,Table of Contents
Chapter 1: Orientation to PharmacologyTest Bank .................................................................................................. 5
Chapter 2: Application of Pharmacology in Nursing PracticeTest Bank .................................................................. 7
Chapter 3: Drug Regulation, Development, Names, and InformationTest Bank .................................................... 12
Chapter 4: PharmacokineticsTest Bank .................................................................................................................. 15
Chapter 5: PharmacodynamicsTest Bank................................................................................................................ 20
Chapter 6: Drug InteractionsTest Bank ................................................................................................................... 23
Chapter 7: Adverse Drug Reactions and Medication ErrorsTest Bank................................................................... 28
Chapter 8: Individual Variation in Drug ResponsesTest Bank ............................................................................... 34
Chapter 9: Drug Therapy During Pregnancy and Breast-FeedingTest Bank .......................................................... 38
Chapter 10: Drug Therapy in Pediatric PatientsTest Bank ..................................................................................... 42
Chapter 11: Drug Therapy in Geriatric PatientsTest Bank ..................................................................................... 46
Chapter 12: Basic Principles of NeuropharmacologyTest Bank ............................................................................. 51
Chapter 13: Physiology of the Peripheral Nervous SystemTest Bank .................................................................... 55
Chapter 14: Muscarinic Agonists and AntagonistsTest Bank ................................................................................. 59
Chapter 15: Cholinesterase Inhibitors and Their Use in Myasthenia GravisTest Bank .......................................... 63
Chapter 16: Drugs That Block Nicotinic Cholinergic Transmission: NeuromuscularBlocking Agents and
Ganglionic Blocking Agents ................................................................................................................................... 67
Chapter 17: Adrenergic AgonistsTest Bank............................................................................................................ 72
Chapter 18: Adrenergic AntagonistsTest Bank ....................................................................................................... 77
Chapter 19: Indirect-Acting Antiadrenergic AgentsTest Bank ............................................................................... 83
Chapter 20: Introduction to Central Nervous System PharmacologyTest Bank ..................................................... 88
Chapter 21: Drugs for Parkinson’s DiseaseTest Bank ............................................................................................ 91
Chapter 22: Alzheimer’s DiseaseTest Bank............................................................................................................ 97
Chapter 23: Drugs for Multiple SclerosisTest Bank ............................................................................................. 101
Chapter 24: Drugs for EpilepsyTest Bank ............................................................................................................ 106
Chapter 25: Drugs for Muscle Spasm and SpasticityTest Bank............................................................................ 113
Chapter 26: Local AnestheticsTest Bank .............................................................................................................. 117
Chapter 27: General AnestheticsTest Bank........................................................................................................... 122
Chapter 28: Opioid (Narcotic) Analgesics, Opioid Antagonists, and NonopioidCentrally Acting Analgesics .... 127
Chapter 29: Pain Management in Patients with CancerTest Bank........................................................................ 133
Chapter 30: Drugs for HeadacheTest Bank........................................................................................................... 140
Chapter 31: Antipsychotic Agents and Their Use in SchizophreniaTest Bank..................................................... 144
Chapter 32: AntidepressantsTest Bank ................................................................................................................. 150
Chapter 33: Drugs for Bipolar DisorderTest Bank ............................................................................................... 157
Chapter 34: Sedative-Hypnotic DrugsTest Bank .................................................................................................. 162
Chapter 35: Management of Anxiety DisordersTest Bank ................................................................................... 169
Chapter 36: Central Nervous System Stimulants and Attention-Deficit/HyperactivityDisorder ......................... 173
Chapter 37: Drug Abuse I: Basic ConsiderationsTest Bank ................................................................................. 178
Chapter 38: Drug Abuse II: AlcoholTest Bank..................................................................................................... 181
Chapter 39: Drug Abuse III: Nicotine and SmokingTest Bank ............................................................................ 188
,Chapter 40: Drug Abuse IV: Major Drugs of Abuse Other Than Alcohol and NicotineTest Bank...................... 192
Chapter 41: DiureticsTest Bank ............................................................................................................................ 199
