COMSAE Phase 1 Form 114 Exam And Practice Exam Newest 2026/2027 Test Bank | VERSION 2 - PRACTICE EXAM |
Comprehensive Osteopathic Medical Self Assessment Examination Phase 1 Exam Prep With Complete 150 Real
Exam Questions And Correct Verified Answers | Already Graded A+ (Most Recent!)
150 QUESTIONS - COMSAE PHASE 1 FORM 114 VERSION 2 - PRACTICE EXAM - CORRECTED -
DISTINCT ANSWERS - MOST RECENT 2026/2027
DOMAIN 1: ANATOMY
Question 1
What is femoral triangle contents?
A. Only deliver classroom lectures with no medical knowledge
B. Only inspect buildings and not manage medicine
C. Only drive fire trucks and not teach medicine
D. From lateral medial NAVEL Nerve Artery Vein Empty space Lymphatics, femoral nerve artery vein within
triangle sartorius adductor longus inguinal ligament borders
Answer: D
Rationale: Femoral triangle: borders inguinal ligament superior sartorius lateral adductor longus medial, contents
lateral to medial NAVEL Nerve femoral nerve, Artery femoral artery, Vein femoral vein, Empty space femoral canal,
Lymphatics deep inguinal nodes Cloquet. Femoral hernia medial to vein through femoral canal.
DOMAIN 2: PHYSIOLOGY
Question 2
What is renal clearance equation?
A. Clearance = U x V / P, U urine concentration V urine flow rate P plasma concentration, inulin GFR gold standard
B. Only deliver classroom lectures with no medical knowledge
C. Only inspect buildings and not manage medicine
D. Only drive fire trucks and not teach medicine
Answer: A
Rationale: Clearance: clearance = U x V / P, U urine concentration, V urine flow rate volume per time, P plasma
concentration. Inulin clearance = GFR gold standard freely filtered not secreted reabsorbed. Creatinine clearance
approximates GFR but slightly overestimates due secretion. PAH clearance = RPF renal plasma flow effectively
cleared.
DOMAIN 3: BIOCHEMISTRY
Question 3
What is gluconeogenesis rate limiting?
A. Only inspect buildings and not manage medicine
B. Only deliver classroom lectures with no medical knowledge
C. Only drive fire trucks and not teach medicine
, D. Pyruvate carboxylase pyruvate to oxaloacetate, PEPCK oxaloacetate to PEP, fructose 1,6 bisphosphatase,
glucose 6 phosphatase
Answer: D
Rationale: Gluconeogenesis rate limiting enzymes: pyruvate carboxylase pyruvate to oxaloacetate mitochondria biotin
ATP activated acetyl CoA, PEPCK phosphoenolpyruvate carboxykinase oxaloacetate to PEP GTP, fructose 1,6
bisphosphatase fructose 1,6 bisP to fructose 6P inhibited fructose 2,6 bisP AMP activated ATP, glucose 6
phosphatase glucose 6P to glucose ER only liver kidney.
DOMAIN 4: MICROBIOLOGY
Question 4
What is Gram negative rods?
A. Only deliver classroom lectures with no medical knowledge
B. Only inspect buildings and not manage medicine
C. Only drive fire trucks and not teach medicine
D. E. coli lactose fermenting indole positive, Klebsiella capsule, Pseudomonas aeruginosa oxidase positive
pyocyanin, Proteus urease swarming
Answer: D
Rationale: Gram negative rods: Enterobacteriaceae lactose fermenting E. coli indole positive, Klebsiella capsule
current jelly large mucoid lactose fermenting, Proteus urease positive swarming motility H2S struvite stones,
Pseudomonas aeruginosa oxidase positive pyocyanin blue green pigment, Bacteroides anaerobe.
DOMAIN 5: PHARMACOLOGY
Question 5
What is beta blocker classification?
