Msn 571 Pharm Midterm Exam 1 Answers Latest Rated A+

MSN 571 PHARM MIDTERM EXAM 1 ANSWERS LATEST RATED A+ 1. Why are most statins recommended to be taken in the evening?  Can cause insomnia  Decreases stomach upset  Cholesterol synthesis increases during the night  Cholesterol synthesis decreases during the night 2. What is the mechanism of action of ezetimibe?  It inhibits the absorption of bile, thus causing the liver to produce bile from cholesterol.*  It decreases the adhesion of cholesterol on the arterial walls.  It inhibits absorption of dietary and biliary cholesterol in the small intestine.  (option cutoff) 3. Which of the following is not an expected adverse effect of Niacin?  Arthralgias  Hyperglycemia  Itching  Flushing 4. Which adverse effects would you monitor for a patient receiving a statin to manage cholesterol levels. Select all that apply.  Gallstone development  Increased serum transaminase levels  Unexplained muscle pain or tenderness *  Nonalcoholic fatty liver disease *  Elevated creatinine kinase (CK) level with muscle pain * 5. Which of the following drug classes should be avoided in peptic ulcer disease?  Avoid diuretics  Avoid NSAIDS  Avoid proton pump inhibitors  Avoid antibiotics 6. Which of the following groups of antibiotics is notable for side effects such as nephrotoxicity and ototoxicity?  Cephalosporins  Beta-lactams  Aminoglycoside  Tetracyclines 7. Which of the following is most likely an intervention for otitis media?  Corticosteroids  Aspirin  Immunoglobulins  Amoxicillin 8. Which of the following medications is a fluoroquinolone antibiotic?  Penicillin  Azithromycin  Amikacin  Ciprofloxacin 9. Which of the following best classifieds aminoglycosides, macrolides, and clindamycin?  mycolic acid synthesis inhibitors  protein synthesis inhibitors  cell wall inhibitors  folic acid synthesis inhibitors 10. Which of the following groups of antibiotics binds to the 50S subunit of the bacterial ribosome and includes drugs such as erythromycin and azithromycin?  macrolides  fluoroquinolones  aminoglycosides  tetracyclines 11. Which of the following groups of people are at risk for early hypertension?  African American  Adolescents or young adults  Mexican American Culture  Old females 12. Which of the following drug treatment strategies is associated with peptic ulcer disease?  Opioids  Two antibiotics  Corticosteroids  Hormonal therapy 13. Which of the following medications or drug classes is commonly indicated for managing gestational hypertension?  Spironolactone (Aldactone)  Loop diuretics  Calcium channel blockers  Dobutamine  Calcium gluconate 14. Which antibiotic class disrupts folate metabolism in bacteria and is often combined with trimethoprim?  cephalosporins  fluoroquinolones  Aminoglycosides  Sulfonamides  macrolides 15. Convert 15 lbs 8 oz to kilograms. Round to the nearest 100th.  7.00  34.10  33.00  7.03 16. A patient receiving intravenous gentamicin has a toxic serum drug level. The prescriber confirms that the dosing is correct. Which possible cause of the situation will the provider explore?  Whether patient is taking a medication that binds to serum albumin  Whether a loading dose was administered  If the ordered dose frequency is longer than the gentamicin half-life  If the drug was completely dissolved in the IV solution 17. The therapeutic index is a measure of drug:  Absorption rate  Safety profile  Bioavailability status  Effectiveness 18. Which science provides primary healthcare providers the opportunity to individualize drug therapy based on a patient's genetic makeup?  Pharmacogenetics  Pharmacogenomics *  Pharmacodynamics  Pharmacokinetics 19. Which of the following is the most appropriate choice to describe age associated changes that can affect pharmacokinetics in older patients?  Increase in total body water  Decrease in creatinine clearance  (option cutoff)  (option cutoff) 20. Drugs that use CYP 3A4 enzymes for metabolism may:  None of the answers are correct  Induce the metabolism of another drug  Inhibit the metabolism of another drug *  Both induce and inhibit the metabolism of another drug. 21. An example of a first-d