Chapter 42: Agents Affecting the Volume and Ion Content of Body FluidsTest Bank ........................................ 204
Chapter 43: Review of HemodynamicsTest Bank ................................................................................................ 210
Chapter 44: Drugs Acting on the Renin-Angiotensin-Aldosterone SystemTest Bank ......................................... 213
Chapter 45: Calcium Channel BlockersTest Bank................................................................................................ 218
Chapter 46: VasodilatorsTest Bank....................................................................................................................... 221
Chapter 47: Drugs for HypertensionTest Bank ..................................................................................................... 225
Chapter 48: Drugs for Heart FailureTest Bank ..................................................................................................... 232
Chapter 49: Antidysrhythmic DrugsTest Bank ..................................................................................................... 240
Chapter 50: Prophylaxis of Coronary Heart Disease: Drugs That Help NormalizeCholesterol and Triglyceride
Levels .................................................................................................................................................................... 248
Chapter 51: Drugs for Angina PectorisTest Bank ................................................................................................. 255
Chapter 52: Anticoagulant, Antiplatelet, and Thrombolytic DrugsTest Bank ...................................................... 261
Chapter 53: Management of ST-Elevation Myocardial InfarctionTest Bank ....................................................... 268
Chapter 54: Drugs for HemophiliaTest Bank ....................................................................................................... 272
Chapter 55: Drugs for Deficiency AnemiasTest Bank.......................................................................................... 276
Chapter 56: Hematopoietic AgentsTest Bank ....................................................................................................... 282
Chapter 57: Drugs for Diabetes MellitusTest Bank .............................................................................................. 286
Chapter 58: Drugs for Thyroid DisordersTest Bank ............................................................................................. 292
Chapter 59: Drugs Related to Hypothalamic and Pituitary FunctionTest Bank ................................................... 298
Chapter 60: Drugs for Disorders of the Adrenal CortexTest Bank ....................................................................... 303
Chapter 61: Estrogens and Progestins: Basic Pharmacology and NoncontraceptiveApplications........................ 308
Chapter 62: Birth ControlTest Bank ..................................................................................................................... 312
Chapter 63: Drug Therapy of InfertilityTest Bank................................................................................................ 318
Chapter 64: Drugs That Affect Uterine FunctionTest Bank ................................................................................. 322
Chapter 65: AndrogensTest Bank ......................................................................................................................... 326
Chapter 66: Drugs for Erectile Dysfunction and Benign Prostatic HyperplasiaTest Bank ................................... 331
Chapter 67: Review of the Immune SystemTest Bank ......................................................................................... 335
Chapter 68: Childhood ImmunizationTest Bank .................................................................................................. 340
Chapter 69: ImmunosuppressantsTest Bank ......................................................................................................... 347
Chapter 70: AntihistaminesTest Bank................................................................................................................... 352
Chapter 71: Cyclooxygenase Inhibitors: Nonsteroidal Anti-inflammatory Drugs andAcetaminophen................ 358
Chapter 72: Glucocorticoids in Nonendocrine DisordersTest Bank ..................................................................... 364
Chapter 73: Drug Therapy of Rheumatoid ArthritisTest Bank ............................................................................. 370
Chapter 74: Drug Therapy of GoutTest Bank ....................................................................................................... 374
Chapter 75: Drugs Affecting Calcium Levels and Bone MineralizationTest Bank .............................................. 378
Chapter 76: Drugs for AsthmaTest Bank .............................................................................................................. 384
Chapter 77: Drugs for Allergic Rhinitis, Cough, and ColdsTest Bank ................................................................. 391
Chapter 78: Drugs for Peptic Ulcer DiseaseTest Bank ......................................................................................... 396
Chapter 79: LaxativesTest Bank ........................................................................................................................... 401
Chapter 80: Other Gastrointestinal DrugsTest Bank............................................................................................. 406
,Chapter 81: VitaminsTest Bank ............................................................................................................................ 414