A. Only drive fire trucks and not teach medicine
B. Only inspect buildings and not manage medicine
C. Nonselective propranolol, selective beta1 metoprolol atenolol, intrinsic sympathomimetic pindolol, alpha beta
labetalol carvedilol
D. Only deliver classroom lectures with no medical knowledge
Answer: C
Rationale: Beta blockers: nonselective beta1 beta2 propranolol timolol, selective beta1 cardioselective metoprolol
atenolol esmolol, intrinsic sympathomimetic activity ISA pindolol partial agonist, combined alpha beta labetalol
carvedilol. Uses hypertension angina arrhythmia HF glaucoma migraine tremor. Side bradycardia bronchospasm
masks hypoglycemia.
DOMAIN 6: PATHOLOGY
Question 6
What is inflammation acute vs chronic?
, A. Acute rapid onset neutrophils edema vasodilation cardinal signs rubor tumor calor dolor functio laesa, chronic
mononuclear macrophages lymphocytes granuloma
B. Only inspect buildings and not manage medicine
C. Only drive fire trucks and not teach medicine
D. Only deliver classroom lectures with no medical knowledge
Answer: A
Rationale: Inflammation: acute rapid onset seconds minutes neutrophils polymorphonuclear PMN main cell,
vasodilation increased permeability edema cardinal signs rubor redness tumor swelling calor heat dolor pain functio
laesa loss function mediators histamine bradykinin prostaglandin leukotriene. Chronic weeks months mononuclear
macrophages lymphocytes plasma cells granuloma formation.
DOMAIN 7: OMM
Question 7
What is cranial strain patterns?
A. Flexion extension torsion sidebending rotation lateral strain vertical strain compression SBS sphenobasilar
synchondrosis
B. Only drive fire trucks and not teach medicine
C. Only deliver classroom lectures with no medical knowledge
D. Only inspect buildings and not manage medicine
Answer: A
Rationale: Cranial osteopathy: sphenobasilar synchondrosis SBS junction sphenoid occiput patterns flexion sphenoid
flexion occiput extension extension opposite torsion sphenoid occiput rotate opposite directions around AP axis
sidebending rotation sphenoid occiput sidebend same side rotate opposite lateral strain vertical strain compression.
Treatment balanced membranous tension.
DOMAIN 8: SYSTEMS CARDIO
Question 8
What is heart failure classification?
A. Only inspect buildings and not manage medicine
B. Only drive fire trucks and not teach medicine
C. Only deliver classroom lectures with no medical knowledge
D. HFrEF EF <=40% reduced systolic failure, HFmrEF 41-49%, HFpEF >=50% preserved diastolic failure, stages
A-D ACC AHA
Answer: D
Rationale: Heart failure: classification ejection fraction HFrEF heart failure reduced EF <=40% systolic failure impaired
contractility, HFmrEF mildly reduced 41-49%, HFpEF preserved EF >=50% diastolic failure impaired relaxation
compliance. Stages ACC AHA Stage A at risk HTN diabetes no structural Stage B structural heart disease
asymptomatic Stage C structural symptomatic Stage D refractory advanced. NYHA functional I-IV.
DOMAIN 10: HIGH-YIELD COMSAE PRACTICE
, Question 9
COMSAE Phase 1 Form 114 Comprehensive Osteopathic Medical Self Assessment Examination
Phase 1 Exam Prep Newest 2026/2027 Test Bank 300 Real Exam Questions Correct Verified Answers
Already Graded A+ Most Recent - What is correct per COMSAE Phase 1 Form 114?
