OpenStax Microbiology Test Bank
Chapter 10: Biochemistry of the Genome
Chapter 10: Biochemistry of the Genome
* = Correct answer
Multiple Choice
1. Gregor Mendel conducted his revolutionary work on patterns of inheritance using which
organism?
A. fruit flies
B. pea plants*
C. roundworms
D. snapdragons
Difficulty: Easy
ASM Standard: N/A
2. Which best describes true-breeding organisms?
A. They are heterozygous at multiple loci.
B. They have been produced through hybridization.
C. They produce offspring identical to themselves when self-fertilized.*
D. They produce offspring of the same species when self-fertilized.
Difficulty: Easy
ASM Standard: N/A
3. In a monohybrid cross, the first generation of offspring is called which of the following?
A. dihybrid generation
B. first filial generation*
C. parental generation
D. second filial generation
Difficulty: Easy
ASM Standard: N/A
4. When Mendel published his work, most people believed which of the following about
inheritance?
A. A fully formed, miniature human was transmitted from the father.
B. Blending of traits from both parents produces the traits of the offspring.*
C. Genes are transmitted in DNA.
D. Information from the mother provides the entire blueprint for the offspring.
Difficulty: Easy
ASM Standard: N/A
5. A DNA nucleotide contains which of the following?
Page 1 of 16
,OpenStax Microbiology Test Bank
Chapter 10: Biochemistry of the Genome
A. a deoxyribose sugar and a nitrogenous base
B. a deoxyribose sugar, a phosphate, and a nitrogenous base*
C. a ribose sugar and a nitrogenous base
D. a ribose sugar, a phosphate, and a nitrogenous base
Difficulty: Easy
ASM Standard: N/A
6. A nucleoside contains which of the following components?
A. a phosphate and a base
B. a phosphate and a sugar
C. a sugar and a base*
D. a sugar, a phosphate, and a base
Difficulty: Easy
ASM Standard: N/A
7. Which of the following is a name for nitrogenous bases with a double-ring structure?
A. nucleosides
B. nucleotides
C. purines*
D. pyrimidines
Difficulty: Easy
ASM Standard: N/A
8. Where in the DNA structure do DNA-binding proteins generally bind?
A. in the center of the helix, between the bases
B. in the major grooves
C. in the minor grooves
D. in the major and minor grooves*
Difficulty: Easy
ASM Standard: N/A
9. Which of the following is not an example of an organism’s phenotype?
A. a behavioral response to certain conditions
B. an organism’s observable characteristics
C. the DNA sequence of a cellular genome*
D. which enzymes are being synthesized
Difficulty: Moderate
ASM Standard: N/A
10. Who identified the nucleotide bases of DNA and RNA?
A. Richard Altmann
B. Albrecht Kossel*
Page 2 of 16
, OpenStax Microbiology Test Bank
Chapter 10: Biochemistry of the Genome
C. Gregor Mendel
D. Friedrich Miescher
Difficulty: Moderate
ASM Standard: N/A
11. Mendel published his work in which of the following books?
A. Experiments in Plant Hybridization*
B. On the Origin of Species
C. The Double Helix
D. The Physical Basis of Heredity
Difficulty: Moderate
ASM Standard: N/A
12. Whose work provided the first experimental evidence for the Chromosomal Theory of
Inheritance?
A. Theodor Boveri’s work with sea urchins
B. Barbara McClintock’s work with maize
C. Gregor Mendel’s work with pea plants
D. Thomas Hunt Morgan’s work with Drosophila*
Difficulty: Moderate
ASM Standard: N/A
13. Which alga provided an important model to demonstrate the location of genetic information
in the nucleus?
A. Acetabularia*
B. Chlamydomonas
C. Ulva
D. Volvox
Difficulty: Moderate
ASM Standard: N/A
14. The one gene–one enzyme hypothesis that developed into the one gene–one polypeptide
hypothesis was proposed by which of the following?
A. George Beadle, Edward Tatum, and colleagues*
B. Gregor Mendel
C. Matthew Meselson and Franklin Stahl
D. Thomas Hunt Morgan
Difficulty: Easy
ASM Standard: N/A
15. Evidence that DNA was the genetic material rather than protein was provided by which of
the following?