Chapter 82: Drugs for Weight LossTest Bank ...................................................................................................... 420
Chapter 83: Basic Principles of Antimicrobial TherapyTest Bank ....................................................................... 426
Chapter 84: Drugs That Weaken the Bacterial Cell Wall I: PenicillinsTest Bank ................................................ 432
Chapter 85: Drugs That Weaken the Bacterial Cell Wall II: Cephalosporins, Carbapenems, Vancomycin,
Telavancin, Aztreonam, Teicoplanin, and FosfomycinTest Bank ........................................................................ 438
Chapter 86: Bacteriostatic Inhibitors of Protein Synthesis: Tetracyclines, Macrolides,and Others...................... 443
Chapter 87: Aminoglycosides: Bactericidal Inhibitors of Protein SynthesisTest Bank ........................................ 451
Chapter 88: Sulfonamides and TrimethoprimTest Bank....................................................................................... 458
Chapter 89: Drug Therapy of Urinary Tract InfectionsTest Bank ........................................................................ 463
Chapter 90: Antimycobacterial Agents: Drugs for Tuberculosis, Leprosy, andMycobacterium avium Complex
Infection ................................................................................................................................................................ 469
Chapter 91: Miscellaneous Antibacterial Drugs: Fluoroquinolones, Metronidazole,Daptomycin, Rifampin,
Rifaximin, Bacitracin, and Polymyxins ................................................................................................................ 477
Chapter 92: Antifungal AgentsTest Bank ............................................................................................................. 481
Chapter 93: Antiviral Agents I: Drugs for Non-HIV Viral InfectionsTest Bank ................................................. 489
Chapter 94: Antiviral Agents II: Drugs for HIV Infection and Related OpportunisticInfections ......................... 495
Chapter 95: Drug Therapy of Sexually Transmitted DiseasesTest Bank .............................................................. 501
Chapter 96: Antiseptics and DisinfectantsTest Bank ............................................................................................ 506
Chapter 97: AnthelminticsTest Bank .................................................................................................................... 510
Chapter 98: Antiprotozoal Drugs I: Antimalarial AgentsTest Bank ..................................................................... 514
Chapter 99: Antiprotozoal Drugs II: Miscellaneous AgentsTest Bank ................................................................. 519
Chapter 100: EctoparasiticidesTest Bank.............................................................................................................. 523
Chapter 101: Basic Principles of Cancer ChemotherapyTest Bank ...................................................................... 528
Chapter 102: Anticancer Drugs I: Cytotoxic AgentsTest Bank ............................................................................ 534
Chapter 103: Anticancer Drugs II: Hormonal Agents, Targeted Drugs, and OtherNoncytotoxic Anticancer Drugs
.............................................................................................................................................................................. 541
Chapter 104: Drugs for the EyeTest Bank ............................................................................................................ 546
Chapter 105: Drugs for the SkinTest Bank ........................................................................................................... 552
Chapter 106: Drugs for the EarTest Bank ............................................................................................................. 560
Chapter 107: Miscellaneous Noteworthy DrugsTest Bank ................................................................................... 565
Chapter 108: Dietary SupplementsTest Bank ....................................................................................................... 569
Chapter 109: Management of PoisoningTest Bank............................................................................................... 573
Chapter 110: Potential Weapons of Biologic, Radiologic, and Chemical TerrorismTest Bank ........................... 577
,Chapter 1: Orientation to Pharmacology
Test Bank
MULTIPLE CHOICE
1. The nurse is teaching a patient how a medication works to treat an illness. To do this, the
nurse will rely on knowledge of:
a. clinical pharmacology.
b. drug efficacy.
c. pharmacokinetics.
d. pharmacotherapeutics.
ANS:D
Pharmacotherapeutics is the study of the use of drugs to diagnose, treat, and prevent
conditions. Clinical pharmacology is concerned with all aspects of drug–human interactions.
Drug efficacy measures the extent to which a given drug causes an intended effect.
Pharmacokinetics is the study of the impact of the body on a drug.
DIF: Cognitive Level: Comprehension REF: Four Basic Terms
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
2. What does it mean when a drug is described as easy to administer?
a. It can be stored indefinitely without need for refrigeration.
b. It does not interact significantly with other medications.
c. It enhances patient adherence to the drug regimen.
d. It is usually relatively inexpensive to produce.
ANS:C
A major benefit of drugs that are easy to administer is that patients taking them are more
likely to comply with the drug regimen. Drugs that are easy to give may have the other
attributes listed, but those properties are independent of ease of administration.