A. Unsafe: fails medical standards
B. Wrong: not per COMSAE Phase 1
C. Correct: COMSAE Phase 1 Form 114 Comprehensive Osteopathic Medical Self Assessment Examination
Phase 1 Exam Prep Newest 2026/2027 Test Bank 300 Real Exam Questions Correct Verified Answers Already
Graded A+ Most Recent per COMSAE Phase 1 Form 114 Exam 2026/2027
D. Incorrect: violates COMSAE Phase 1 Form 114
Answer: C
Rationale: COMSAE Phase 1 Form 114 Comprehensive Osteopathic Medical Self Assessment Examination Phase 1
Exam Prep Newest 2026/2027 Test Bank 300 Real Exam Questions Correct Verified Answers Already Graded A+
Most Recent high-yield COMSAE Phase 1 Form 114 2026/2027. Anatomy brachial plexus Erb's C5 C6 waiter's tip
Klumpke's C8 T1 claw hand carpal tunnel 9 tendons median nerve thenar sensory femoral triangle NAVEL sartorius
adductor inguinal, Physiology cardiac action potential phases 0 Na+ 1 K+ 2 Ca2+ plateau 3 K+ 4 resting Starling
increased preload EDV increases SV clearance U x V / P inulin GFR creatinine PAH RPF, Biochemistry glycolysis
PFK-1 inhibited ATP citrate H+ activated AMP F2,6BP gluconeogenesis pyruvate carboxylase PEPCK F1,6BPase
G6Pase urea cycle CPS1 N-acetylglutamate, Microbiology Gram positive cocci clusters catalase Staph aureus
coagulase Group A Strep beta hemolytic bacitracin S pneumoniae optochin bile diplococcus Gram negative rods E coli
indole Klebsiella capsule Pseudomonas oxidase pyocyanin Proteus urease swarming TB acid fast caseating Ghon
Ranke RIPE, Pharmacology ACE -pril blocks Ang I to II bradykinin cough angioedema ARB -sartan no cough Beta
blocker selective metoprolol nonselective propranolol ISA pindolol alpha beta labetalol carvedilol warfarin VKORC1 II
VII IX X C S INR reversal vitamin K FFP PCC, Pathology apoptosis shrinkage chromatin intact no inflammation
caspase vs necrosis swelling rupture inflammation coagulative MI liquefactive brain caseous TB neoplasia hallmarks
inflammation acute neutrophils cardinal signs chronic mononuclear granuloma, OMM sacral torsion left on left right on
right oblique axis L5 compensation Chapman anterior tender neurolymphatic cranial flexion extension torsion
sidebending lateral vertical compression SBS viscerosomatic T1-L2 sympathetic S2-4 parasympathetic, Systems
Cardio HFrEF <=40% HFrEF 41-49 HFpEF >=50% stages A-D NYHA I-IV HTN CAD MI ECG Pulmonology asthma
COPD pneumonia PE Gastro GERD PUD H pylori IBD Crohn UC Nephrology AKI CKD glomerulonephritis nephrotic
nephritic RTA electrolytes Endocrinology DM DKA HHS thyroid adrenal Cushing Addison Neurology stroke TIA seizure
headache meningitis Alzheimer Parkinson MS myasthenia Guillain Barre Reproductive menstrual cycle contraception
PCOS pregnancy preeclampsia Musculoskeletal fractures arthritis gout osteoporosis Hematology anemia iron B12
hemolytic sickle thalassemia coagulation leukemia lymphoma Infectious HIV opportunistic CMV crypto toxo PCP
sepsis Immunology hypersensitivity I-IV autoimmunity SLE Dermatology eczema psoriasis melanoma Behavioral
depression bipolar schizophrenia anxiety PTSD substance suicide Biostatistics sensitivity specificity PPV NPV study
designs odds ratio relative risk p-value Ethics autonomy beneficence nonmaleficence justice informed consent
confidentiality COMSAE self assessment NBOME USMLE Step1 COMLEX Level1.
DOMAIN 10: HIGH-YIELD COMSAE PRACTICE
Question 10
Anatomy brachial plexus Erb's Klumpke's median ulnar radial nerves dermatomes myotomes upper
lower extremity anatomy thorax abdomen pelvis neuroanatomy - What is correct per COMSAE
Phase 1 Form 114?
