. C) have two genetic diseases. D) be sterile as a result of the genetic disease. - Answer -b The most common cause of Down syndrome is: A) paternal nondisjunction. B) maternal translocations. C) maternal nondisjunction. D) paternal translocations. - Answer -c Risk factors for Down syndrome include: A) fetal exposure to mutagens in the uterus. B) increased paternal age. C) family history of Down syndrome. D) pregnancy in women over age 35. - Answer -d