Page 3 of 16
Chapter 10: Biochemistry of the Genome
Chapter 10: Biochemistry of the Genome
* = Correct answer
Multiple Choice
1. Gregor Mendel conducted his revolutionary work on patterns of inheritance using which
organism?
A. fruit flies
B. pea plants*
C. roundworms
D. snapdragons
Difficulty: Easy
ASM Standard: N/A
2. Which best describes true-breeding organisms?
A. They are heterozygous at multiple loci.
B. They have been produced through hybridization.
C. They produce offspring identical to themselves when self-fertilized.*
D. They produce offspring of the same species when self-fertilized.
Difficulty: Easy
ASM Standard: N/A
3. In a monohybrid cross, the first generation of offspring is called which of the following?
A. dihybrid generation
B. first filial generation*
C. parental generation
D. second filial generation
Difficulty: Easy
ASM Standard: N/A
4. When Mendel published his work, most people believed which of the following about
inheritance?
A. A fully formed, miniature human was transmitted from the father.
B. Blending of traits from both parents produces the traits of the offspring.*
C. Genes are transmitted in DNA.
D. Information from the mother provides the entire blueprint for the offspring.
Difficulty: Easy
ASM Standard: N/A
5. A DNA nucleotide contains which of the following?
Page 1 of 16
,OpenStax Microbiology Test Bank
Chapter 10: Biochemistry of the Genome
A. a deoxyribose sugar and a nitrogenous base
B. a deoxyribose sugar, a phosphate, and a nitrogenous base*
C. a ribose sugar and a nitrogenous base
D. a ribose sugar, a phosphate, and a nitrogenous base
Difficulty: Easy
ASM Standard: N/A
6. A nucleoside contains which of the following components?
A. a phosphate and a base
B. a phosphate and a sugar
C. a sugar and a base*
D. a sugar, a phosphate, and a base
Difficulty: Easy
ASM Standard: N/A
7. Which of the following is a name for nitrogenous bases with a double-ring structure?
A. nucleosides
B. nucleotides
C. purines*
D. pyrimidines
Difficulty: Easy
ASM Standard: N/A
8. Where in the DNA structure do DNA-binding proteins generally bind?
A. in the center of the helix, between the bases
B. in the major grooves
C. in the minor grooves
D. in the major and minor grooves*
Difficulty: Easy
ASM Standard: N/A
9. Which of the following is not an example of an organism’s phenotype?
A. a behavioral response to certain conditions
B. an organism’s observable characteristics
C. the DNA sequence of a cellular genome*
D. which enzymes are being synthesized
Difficulty: Moderate
ASM Standard: N/A
10. Who identified the nucleotide bases of DNA and RNA?
A. Richard Altmann
B. Albrecht Kossel*
Page 2 of 16
, OpenStax Microbiology Test Bank
Chapter 10: Biochemistry of the Genome
C. Gregor Mendel
D. Friedrich Miescher
Difficulty: Moderate
ASM Standard: N/A
11. Mendel published his work in which of the following books?
A. Experiments in Plant Hybridization*
B. On the Origin of Species
C. The Double Helix
D. The Physical Basis of Heredity
Difficulty: Moderate
ASM Standard: N/A
12. Whose work provided the first experimental evidence for the Chromosomal Theory of
Inheritance?
A. Theodor Boveri’s work with sea urchins
B. Barbara McClintock’s work with maize
C. Gregor Mendel’s work with pea plants
D. Thomas Hunt Morgan’s work with Drosophila*
Difficulty: Moderate
ASM Standard: N/A
13. Which alga provided an important model to demonstrate the location of genetic information
in the nucleus?
A. Acetabularia*
B. Chlamydomonas
C. Ulva
D. Volvox
Difficulty: Moderate
ASM Standard: N/A
14. The one gene–one enzyme hypothesis that developed into the one gene–one polypeptide
hypothesis was proposed by which of the following?
A. George Beadle, Edward Tatum, and colleagues*
B. Gregor Mendel
C. Matthew Meselson and Franklin Stahl
D. Thomas Hunt Morgan
Difficulty: Easy
ASM Standard: N/A
15. Evidence that DNA was the genetic material rather than protein was provided by which of
the following?
Page 3 of 16