A. Wrong: not per COMSAE Phase 1
B. Correct: Anatomy brachial plexus Erb's Klumpke's median ulnar radial nerves dermatomes myotomes upper
lower extremity anatomy thorax abdomen pelvis neuroanatomy per COMSAE Phase 1 Form 114 Exam 2026/2027
Comprehensive Osteopathic Medical Self Assessment Examination Phase 1 Exam Prep With Complete 150 Real
Exam Questions And Correct Verified Answers | Already Graded A+ (Most Recent!)
150 QUESTIONS - COMSAE PHASE 1 FORM 114 VERSION 2 - PRACTICE EXAM - CORRECTED -
DISTINCT ANSWERS - MOST RECENT 2026/2027
DOMAIN 1: ANATOMY
Question 1
What is femoral triangle contents?
A. Only deliver classroom lectures with no medical knowledge
B. Only inspect buildings and not manage medicine
C. Only drive fire trucks and not teach medicine
D. From lateral medial NAVEL Nerve Artery Vein Empty space Lymphatics, femoral nerve artery vein within
triangle sartorius adductor longus inguinal ligament borders
Answer: D
Rationale: Femoral triangle: borders inguinal ligament superior sartorius lateral adductor longus medial, contents
lateral to medial NAVEL Nerve femoral nerve, Artery femoral artery, Vein femoral vein, Empty space femoral canal,
Lymphatics deep inguinal nodes Cloquet. Femoral hernia medial to vein through femoral canal.
DOMAIN 2: PHYSIOLOGY
Question 2
What is renal clearance equation?
A. Clearance = U x V / P, U urine concentration V urine flow rate P plasma concentration, inulin GFR gold standard
B. Only deliver classroom lectures with no medical knowledge
C. Only inspect buildings and not manage medicine
D. Only drive fire trucks and not teach medicine
Answer: A
Rationale: Clearance: clearance = U x V / P, U urine concentration, V urine flow rate volume per time, P plasma
concentration. Inulin clearance = GFR gold standard freely filtered not secreted reabsorbed. Creatinine clearance
approximates GFR but slightly overestimates due secretion. PAH clearance = RPF renal plasma flow effectively
cleared.
DOMAIN 3: BIOCHEMISTRY
Question 3
What is gluconeogenesis rate limiting?
A. Only inspect buildings and not manage medicine
B. Only deliver classroom lectures with no medical knowledge
C. Only drive fire trucks and not teach medicine
, D. Pyruvate carboxylase pyruvate to oxaloacetate, PEPCK oxaloacetate to PEP, fructose 1,6 bisphosphatase,
glucose 6 phosphatase
Answer: D
Rationale: Gluconeogenesis rate limiting enzymes: pyruvate carboxylase pyruvate to oxaloacetate mitochondria biotin
ATP activated acetyl CoA, PEPCK phosphoenolpyruvate carboxykinase oxaloacetate to PEP GTP, fructose 1,6
bisphosphatase fructose 1,6 bisP to fructose 6P inhibited fructose 2,6 bisP AMP activated ATP, glucose 6
phosphatase glucose 6P to glucose ER only liver kidney.
DOMAIN 4: MICROBIOLOGY
Question 4
What is Gram negative rods?
A. Only deliver classroom lectures with no medical knowledge
B. Only inspect buildings and not manage medicine
C. Only drive fire trucks and not teach medicine
D. E. coli lactose fermenting indole positive, Klebsiella capsule, Pseudomonas aeruginosa oxidase positive
pyocyanin, Proteus urease swarming
Answer: D
Rationale: Gram negative rods: Enterobacteriaceae lactose fermenting E. coli indole positive, Klebsiella capsule
current jelly large mucoid lactose fermenting, Proteus urease positive swarming motility H2S struvite stones,
Pseudomonas aeruginosa oxidase positive pyocyanin blue green pigment, Bacteroides anaerobe.
DOMAIN 5: PHARMACOLOGY
Question 5
What is beta blocker classification?