DIF: Cognitive Level: Comprehension
REF: Additional Properties of an Ideal Drug: Ease of Administration
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
3. A patient tells the nurse that he was told by the prescriber that the analgesic he is taking is
very effective. Which statement by the patient demonstrates an understanding of the drug’s
effectiveness?
a. “I don’t have to worry about toxicity, since it takes a large amount of this drug to
cause an overdose.”
b. “It has no side effects and doesn’t interact with other drugs.”
c. “I only have to take it every 12 hours.”
d. “It might make me sleepy, and it lessens pain for several hours at a time.”
ANS:D
, A drug is effective if it produces the intended effects, even if it also produces side effects.
Because no drug is completely safe, the level of toxicity does not determine effectiveness. All
drugs have side effects and many react with other substances; these do not affect the drug’s
effectiveness. Ease of administration is independent of a drug’s effectiveness.
DIF: Cognitive Level: Comprehension REF: Properties of an Ideal Drug
TOP: Nursing Process: Evaluation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
MULTIPLE RESPONSE
1. What are the properties of an ideal drug? (Select all that apply.)
a. Irreversible action
b. Predictability
c. Ease of administration
d. Chemical stability
e. A simple trade name
ANS:B, C, D
In addition to predictability, ease of administration, and chemical stability, other properties
include a reversible action so that any harm the drug may cause can be undone and a simple
generic name, because generic names are usually complex and difficult to remember and
pronounce.
DIF: Cognitive Level: Comprehension
REF: Properties of an Ideal Drug | Additional Properties of an Ideal Drug
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
2. Before administering a medication, what does the nurse need to know to evaluate how
individual patient variability might affect the patient’s response to the medication? (Select all
that apply.)
a. Chemical stability of the medication
b. Ease of administration
c. Family medical history
d. Patient’s age
e. Patient’s diagnosis
ANS:C, D, E
The family medical history can indicate genetic factors that may affect a patient’s response to
a medication. Patients of different ages can respond differently to medications. The patient’s
illness can affect how drugs are metabolized. The chemical stability of the medication and the
ease of administration are properties of drugs.
DIF: Cognitive Level: Analysis REF: Sources of Individual Variation
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
Chapter 1: Orientation to PharmacologyTest Bank .................................................................................................. 5
Chapter 2: Application of Pharmacology in Nursing PracticeTest Bank .................................................................. 7
Chapter 3: Drug Regulation, Development, Names, and InformationTest Bank .................................................... 12
Chapter 4: PharmacokineticsTest Bank .................................................................................................................. 15
Chapter 5: PharmacodynamicsTest Bank................................................................................................................ 20
Chapter 6: Drug InteractionsTest Bank ................................................................................................................... 23
Chapter 7: Adverse Drug Reactions and Medication ErrorsTest Bank................................................................... 28
Chapter 8: Individual Variation in Drug ResponsesTest Bank ............................................................................... 34
Chapter 9: Drug Therapy During Pregnancy and Breast-FeedingTest Bank .......................................................... 38
Chapter 10: Drug Therapy in Pediatric PatientsTest Bank ..................................................................................... 42
Chapter 11: Drug Therapy in Geriatric PatientsTest Bank ..................................................................................... 46
Chapter 12: Basic Principles of NeuropharmacologyTest Bank ............................................................................. 51
Chapter 13: Physiology of the Peripheral Nervous SystemTest Bank .................................................................... 55
Chapter 14: Muscarinic Agonists and AntagonistsTest Bank ................................................................................. 59
Chapter 15: Cholinesterase Inhibitors and Their Use in Myasthenia GravisTest Bank .......................................... 63
Chapter 16: Drugs That Block Nicotinic Cholinergic Transmission: NeuromuscularBlocking Agents and
Ganglionic Blocking Agents ................................................................................................................................... 67
Chapter 17: Adrenergic AgonistsTest Bank............................................................................................................ 72
Chapter 18: Adrenergic AntagonistsTest Bank ....................................................................................................... 77
Chapter 19: Indirect-Acting Antiadrenergic AgentsTest Bank ............................................................................... 83
Chapter 20: Introduction to Central Nervous System PharmacologyTest Bank ..................................................... 88
Chapter 21: Drugs for Parkinson’s DiseaseTest Bank ............................................................................................ 91
Chapter 22: Alzheimer’s DiseaseTest Bank............................................................................................................ 97
Chapter 23: Drugs for Multiple SclerosisTest Bank ............................................................................................. 101
Chapter 24: Drugs for EpilepsyTest Bank ............................................................................................................ 106
Chapter 25: Drugs for Muscle Spasm and SpasticityTest Bank............................................................................ 113
