Unit 6a applied science complete
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Unit 6A: Preparation of Phenyl Benzoate.
P:
Phenyl benzoate is a benzoate ester obtained by the formal condensation
of phenol with benzoic acid. It is a crystalline powder with a melting point of
68-70° C (lit.) and a boiling point of 298-299° C (lit.). Phenyl benzoate is an
organic compound which is used as a medication and insect repellent. As a
medication it is used to effectively treat scabies and lice.
The Schotten-Baumann Reaction Mechanism:
The Schotten–Baumann reaction is a method to synthesize amides from
amines and acid chlorides: Schotten–Baumann reaction also refers to the
conversion of acid chloride to esters. Phenyl benzoate is prepared by the
Schotten-Baumann method for benzoylation. In this method of benzoylation
phenols are reacted with benzoyl chloride in presence of aqueous sodium
hydroxide and the reaction mixture is shaken vigorously. The solid benzoyl
compound (being insoluble in water) separates out. Phenol is then subjected
to the Schotten-Baumann benzoylation. Benzoyl chloride is added for
benzoylation.
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RISK ASSESSMENT FORM
Name of assessor:- Najah Bendriss
Date: 17/05/2021
Activity:-
Synthesis of Phenyl benzoate from phenol.
Hazards
Glass
Sodium hydroxide (corrosive)
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assignment
written by
najbo123
www.stuvia.com
Downloaded by: najbo123 | Want to earn £756
Distribution of this document is illegal extra per year?
, Stuvia.co.uk - The Marketplace for Revision Notes & Study Guides
Unit 6A: Preparation of Phenyl Benzoate.
P:
Phenyl benzoate is a benzoate ester obtained by the formal condensation
of phenol with benzoic acid. It is a crystalline powder with a melting point of
68-70° C (lit.) and a boiling point of 298-299° C (lit.). Phenyl benzoate is an
organic compound which is used as a medication and insect repellent. As a
medication it is used to effectively treat scabies and lice.
The Schotten-Baumann Reaction Mechanism:
The Schotten–Baumann reaction is a method to synthesize amides from
amines and acid chlorides: Schotten–Baumann reaction also refers to the
conversion of acid chloride to esters. Phenyl benzoate is prepared by the
Schotten-Baumann method for benzoylation. In this method of benzoylation
phenols are reacted with benzoyl chloride in presence of aqueous sodium
hydroxide and the reaction mixture is shaken vigorously. The solid benzoyl
compound (being insoluble in water) separates out. Phenol is then subjected
to the Schotten-Baumann benzoylation. Benzoyl chloride is added for
benzoylation.
Downloaded by: najbo123 | Want to earn £756
Distribution of this document is illegal extra per year?
, Stuvia.co.uk - The Marketplace for Revision Notes & Study Guides
RISK ASSESSMENT FORM
Name of assessor:- Najah Bendriss
Date: 17/05/2021
Activity:-
Synthesis of Phenyl benzoate from phenol.
Hazards
Glass
Sodium hydroxide (corrosive)
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Distribution of this document is illegal extra per year?