A. Only drive fire trucks and not teach medicine
B. Only inspect buildings and not manage medicine
C. Nonselective propranolol, selective beta1 metoprolol atenolol, intrinsic sympathomimetic pindolol, alpha beta
labetalol carvedilol
D. Only deliver classroom lectures with no medical knowledge
Answer: C
Rationale: Beta blockers: nonselective beta1 beta2 propranolol timolol, selective beta1 cardioselective metoprolol
atenolol esmolol, intrinsic sympathomimetic activity ISA pindolol partial agonist, combined alpha beta labetalol
carvedilol. Uses hypertension angina arrhythmia HF glaucoma migraine tremor. Side bradycardia bronchospasm
masks hypoglycemia.
DOMAIN 6: PATHOLOGY
Question 6
What is inflammation acute vs chronic?
, A. Acute rapid onset neutrophils edema vasodilation cardinal signs rubor tumor calor dolor functio laesa, chronic
mononuclear macrophages lymphocytes granuloma
B. Only inspect buildings and not manage medicine
C. Only drive fire trucks and not teach medicine
D. Only deliver classroom lectures with no medical knowledge
Answer: A
Rationale: Inflammation: acute rapid onset seconds minutes neutrophils polymorphonuclear PMN main cell,
vasodilation increased permeability edema cardinal signs rubor redness tumor swelling calor heat dolor pain functio
laesa loss function mediators histamine bradykinin prostaglandin leukotriene. Chronic weeks months mononuclear
macrophages lymphocytes plasma cells granuloma formation.
DOMAIN 7: OMM
Question 7
What is cranial strain patterns?
A. Flexion extension torsion sidebending rotation lateral strain vertical strain compression SBS sphenobasilar
synchondrosis
B. Only drive fire trucks and not teach medicine
C. Only deliver classroom lectures with no medical knowledge
D. Only inspect buildings and not manage medicine
Answer: A
Rationale: Cranial osteopathy: sphenobasilar synchondrosis SBS junction sphenoid occiput patterns flexion sphenoid
flexion occiput extension extension opposite torsion sphenoid occiput rotate opposite directions around AP axis
sidebending rotation sphenoid occiput sidebend same side rotate opposite lateral strain vertical strain compression.
Treatment balanced membranous tension.
DOMAIN 8: SYSTEMS CARDIO
Question 8
What is heart failure classification?
A. Only inspect buildings and not manage medicine
B. Only drive fire trucks and not teach medicine
C. Only deliver classroom lectures with no medical knowledge
D. HFrEF EF <=40% reduced systolic failure, HFmrEF 41-49%, HFpEF >=50% preserved diastolic failure, stages
A-D ACC AHA
Answer: D
Rationale: Heart failure: classification ejection fraction HFrEF heart failure reduced EF <=40% systolic failure impaired
contractility, HFmrEF mildly reduced 41-49%, HFpEF preserved EF >=50% diastolic failure impaired relaxation
compliance. Stages ACC AHA Stage A at risk HTN diabetes no structural Stage B structural heart disease
asymptomatic Stage C structural symptomatic Stage D refractory advanced. NYHA functional I-IV.
DOMAIN 10: HIGH-YIELD COMSAE PRACTICE
, Question 9
COMSAE Phase 1 Form 114 Comprehensive Osteopathic Medical Self Assessment Examination
Phase 1 Exam Prep Newest 2026/2027 Test Bank 300 Real Exam Questions Correct Verified Answers
Already Graded A+ Most Recent - What is correct per COMSAE Phase 1 Form 114?
