Stroke rehabilitation
Introduction
BEFAST:
❗ Key symptoms to recognize a stroke:
Risk factors for stroke:
❗ Stress is not evidence based, but this can lead to another risk factor.
→ Some are modifiable by behavioral or medication.
1. Diabetes.
2. High blood pressure.
3. Hormones.
4. Obesity.
5. Inactivity.
6. Binge drinking.
7. Smoking.
8. Age.
Stroke rehabilitation 1
, 9. Previous stroke.
10. Family history.
11. Heart disease.
12. High cholesterol.
Studies: different phases:
1. Phase I: pilot study on small group without controls and looking at outcome.
❗ Looking for a potential improvement.
2. Phase II: show safety and feasibility as a base for phase III.
❗ This shows no effectiveness = underpowered.
3. Phase III: shows effectiveness.
❗ Often publication bias = not publishing because it does not give
the results you want.
MAGIC app = clinical guidelines.
Living guidelines = continuous changing and being updated.
BUT it does not tell you how to do this.
Outcomes
mRS = modified rank scale.
0 - 6 met 0 no symptoms and 6 is dead.
Stroke rehabilitation 2
Introduction
BEFAST:
❗ Key symptoms to recognize a stroke:
Risk factors for stroke:
❗ Stress is not evidence based, but this can lead to another risk factor.
→ Some are modifiable by behavioral or medication.
1. Diabetes.
2. High blood pressure.
3. Hormones.
4. Obesity.
5. Inactivity.
6. Binge drinking.
7. Smoking.
8. Age.
Stroke rehabilitation 1
, 9. Previous stroke.
10. Family history.
11. Heart disease.
12. High cholesterol.
Studies: different phases:
1. Phase I: pilot study on small group without controls and looking at outcome.
❗ Looking for a potential improvement.
2. Phase II: show safety and feasibility as a base for phase III.
❗ This shows no effectiveness = underpowered.
3. Phase III: shows effectiveness.
❗ Often publication bias = not publishing because it does not give
the results you want.
MAGIC app = clinical guidelines.
Living guidelines = continuous changing and being updated.
BUT it does not tell you how to do this.
Outcomes
mRS = modified rank scale.
0 - 6 met 0 no symptoms and 6 is dead.
Stroke rehabilitation 2