Huether and McCance: Understanding Pathophysiology, 5th
Edition
Chapter 01: Cellular Biology
Test Bank
MULTIPLE CHOICE
A student is observing a cell under the microscope. It is
observed to have supercoiled DNA with histones. Which of the
following would also be observed by the student?
A single circular chromosome
A nucleus
Free-floating nuclear material
No organelles
ANS: B
The cell described is a eukaryotic cell, so it has histones and a
supercoiled DNA within its nucleus; thus, the nucleus should be
observed.
A single circular chromosome is characteristic of prokaryotic cells,
which do not have histones.
Free-floating nuclear material describes a prokaryotic cell, which
would not have a distinct nucleus.
Eukaryotic cells have membrane bounded cellular components called
organelles. No
organelles describes a prokaryotic cell.
REF: p. 2
A nurse is instructing the staff about cellular functions. Which
cellular function is the nurse describing when an isolated cell
absorbs oxygen and uses it to transform nutrients to energy?
Metabolic absorption
Communication
, Secretion
Respiration
ANS: D
The ability of the cell to absorb oxygen refers to the cell’s function of
respiration.
The ability of the cell to function within a society of cells refers to
its function of communication.
The ability of the cell to take in nutrients refers to the cell’s function
of metabolic absorption.
The ability of the cell to synthesize new substances and secrete these
elsewhere refers
to the cell’s function of secretion.
REF: p. 3
A eukaryotic cell is undergoing DNA replication. In which region
of the cell would most of the genetic information be contained?
Mitochondria
Ribosome
Nucleolus
Nucleus
ANS: C
The region of the cell that contains genetic material, including a
large amount of ribonucleic acid, most of the DNA, and DNA-
binding proteins, is the nucleolus. The mitochondria is the site of
cellular respiration.
The ribosomes are involved in manufacturing of proteins within the cell.
The nucleus contains the nucleolus, and it is the nucleolus that contains
genetic
material.
,REF: p. 5
The fluid mosaic model for biologic membranes describes
membrane behavior. According to this model, which of the
following float singly or as aggregates in the fluid lipid bilayer?
Peripheral membrane proteins
Integral membrane proteins
Glycoproteins
Cell adhesion molecules
ANS: B
Integral membrane proteins float freely in the fluid lipid bilayer.
Peripheral membrane proteins are not embedded in the layer, but reside
at the surface.
Glycoproteins act as cell surface markers.
Cell adhesion molecules are on the outside of the membrane and allow
cells to hook
together.
REF: p. 6
5. Which of the following can bind to plasma membrane receptors?
Oxygen
Ribosomes
Amphipathic lipids
Ligands
ANS: D
Ligands are specific molecules that can bind with receptors on the
cell membrane.
Oxygen moves by diffusion; it does not bind to receptors.
Ribosomes make proteins and are not involved in binding.
Amphipathic lipids are a portion of the cell membrane.
REF: p. 11
, A nurse is reviewing a report from a patient with metastatic
cancer. What finding would support the diagnosis of metastatic
cancer? Alterations in extracellular matrix that include:
Decreased fibronectin
Increased collagen
Decreased elastin
Increased glycoproteins
ANS: A
Reduced amounts of fibronectin are found in some types of
cancerous cells, allowing cancer cells to travel, or metastasize.
Collagen provides strength, and its breakdown is associated with
osteoarthritis, not cancer.
Elastin is found in the lungs and allows tissues to stretch; it is
not associated with cancerous cells.
Decreased, not increased, glycoproteins are associated with
cancerous cells. REF: p. 8
Which form of cell communication is used to relate to other cells
in direct physical contact?
Cell junction
Gap junction
Desmosomes
Tight junctions
ANS: A
Cell junctions hold cells together and permit molecules to pass
from cell to cell. Gap junctions allow communication from the
inside of one cell to the inside of another.
Desmosomes are not involved in communication, but allow cells to hold
together.