Chapter 26: Local AnestheticsTest Bank .............................................................................................................. 117
Chapter 27: General AnestheticsTest Bank........................................................................................................... 122
Chapter 28: Opioid (Narcotic) Analgesics, Opioid Antagonists, and NonopioidCentrally Acting Analgesics .... 127
Chapter 29: Pain Management in Patients with CancerTest Bank........................................................................ 133
Chapter 30: Drugs for HeadacheTest Bank........................................................................................................... 140
Chapter 31: Antipsychotic Agents and Their Use in SchizophreniaTest Bank..................................................... 144
Chapter 32: AntidepressantsTest Bank ................................................................................................................. 150
Chapter 33: Drugs for Bipolar DisorderTest Bank ............................................................................................... 157
Chapter 34: Sedative-Hypnotic DrugsTest Bank .................................................................................................. 162
Chapter 35: Management of Anxiety DisordersTest Bank ................................................................................... 169
Chapter 36: Central Nervous System Stimulants and Attention-Deficit/HyperactivityDisorder ......................... 173
Chapter 37: Drug Abuse I: Basic ConsiderationsTest Bank ................................................................................. 178
Chapter 38: Drug Abuse II: AlcoholTest Bank..................................................................................................... 181
Chapter 39: Drug Abuse III: Nicotine and SmokingTest Bank ............................................................................ 188
,Chapter 40: Drug Abuse IV: Major Drugs of Abuse Other Than Alcohol and NicotineTest Bank...................... 192
Chapter 41: DiureticsTest Bank ............................................................................................................................ 199
Chapter 42: Agents Affecting the Volume and Ion Content of Body FluidsTest Bank ........................................ 204
Chapter 43: Review of HemodynamicsTest Bank ................................................................................................ 210
Chapter 44: Drugs Acting on the Renin-Angiotensin-Aldosterone SystemTest Bank ......................................... 213
Chapter 45: Calcium Channel BlockersTest Bank................................................................................................ 218
Chapter 46: VasodilatorsTest Bank....................................................................................................................... 221
Chapter 47: Drugs for HypertensionTest Bank ..................................................................................................... 225
Chapter 48: Drugs for Heart FailureTest Bank ..................................................................................................... 232
Chapter 49: Antidysrhythmic DrugsTest Bank ..................................................................................................... 240
Chapter 50: Prophylaxis of Coronary Heart Disease: Drugs That Help NormalizeCholesterol and Triglyceride
Levels .................................................................................................................................................................... 248
Chapter 51: Drugs for Angina PectorisTest Bank ................................................................................................. 255
Chapter 52: Anticoagulant, Antiplatelet, and Thrombolytic DrugsTest Bank ...................................................... 261
Chapter 53: Management of ST-Elevation Myocardial InfarctionTest Bank ....................................................... 268
Chapter 54: Drugs for HemophiliaTest Bank ....................................................................................................... 272
Chapter 55: Drugs for Deficiency AnemiasTest Bank.......................................................................................... 276
Chapter 56: Hematopoietic AgentsTest Bank ....................................................................................................... 282
Chapter 57: Drugs for Diabetes MellitusTest Bank .............................................................................................. 286
Chapter 58: Drugs for Thyroid DisordersTest Bank ............................................................................................. 292
Chapter 59: Drugs Related to Hypothalamic and Pituitary FunctionTest Bank ................................................... 298
Chapter 60: Drugs for Disorders of the Adrenal CortexTest Bank ....................................................................... 303
Chapter 61: Estrogens and Progestins: Basic Pharmacology and NoncontraceptiveApplications........................ 308
Chapter 62: Birth ControlTest Bank ..................................................................................................................... 312
Chapter 63: Drug Therapy of InfertilityTest Bank................................................................................................ 318
Chapter 64: Drugs That Affect Uterine FunctionTest Bank ................................................................................. 322
Chapter 65: AndrogensTest Bank ......................................................................................................................... 326
Chapter 66: Drugs for Erectile Dysfunction and Benign Prostatic HyperplasiaTest Bank ................................... 331
Chapter 67: Review of the Immune SystemTest Bank ......................................................................................... 335
Chapter 68: Childhood ImmunizationTest Bank .................................................................................................. 340
Chapter 69: ImmunosuppressantsTest Bank ......................................................................................................... 347
Chapter 70: AntihistaminesTest Bank................................................................................................................... 352
