Ascp Mls Coagulation Questions With Complete Solutions

What is produced from megakaryocytes? Correct Answer: platelets Life span of platelets Correct Answer: 9-12 days Distribution of platelets Correct Answer: 30% spleen 70% peripheral blood What factors are vitamin k dependent? Correct Answer: 1927 (10, 9, 2, 7, Protein C, and protein S) Which factors are consumed in clotting? Correct Answer: I II V VIII XIII What factors in the intrinsic pathway? Correct Answer: XII XI IX VIII What factors are in the extrinsic pathway? Correct Answer: VII What factors are in the common pathway? Correct Answer: X V II I What test monitors the intrinsic pathway? Correct Answer: APTT What test monitors the extrinsic pathway? Correct Answer: PT What are the three commonly used "clotbusters"? Correct Answer: streptokinase, urokinase, TPA What specimen is used for coagulation tests? Correct Answer: Sodium citrate What reagent is used in PT? Correct Answer: tissue thromboplasti and CaCl2 What test monitors oral anticoagulants such as warfarin, coumarin, and dicoumarol? Correct Answer: PT Reference range for PT Correct Answer: 13 seconds INR=2.0-3.5 What is th formula for INR? Correct Answer: (patient results/mean of reference range)^ISI What factors does PTT not measure? Correct Answer: VII and XIII What reagents are used for PTT? Correct Answer: Activator (kaolin, celite, or ellagic acid) platelet phospholipid, and CaCl2 What drug is monitored by PTT? Correct Answer: Heparin