Comprehensive Basic Science Exam (CBSE) Review Set I (solved)

Chagas Disease correct answers Caused by Trypanosoma cruzi parasite passed in the feces of Reduviidae/kissing bug Penetrates broken skin or intact mucous membranes forming a pseudocyst releasing inflammatory infiltrates into myocytes; stains with Giemsa & Wright Romana sign occurs when portal of entry is the conjunctiva or eyelid May resulting in: Enlarged heart- CHF, sudden cardiac arrest Enlarged esophagus- difficulty swallowing Enlarged colon- abdominal pain or constipation Treat with benznidazole or nifurtimox Monocytes correct answers cell with half-moon shaped nucleus that participates in phagocytosis Chronic graft rejection correct answers multifactorial but typically involves arteriosclerosis HLA-B27 correct answers PAIR: Psoriasis Ankylosing spondylitis- chronic synovitis destroying cartilage typically in young men Inflammatory bowel dz- Crohn's & UC Reactive Arthritis- Reactive Arthritis correct answers Arthritis as a reaction to a bacterial infection such as Campylobacter, Chlamydia, Salmonella, Shigella, or Ureaplasma. Associated with conjunctivitis & uveitis Gaucher (Type 1) correct answers AR Lysosomal storage disease Accumulation of sphingolipid glucocerebroside Most common Wrinkled tissue paper