Nurs 6501 Advanced Pathophysiology - Exam (Neuro) with verified accurate answers available

Lambert-Eaton Syndrome - ANSA syndrome caused by autoantibodies that inhibit the function of presynaptic calcium channels, leading to decreased release of acetylcholine into the synaptic cleft Lambert-Eaton - Clinical Manifestations - ANS*Strong link to lung cancer *Muscle weakness that IMPROVES with repetitive stimulation *Do not respond to cholinesterase inhibitors Spinal cord trauma - patho - ANS*Microscopic hemorrhages in central grey matter *Axonal edema in white matter --> ischemia --> injury and degeneration *Release inflammatory mediators -->necrosis and scar tissue formation *Injury is maximal at injury site and two cord segments above and below it Spinal cord trauma - Clinical manifestations - ANS*Spinal shock (normal activity of the spinal cord stops at and below level of injury. Loss of spinal reflexes.) *Paraplegia, quadriplegia *Autonomic dysreflexia Brown-Sequard Syndrome - ANSOccurs when there is trauma or lesion that affects one half of the spinal cord. Typically occurs in the cervical region. Brown-Sequard Syndrome - Clinical Manifestations - ANS*Loss of proprioception on the SAME side as the lesion *Loss of voluntary motor function from the corticospinal tract on the SAME side as the lesion *Loss of pain and temperature on the OPPOSITE side of the lesion