Chapter 71: Cyclooxygenase Inhibitors: Nonsteroidal Anti-inflammatory Drugs andAcetaminophen................ 358
Chapter 72: Glucocorticoids in Nonendocrine DisordersTest Bank ..................................................................... 364
Chapter 73: Drug Therapy of Rheumatoid ArthritisTest Bank ............................................................................. 370
Chapter 74: Drug Therapy of GoutTest Bank ....................................................................................................... 374
Chapter 75: Drugs Affecting Calcium Levels and Bone MineralizationTest Bank .............................................. 378
Chapter 76: Drugs for AsthmaTest Bank .............................................................................................................. 384
Chapter 77: Drugs for Allergic Rhinitis, Cough, and ColdsTest Bank ................................................................. 391
Chapter 78: Drugs for Peptic Ulcer DiseaseTest Bank ......................................................................................... 396
Chapter 79: LaxativesTest Bank ........................................................................................................................... 401
Chapter 80: Other Gastrointestinal DrugsTest Bank............................................................................................. 406
,Chapter 81: VitaminsTest Bank ............................................................................................................................ 414
Chapter 82: Drugs for Weight LossTest Bank ...................................................................................................... 420
Chapter 83: Basic Principles of Antimicrobial TherapyTest Bank ....................................................................... 426
Chapter 84: Drugs That Weaken the Bacterial Cell Wall I: PenicillinsTest Bank ................................................ 432
Chapter 85: Drugs That Weaken the Bacterial Cell Wall II: Cephalosporins, Carbapenems, Vancomycin,
Telavancin, Aztreonam, Teicoplanin, and FosfomycinTest Bank ........................................................................ 438
Chapter 86: Bacteriostatic Inhibitors of Protein Synthesis: Tetracyclines, Macrolides,and Others...................... 443
Chapter 87: Aminoglycosides: Bactericidal Inhibitors of Protein SynthesisTest Bank ........................................ 451
Chapter 88: Sulfonamides and TrimethoprimTest Bank....................................................................................... 458
Chapter 89: Drug Therapy of Urinary Tract InfectionsTest Bank ........................................................................ 463
Chapter 90: Antimycobacterial Agents: Drugs for Tuberculosis, Leprosy, andMycobacterium avium Complex
Infection ................................................................................................................................................................ 469
Chapter 91: Miscellaneous Antibacterial Drugs: Fluoroquinolones, Metronidazole,Daptomycin, Rifampin,
Rifaximin, Bacitracin, and Polymyxins ................................................................................................................ 477
Chapter 92: Antifungal AgentsTest Bank ............................................................................................................. 481
Chapter 93: Antiviral Agents I: Drugs for Non-HIV Viral InfectionsTest Bank ................................................. 489
Chapter 94: Antiviral Agents II: Drugs for HIV Infection and Related OpportunisticInfections ......................... 495
Chapter 95: Drug Therapy of Sexually Transmitted DiseasesTest Bank .............................................................. 501
Chapter 96: Antiseptics and DisinfectantsTest Bank ............................................................................................ 506
Chapter 97: AnthelminticsTest Bank .................................................................................................................... 510
Chapter 98: Antiprotozoal Drugs I: Antimalarial AgentsTest Bank ..................................................................... 514
Chapter 99: Antiprotozoal Drugs II: Miscellaneous AgentsTest Bank ................................................................. 519
Chapter 100: EctoparasiticidesTest Bank.............................................................................................................. 523
Chapter 101: Basic Principles of Cancer ChemotherapyTest Bank ...................................................................... 528
Chapter 102: Anticancer Drugs I: Cytotoxic AgentsTest Bank ............................................................................ 534
Chapter 103: Anticancer Drugs II: Hormonal Agents, Targeted Drugs, and OtherNoncytotoxic Anticancer Drugs
.............................................................................................................................................................................. 541
Chapter 104: Drugs for the EyeTest Bank ............................................................................................................ 546
Chapter 105: Drugs for the SkinTest Bank ........................................................................................................... 552
Chapter 106: Drugs for the EarTest Bank ............................................................................................................. 560
Chapter 107: Miscellaneous Noteworthy DrugsTest Bank ................................................................................... 565
Chapter 108: Dietary SupplementsTest Bank ....................................................................................................... 569
Chapter 109: Management of PoisoningTest Bank............................................................................................... 573
Chapter 110: Potential Weapons of Biologic, Radiologic, and Chemical TerrorismTest Bank ........................... 577
,Chapter 1: Orientation to Pharmacology
Test Bank
MULTIPLE CHOICE
1. The nurse is teaching a patient how a medication works to treat an illness. To do this, the
nurse will rely on knowledge of:
a. clinical pharmacology.
