Lipid Digestion and absorption – with accurate answers (verified)Graded A

Triacylglycerols or triglycerides - Answers-What form of lipids is the major component (90%) of human diet? Phospholipids, cholesterols, and free fatty acids. - Answers-Where does the other 10% of lipids in the human diet come from? In the mouth via lingual lipase. - Answers-Where does lipid digestion begin in the body? Lipid digestion occur in the mouth via lingual lipase, in the stomach via lingual lipase and gastric lipase, in the small intestine via pancreatic enzymes and bile salts. Finally absorption occurs in the jejunum. - Answers-Where does lipide digestion and absorption occur? Free fatty acid, Free fatty acid, and monoacylglyceride. - Answers-What are the byproducts of lipase activity on Triacylglycerides? Procolipase is converted to collapse by Trypsin. - Answers-Procolipase is converted by what enzyme? Products are free fatty acids and 2-monoacylglycerides. - Answers-What are the byproducts of Colipase? Phospholipase A2 breaks down phospholipids and requires bile salts. Phospholipase A2 removes fatty acid from sn2 position. - Answers-A small amount of phospholipids are consumed in the diet, how are these molecules broken down? Cholesterol esterase hydrolyzes cholesterol esters to free fatty acids and cholesterol. - Answers-A small amount of cholesterols are consumed in the diet, how are these molecules broken down? Cholesterol is the precursor to bile salt synthesis in the liver. Bile salts are stored in the gall bladder and secreted into bile. - Answers-What is the precursor to bile salts? Bile salts, cholesterols, phospholipids (PC). - Answers-What are the components of the Micelle? Mixed micelles contain Bile salts, cholesterols, phospholipid, lysophospholipid, digestive products, and fat soluble vitamins. - Answers-What are the components of the Mixed Micelle? NPC1L1, SCARB1, CD36. - Answers-What carriers do cholesterols depend on? Many lipids are absorbed via simple diffusion. - Answers-How are the majority of lipids absorbed? ABC transporters - Answers-What transporter pumps out phytosterols (sterols and stannous)? The digestion products of lipolysis are absorbed via the duodenum and jejunum. Bile salts are absorbed in the ileum. - Answers-Where are the digestion products absorbed in the body? Where are bile salts absorbed?