advanced pathophysiology NR 507 final
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Fat Soluble Hormones - ✔✔ANSWER ✔✔-Steroids
Water Soluble Hormones - ✔✔ANSWER ✔✔-Need 2nd
Messenger to transport across phospholipid membranes
,Pituitary Hormones - ✔✔ANSWER ✔✔-TSH, GH, ACTH,
FSH, LH, Oxytocin, ADH, Melanocyte Stimulating
Hormone
Anterior Pituitary - ✔✔ANSWER ✔✔-Acct for 75% of
total weight of pituitary gland. Three regions, pars
distalis, parts tuberalis, and pars intermedia. Pars distalis
is major component of Anterior Pituitary and source of
Anterior Pituitary Hormones.
Posterior Pituitary (neurohypophysis) - ✔✔ANSWER ✔✔-
Arises from 3rd ventricle of brain, consists of three parts,
median eminence, pituitary stalk, and infundibular
process (pars nervosa or neural tube). Median eminence
is composed mainly of nerve endings of axons that arise
primarily from ventral hypothalamus.
Hypothalamic releasing Hormones in Posterior pituitary's
median eminence. - ✔✔ANSWER ✔✔-Includes 10
hypothalamic releasing hormones and neurotransmitters
such as dopamine, norepinephrine, serotonin,
acetylcholine, and histamine.
,Pituitary stalk - ✔✔ANSWER ✔✔-contains axons of
neurons that originate in the supraoptic and
paraventricular nuclei of the hypothalamus.
Hormones of posterior pituitary - ✔✔ANSWER ✔✔-ADH,
and Oxytocin (Peptide Hormones)
ADH (antidiuretic Hormone) - ✔✔ANSWER ✔✔-Major
homeostatic function of posterior pituitary is control of
plasma osmolality, as regulated by ADH
Hypothalamic hormones and target tissues
(Hypophysiotropic hormones) - ✔✔ANSWER ✔✔-
HORMONES: Thyrotropin Releasing Hormone (TRH),
Gonadotropoin-releasing hormone (GnRH),
Somatostatin, Growth hormone-releasing hormone
(GHRH), corticotropin-releasing hormone (CRH),
Substance P, Dopamine, Prolactin-releasing factor.
TARGET Tissue: Anterior Pituitary
, Somatostatin - ✔✔ANSWER ✔✔-Inhibits release of
growth hormone and TSH
Gonadotropoin-releasing hormone - ✔✔ANSWER ✔✔-
Stimulates release of FSH and LH
Dopamine - ✔✔ANSWER ✔✔-Inhibits synthesis and
secretion of prolactin
Prolactin-releasing factor (PRF) - ✔✔ANSWER ✔✔-
Stimulate secretion of prolactin
Tropic Hormones of Anterior Pituitary and their function
- ✔✔ANSWER ✔✔-ACTH, Melanocyte-stimulating
Hormone (MSH, Somatotropic hormones, GH, prolactin,
LH, TSH, FSH, glycoprotein hormones
Adrenocorticotropic hormone (ACTH) - ✔✔ANSWER ✔✔-
SECRETORY CELL TYPE: Corticotropic
TARGET ORGANS: Adrenal Gland (cortex)