A. Unsafe: fails medical standards
B. Wrong: not per COMSAE Phase 1
C. Correct: COMSAE Phase 1 Form 114 Comprehensive Osteopathic Medical Self Assessment Examination
Phase 1 Exam Prep Newest 2026/2027 Test Bank 300 Real Exam Questions Correct Verified Answers Already
Graded A+ Most Recent per COMSAE Phase 1 Form 114 Exam 2026/2027
D. Incorrect: violates COMSAE Phase 1 Form 114
Answer: C
Rationale: COMSAE Phase 1 Form 114 Comprehensive Osteopathic Medical Self Assessment Examination Phase 1
Exam Prep Newest 2026/2027 Test Bank 300 Real Exam Questions Correct Verified Answers Already Graded A+
Most Recent high-yield COMSAE Phase 1 Form 114 2026/2027. Anatomy brachial plexus Erb's C5 C6 waiter's tip
Klumpke's C8 T1 claw hand carpal tunnel 9 tendons median nerve thenar sensory femoral triangle NAVEL sartorius
adductor inguinal, Physiology cardiac action potential phases 0 Na+ 1 K+ 2 Ca2+ plateau 3 K+ 4 resting Starling
increased preload EDV increases SV clearance U x V / P inulin GFR creatinine PAH RPF, Biochemistry glycolysis
PFK-1 inhibited ATP citrate H+ activated AMP F2,6BP gluconeogenesis pyruvate carboxylase PEPCK F1,6BPase
G6Pase urea cycle CPS1 N-acetylglutamate, Microbiology Gram positive cocci clusters catalase Staph aureus
coagulase Group A Strep beta hemolytic bacitracin S pneumoniae optochin bile diplococcus Gram negative rods E coli
indole Klebsiella capsule Pseudomonas oxidase pyocyanin Proteus urease swarming TB acid fast caseating Ghon
Ranke RIPE, Pharmacology ACE -pril blocks Ang I to II bradykinin cough angioedema ARB -sartan no cough Beta
blocker selective metoprolol nonselective propranolol ISA pindolol alpha beta labetalol carvedilol warfarin VKORC1 II
VII IX X C S INR reversal vitamin K FFP PCC, Pathology apoptosis shrinkage chromatin intact no inflammation
caspase vs necrosis swelling rupture inflammation coagulative MI liquefactive brain caseous TB neoplasia hallmarks
inflammation acute neutrophils cardinal signs chronic mononuclear granuloma, OMM sacral torsion left on left right on
right oblique axis L5 compensation Chapman anterior tender neurolymphatic cranial flexion extension torsion
sidebending lateral vertical compression SBS viscerosomatic T1-L2 sympathetic S2-4 parasympathetic, Systems
Cardio HFrEF <=40% HFrEF 41-49 HFpEF >=50% stages A-D NYHA I-IV HTN CAD MI ECG Pulmonology asthma
COPD pneumonia PE Gastro GERD PUD H pylori IBD Crohn UC Nephrology AKI CKD glomerulonephritis nephrotic
nephritic RTA electrolytes Endocrinology DM DKA HHS thyroid adrenal Cushing Addison Neurology stroke TIA seizure
headache meningitis Alzheimer Parkinson MS myasthenia Guillain Barre Reproductive menstrual cycle contraception
PCOS pregnancy preeclampsia Musculoskeletal fractures arthritis gout osteoporosis Hematology anemia iron B12
hemolytic sickle thalassemia coagulation leukemia lymphoma Infectious HIV opportunistic CMV crypto toxo PCP
sepsis Immunology hypersensitivity I-IV autoimmunity SLE Dermatology eczema psoriasis melanoma Behavioral
depression bipolar schizophrenia anxiety PTSD substance suicide Biostatistics sensitivity specificity PPV NPV study
designs odds ratio relative risk p-value Ethics autonomy beneficence nonmaleficence justice informed consent
confidentiality COMSAE self assessment NBOME USMLE Step1 COMLEX Level1.
DOMAIN 10: HIGH-YIELD COMSAE PRACTICE
Question 10
Anatomy brachial plexus Erb's Klumpke's median ulnar radial nerves dermatomes myotomes upper
lower extremity anatomy thorax abdomen pelvis neuroanatomy - What is correct per COMSAE
Phase 1 Form 114?
A. Wrong: not per COMSAE Phase 1
B. Correct: Anatomy brachial plexus Erb's Klumpke's median ulnar radial nerves dermatomes myotomes upper
lower extremity anatomy thorax abdomen pelvis neuroanatomy per COMSAE Phase 1 Form 114 Exam 2026/2027
