Pharm 615 Test 4 Questions with Verified Correct
Answer
A patient in the emergency room (ER) has been prescribed ondansetron for nausea. The
APN understands that this medication works by which mechanism?
1 ] Blocking dopamine receptors in the chemoreceptor trigger zone
2 ] Blocking histamine1 receptors in the gastrointestinal (GI) tract
3 ] Blocking serotonin on vagal nerve terminals
4 ] Stimulating gastric emptying and peristalsis
3. Blocking serotonin on vagal nerve terminals
Which classification of respiratory medications results in bronchodilation effects and
sputum volume reduction in patients with chronic obstructive pulmonary disease (COPD)?
1 ] Beta2 agonists
2 ] Methylxanthines
3 ] Muscarinic agents
4 ] Phosphodiesterase-4 (PDE-4) inhibitors
3. Muscarinic agents reduce the volume of sputum without changing the viscosity, in addition to
their bronchodilation effects.
Which condition is a clinical indication for antihistamines?
1 ] Nervousness
, 2 ] Headache
3 ] Urticaria
4 ] Constipation
3. In urticaria, histamine is the primary mediator; therefore, the antihistamines are the drugs of
choice and quite effective.
Pernicious anemia can develop in long-term treatment with which class of drugs?
Question Options
1 ] Histamine2 receptor antagonists (H2RAs)
2 ] Proton pump inhibitors (PPIs)
3 ] Antacids
4 ] Prokinetic agents
2. Total suppression of gastric acid long-term can lead to a lack of intrinsic factor, which is also
secreted by the parietal cells. Intrinsic factor is needed to facilitate absorption of vitamin B12.
A 54-year-old male patient is on Zyrtec daily for his chronic allergic rhinitis. He calls the
APN’s office to report that he missed a daily dose of this medication. Which statement is
accurate regarding missed doses of this medication?
1 ] Long-acting second-generation antihistamines should not be taken closer together than
prescribed, so missed doses must be held until the next dose (every 12 or 24 hours).
2 ] Long-acting first-generation antihistamines should not be taken closer together than
prescribed, so missed doses must be held until the next dose (every 12 or 24 hours).
Answer
A patient in the emergency room (ER) has been prescribed ondansetron for nausea. The
APN understands that this medication works by which mechanism?
1 ] Blocking dopamine receptors in the chemoreceptor trigger zone
2 ] Blocking histamine1 receptors in the gastrointestinal (GI) tract
3 ] Blocking serotonin on vagal nerve terminals
4 ] Stimulating gastric emptying and peristalsis
3. Blocking serotonin on vagal nerve terminals
Which classification of respiratory medications results in bronchodilation effects and
sputum volume reduction in patients with chronic obstructive pulmonary disease (COPD)?
1 ] Beta2 agonists
2 ] Methylxanthines
3 ] Muscarinic agents
4 ] Phosphodiesterase-4 (PDE-4) inhibitors
3. Muscarinic agents reduce the volume of sputum without changing the viscosity, in addition to
their bronchodilation effects.
Which condition is a clinical indication for antihistamines?
1 ] Nervousness
, 2 ] Headache
3 ] Urticaria
4 ] Constipation
3. In urticaria, histamine is the primary mediator; therefore, the antihistamines are the drugs of
choice and quite effective.
Pernicious anemia can develop in long-term treatment with which class of drugs?
Question Options
1 ] Histamine2 receptor antagonists (H2RAs)
2 ] Proton pump inhibitors (PPIs)
3 ] Antacids
4 ] Prokinetic agents
2. Total suppression of gastric acid long-term can lead to a lack of intrinsic factor, which is also
secreted by the parietal cells. Intrinsic factor is needed to facilitate absorption of vitamin B12.
A 54-year-old male patient is on Zyrtec daily for his chronic allergic rhinitis. He calls the
APN’s office to report that he missed a daily dose of this medication. Which statement is
accurate regarding missed doses of this medication?
1 ] Long-acting second-generation antihistamines should not be taken closer together than
prescribed, so missed doses must be held until the next dose (every 12 or 24 hours).
2 ] Long-acting first-generation antihistamines should not be taken closer together than
prescribed, so missed doses must be held until the next dose (every 12 or 24 hours).
