ADVANCED PHARM EXAM 1
PRACTICE QUESTIONS WITH
COMPLETE SOLUTIONS
◉ Which of the following create a higher risk for digoxin toxicity?
Both the cause and the reason for it must be correct.
A. Older adults because of reduced renal function
B. Administration of aldosterone antagonist diuretics because of
decreased potassium levels
C. Taking an antacid for gastroesophageal reflux disease because it
increases the absorption of digoxin
D. Doses between 0.25 and 0.5 mg/day
Answer: A. Older adults because of reduced renal function
◉ Jacob has hypertension, for which a calcium channel blocker has
been prescribed. This drug helps control blood pressure because it:
A. Decreases the amount of calcium inside the cell
B. Reduces stroke volume
C. increases the activity of the na+/K+/ATPase pump indirectly
D. Decreases HR
Answer: A. Decreases the amount of calcium inside the cell
,◉ Which of the following medications places a patient at increased
risk of developing chronic kidney disease?
A. Ranitidine
B. Omeprazole
C. Loperamide
D. Ondansetron
Answer: B. Omeprazole
◉ Which precautions are shared with family members who will be
assisting the patient with application of nitro patches?
Answer: Wear gloves to prevent getting a headache
◉ Which comment by a patient indicates a need for more education
concerning his nitrate medication?
Answer: "I keep a tablet on the bedside table in case I awaken with
chest pain."
◉ A potentially life-threatening adverse response to an ACE
inhibitor is angioedema. Which of the following statements is true
about this adverse response?
Answer: Swelling of the tongue and hoarseness are the most
common symptoms.
◉ Commercials on TV for erectile dysfunction (ED) medications
warn about mixing them with nitrates. Why?
, a. increased risk of priapism.
b. profound hypotension.
c. development of blue discoloration to the visual field.
d. inactivation of the ED medication effect.
Answer: b. profound hypotension.
◉ While taking an angiotensin II receptor blocker (ARB), patients
need to avoid certain over-the-counter drugs without first
consulting the provider because:
a. cimetidine is metabolized by the CYP3A4 isoenzymes.
b. nonsteroidal anti-inflammatory drugs reduce prostaglandin
levels.
c. both 1 and 2.
d. neither 1 nor 2
Answer: c. both 1 and 2.
◉ Jacob has hypertension, for which a calcium channel blocker has
been prescribed. This drug helps control blood pressure because it:
a. decreases the amount of calcium inside the cell.
b. reduces stroke volume.
c. increases the activity of the Na+/K+/ATPase pump indirectly.
PRACTICE QUESTIONS WITH
COMPLETE SOLUTIONS
◉ Which of the following create a higher risk for digoxin toxicity?
Both the cause and the reason for it must be correct.
A. Older adults because of reduced renal function
B. Administration of aldosterone antagonist diuretics because of
decreased potassium levels
C. Taking an antacid for gastroesophageal reflux disease because it
increases the absorption of digoxin
D. Doses between 0.25 and 0.5 mg/day
Answer: A. Older adults because of reduced renal function
◉ Jacob has hypertension, for which a calcium channel blocker has
been prescribed. This drug helps control blood pressure because it:
A. Decreases the amount of calcium inside the cell
B. Reduces stroke volume
C. increases the activity of the na+/K+/ATPase pump indirectly
D. Decreases HR
Answer: A. Decreases the amount of calcium inside the cell
,◉ Which of the following medications places a patient at increased
risk of developing chronic kidney disease?
A. Ranitidine
B. Omeprazole
C. Loperamide
D. Ondansetron
Answer: B. Omeprazole
◉ Which precautions are shared with family members who will be
assisting the patient with application of nitro patches?
Answer: Wear gloves to prevent getting a headache
◉ Which comment by a patient indicates a need for more education
concerning his nitrate medication?
Answer: "I keep a tablet on the bedside table in case I awaken with
chest pain."
◉ A potentially life-threatening adverse response to an ACE
inhibitor is angioedema. Which of the following statements is true
about this adverse response?
Answer: Swelling of the tongue and hoarseness are the most
common symptoms.
◉ Commercials on TV for erectile dysfunction (ED) medications
warn about mixing them with nitrates. Why?
, a. increased risk of priapism.
b. profound hypotension.
c. development of blue discoloration to the visual field.
d. inactivation of the ED medication effect.
Answer: b. profound hypotension.
◉ While taking an angiotensin II receptor blocker (ARB), patients
need to avoid certain over-the-counter drugs without first
consulting the provider because:
a. cimetidine is metabolized by the CYP3A4 isoenzymes.
b. nonsteroidal anti-inflammatory drugs reduce prostaglandin
levels.
c. both 1 and 2.
d. neither 1 nor 2
Answer: c. both 1 and 2.
◉ Jacob has hypertension, for which a calcium channel blocker has
been prescribed. This drug helps control blood pressure because it:
a. decreases the amount of calcium inside the cell.
b. reduces stroke volume.
c. increases the activity of the Na+/K+/ATPase pump indirectly.