Edition
Chapter 01: Cellular Biology
Test Bank
MULTIPLE CHOICE
A student is observing a cell under the microscope. It is
observed to have supercoiled DNA with histones. Which of the
following would also be observed by the student?
A single circular chromosome
A nucleus
Free-floating nuclear material
No organelles
ANS: B
The cell described is a eukaryotic cell, so it has histones and a
supercoiled DNA within its nucleus; thus, the nucleus should be
observed.
A single circular chromosome is characteristic of prokaryotic cells,
which do not have histones.
Free-floating nuclear material describes a prokaryotic cell, which
would not have a distinct nucleus.
Eukaryotic cells have membrane bounded cellular components called
organelles. No
organelles describes a prokaryotic cell.
REF: p. 2
A nurse is instructing the staff about cellular functions. Which
cellular function is the nurse describing when an isolated cell
absorbs oxygen and uses it to transform nutrients to energy?
Metabolic absorption
Communication
, Secretion
Respiration
ANS: D
The ability of the cell to absorb oxygen refers to the cell’s function of
respiration.
The ability of the cell to function within a society of cells refers to
its function of communication.
The ability of the cell to take in nutrients refers to the cell’s function
of metabolic absorption.
The ability of the cell to synthesize new substances and secrete these
elsewhere refers
to the cell’s function of secretion.
REF: p. 3
A eukaryotic cell is undergoing DNA replication. In which region
of the cell would most of the genetic information be contained?
Mitochondria
Ribosome
Nucleolus
Nucleus
ANS: C
The region of the cell that contains genetic material, including a
large amount of ribonucleic acid, most of the DNA, and DNA-
binding proteins, is the nucleolus. The mitochondria is the site of
cellular respiration.
The ribosomes are involved in manufacturing of proteins within the cell.
The nucleus contains the nucleolus, and it is the nucleolus that contains
genetic
material.
,REF: p. 5
The fluid mosaic model for biologic membranes describes
membrane behavior. According to this model, which of the
following float singly or as aggregates in the fluid lipid bilayer?
Peripheral membrane proteins
Integral membrane proteins
Glycoproteins
Cell adhesion molecules
ANS: B
Integral membrane proteins float freely in the fluid lipid bilayer.
Peripheral membrane proteins are not embedded in the layer, but reside
at the surface.
Glycoproteins act as cell surface markers.
Cell adhesion molecules are on the outside of the membrane and allow
cells to hook
together.
REF: p. 6
5. Which of the following can bind to plasma membrane receptors?
Oxygen
Ribosomes
Amphipathic lipids
Ligands
ANS: D
Ligands are specific molecules that can bind with receptors on the
cell membrane.
Oxygen moves by diffusion; it does not bind to receptors.
Ribosomes make proteins and are not involved in binding.
Amphipathic lipids are a portion of the cell membrane.
REF: p. 11
, A nurse is reviewing a report from a patient with metastatic
cancer. What finding would support the diagnosis of metastatic
cancer? Alterations in extracellular matrix that include:
Decreased fibronectin
Increased collagen
Decreased elastin
Increased glycoproteins
ANS: A
Reduced amounts of fibronectin are found in some types of
cancerous cells, allowing cancer cells to travel, or metastasize.
Collagen provides strength, and its breakdown is associated with
osteoarthritis, not cancer.
Elastin is found in the lungs and allows tissues to stretch; it is
not associated with cancerous cells.
Decreased, not increased, glycoproteins are associated with
cancerous cells. REF: p. 8
Which form of cell communication is used to relate to other cells
in direct physical contact?
Cell junction
Gap junction
Desmosomes
Tight junctions
ANS: A
Cell junctions hold cells together and permit molecules to pass
from cell to cell. Gap junctions allow communication from the
inside of one cell to the inside of another.
Desmosomes are not involved in communication, but allow cells to hold
together.
