MSN 671 Quiz 1 Study Set.Final Test Paper 2026\2027.
What effect does a drug that acts as an
agonist for norepinephrine have on the
amount of norepinephrine in the synapse?
It would be expected to decrease the amount of
norepinephrine in the synapse.
What are drugs that interfere with reuptake
called?
Agonists.
What metabolizes drugs in the liver?
Cytochrome P-450 enzymes.
What is it called when a heavy drinker
requires more anesthesia than a comparable
person?
Cross tolerance.
,MSN 671 Quiz 1 Study Set.Final Test Paper 2026\2027.
What characteristic must a drug have to pass
rapidly through the capillaries surrounding
the brain?
It must be highly lipid soluble.
Which neurotransmitter is NOT taken back
into the presynaptic terminal via an active
reuptake mechanism?
Acetylcholine.
What does the therapeutic index refer to?
The relative safety of the drug.
What type of kinetics does a drug have if its
rate of metabolism is independent of its
plasma concentration?
Zero order kinetics.
What would we expect from a drug with a
high oil/water partition coefficient?
,MSN 671 Quiz 1 Study Set.Final Test Paper 2026\2027.
It would accumulate in the brain rapidly.
What does metabolism of a drug refer to?
Detoxification.
What is the main route of excretion for
drugs?
Renal system.
In the simplest form, what does
'pharmacokinetics' describe?
A drug's time course.
Where do psychoactive drugs commonly
depot bind?
All of the above (albumin in the blood, fatty
tissues, muscles).
When is a weak acid most ionized and least
able to pass through biological membranes?
In a medium with a pH of 9 (basic).
, MSN 671 Quiz 1 Study Set.Final Test Paper 2026\2027.
How permeable are the membranes that
separate fetal blood from maternal blood to
psychoactive drugs?
They are highly permeable to psychoactive
drugs.
What is the process called when the liver
metabolizes a drug by Glucoronic acid to the
drug molecule?
Conjugation.
What factors affect the pharmacokinetics of
a drug?
All of the above (genetics, physiological state,
species).
What happens as the oil/water partition
coefficient increases?
The drug becomes more lipid soluble.
What effect does a drug that acts as an
agonist for norepinephrine have on the
amount of norepinephrine in the synapse?
It would be expected to decrease the amount of
norepinephrine in the synapse.
What are drugs that interfere with reuptake
called?
Agonists.
What metabolizes drugs in the liver?
Cytochrome P-450 enzymes.
What is it called when a heavy drinker
requires more anesthesia than a comparable
person?
Cross tolerance.
,MSN 671 Quiz 1 Study Set.Final Test Paper 2026\2027.
What characteristic must a drug have to pass
rapidly through the capillaries surrounding
the brain?
It must be highly lipid soluble.
Which neurotransmitter is NOT taken back
into the presynaptic terminal via an active
reuptake mechanism?
Acetylcholine.
What does the therapeutic index refer to?
The relative safety of the drug.
What type of kinetics does a drug have if its
rate of metabolism is independent of its
plasma concentration?
Zero order kinetics.
What would we expect from a drug with a
high oil/water partition coefficient?
,MSN 671 Quiz 1 Study Set.Final Test Paper 2026\2027.
It would accumulate in the brain rapidly.
What does metabolism of a drug refer to?
Detoxification.
What is the main route of excretion for
drugs?
Renal system.
In the simplest form, what does
'pharmacokinetics' describe?
A drug's time course.
Where do psychoactive drugs commonly
depot bind?
All of the above (albumin in the blood, fatty
tissues, muscles).
When is a weak acid most ionized and least
able to pass through biological membranes?
In a medium with a pH of 9 (basic).
, MSN 671 Quiz 1 Study Set.Final Test Paper 2026\2027.
How permeable are the membranes that
separate fetal blood from maternal blood to
psychoactive drugs?
They are highly permeable to psychoactive
drugs.
What is the process called when the liver
metabolizes a drug by Glucoronic acid to the
drug molecule?
Conjugation.
What factors affect the pharmacokinetics of
a drug?
All of the above (genetics, physiological state,
species).
What happens as the oil/water partition
coefficient increases?
The drug becomes more lipid soluble.