b. drug efficacy.
c. pharmacokinetics.
d. pharmacotherapeutics.
ANS:D
Pharmacotherapeutics is the study of the use of drugs to diagnose, treat, and prevent
conditions. Clinical pharmacology is concerned with all aspects of drug–human interactions.
Drug efficacy measures the extent to which a given drug causes an intended effect.
Pharmacokinetics is the study of the impact of the body on a drug.
DIF: Cognitive Level: Comprehension REF: Four Basic Terms
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
2. What does it mean when a drug is described as easy to administer?
a. It can be stored indefinitely without need for refrigeration.
b. It does not interact significantly with other medications.
c. It enhances patient adherence to the drug regimen.
d. It is usually relatively inexpensive to produce.
ANS:C
A major benefit of drugs that are easy to administer is that patients taking them are more
likely to comply with the drug regimen. Drugs that are easy to give may have the other
attributes listed, but those properties are independent of ease of administration.
DIF: Cognitive Level: Comprehension
REF: Additional Properties of an Ideal Drug: Ease of Administration
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
3. A patient tells the nurse that he was told by the prescriber that the analgesic he is taking is
very effective. Which statement by the patient demonstrates an understanding of the drug’s
effectiveness?
a. “I don’t have to worry about toxicity, since it takes a large amount of this drug to
cause an overdose.”
b. “It has no side effects and doesn’t interact with other drugs.”
c. “I only have to take it every 12 hours.”
d. “It might make me sleepy, and it lessens pain for several hours at a time.”
ANS:D
, A drug is effective if it produces the intended effects, even if it also produces side effects.
Because no drug is completely safe, the level of toxicity does not determine effectiveness. All
drugs have side effects and many react with other substances; these do not affect the drug’s
effectiveness. Ease of administration is independent of a drug’s effectiveness.
DIF: Cognitive Level: Comprehension REF: Properties of an Ideal Drug
TOP: Nursing Process: Evaluation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
MULTIPLE RESPONSE
1. What are the properties of an ideal drug? (Select all that apply.)
a. Irreversible action
b. Predictability
c. Ease of administration
d. Chemical stability
e. A simple trade name
ANS:B, C, D
In addition to predictability, ease of administration, and chemical stability, other properties
include a reversible action so that any harm the drug may cause can be undone and a simple
generic name, because generic names are usually complex and difficult to remember and
pronounce.
DIF: Cognitive Level: Comprehension
REF: Properties of an Ideal Drug | Additional Properties of an Ideal Drug
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
2. Before administering a medication, what does the nurse need to know to evaluate how
individual patient variability might affect the patient’s response to the medication? (Select all
that apply.)
a. Chemical stability of the medication
b. Ease of administration
c. Family medical history
d. Patient’s age
e. Patient’s diagnosis
ANS:C, D, E
The family medical history can indicate genetic factors that may affect a patient’s response to
a medication. Patients of different ages can respond differently to medications. The patient’s
illness can affect how drugs are metabolized. The chemical stability of the medication and the
ease of administration are properties of drugs.
DIF: Cognitive Level: Analysis REF: Sources of Individual Variation
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
